Luteolin suppresses the JAK/STAT pathway in a cellular model of intestinal inflammation

Nitric oxide as a potential biomarker in inflammatory bowel disease

(2017) Nesina Avdagić et al.   Bosnian Journal of Basic Medical Sciences

Molecular targets of luteolin in cancer

(2016) Muobarak J. Tuorkey   EUROPEAN JOURNAL OF CANCER PREVENTION

Luteolin protects the hippocampus against neuron impairments induced by kainic acid in rats

(2016) Tzu Yu Lin et al.   NEUROTOXICOLOGY

Red wine polyphenol extract efficiently protects intestinal epithelial cells from inflammation via opposite modulation of JAK/STAT and Nrf2 pathways

(2016) Carla Nunes et al.   Toxicology Research

Randomized trial of tofacitinib in active ulcerative colitis: analysis of efficacy based on patient-reported outcomes

(2015) Julián Panés et al.   BMC GASTROENTEROLOGY

Anti-Inflammatory Activity of Butein and Luteolin Through Suppression of NFκB Activation and Induction of Heme Oxygenase-1

(2015) Jeehye Sung et al.   JOURNAL OF MEDICINAL FOOD

Luteolin protects against vascular inflammation in mice and TNF-alpha-induced monocyte adhesion to endothelial cells via suppressing IΚBα/NF-κB signaling pathway

(2015) Zhenquan Jia et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

STAT1 modification improves therapeutic effects of interferons on lung cancer cells

(2015) Junjie Chen et al.   Journal of Translational Medicine

Luteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancer

(2015) Jun Lu et al.   Journal of Translational Medicine

Immunopathogenesis of IBD: current state of the art

(2015) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

Role of Polyphenols and Other Phytochemicals on Molecular Signaling

(2015) Swapna Upadhyay et al.   Oxidative Medicine and Cellular Longevity

Inflammatory Bowel Disease

(2015) Talha A. Malik   SURGICAL CLINICS OF NORTH AMERICA

Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation

(2015) Maria Hytti et al.   Scientific Reports

Tofacitinib

(2014) Deepti Vyas et al.   ANNALS OF PHARMACOTHERAPY

Luteolin Arrests Cell Cycling, Induces Apoptosis and Inhibits the JAK/STAT3 Pathway in Human Cholangiocarcinoma Cells

(2014) Ploypailin Aneknan et al.   Asian Pacific Journal of Cancer Prevention

Over-expression of COX-2 mRNA in colorectal cancer

(2014) Hennie MJ Roelofs et al.   BMC GASTROENTEROLOGY

Forsythin inhibits lipopolysaccharide-induced inflammation by suppressing JAK-STAT and p38 MAPK signalings and ROS production

(2014) Xiaolong Pan et al.   INFLAMMATION RESEARCH

Luteolin, a bioflavonoid inhibits azoxymethane-induced colon carcinogenesis: Involvement of iNOS and COX-2

(2014) Sudhandiran Ganapasam et al.   Pharmacognosy Magazine

Treatment of inflammatory bowel disease (IBD)

(2014) Anand B. Pithadia et al.   Pharmacological Reports

Luteolin Inhibits Human Keratinocyte Activation and Decreases NF-κB Induction That Is Increased in Psoriatic Skin

(2014) Zuyi Weng et al.   PLoS One

Higher Activity of the Inducible Nitric Oxide Synthase Contributes to Very Early Onset Inflammatory Bowel Disease

(2014) Sandeep S Dhillon et al.   Clinical and Translational Gastroenterology

Intestinal anti-inflammatory activity of luteolin: Role of the aglycone in NF-κB inactivation in macrophages co-cultured with intestinal epithelial cells

(2013) Yosuke Nishitani et al.   BIOFACTORS

Stimulated human melanocytes express and release interleukin-8, which is inhibited by luteolin: relevance to early vitiligo

(2013) A. Miniati et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Drug advances in inflammatory bowel disease

(2013) R. A. Speight et al.   CLINICAL MEDICINE

Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation

(2013) WARAPORN MALILAS et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Luteolin and luteolin-7-O-glucoside inhibit lipopolysaccharide-induced inflammatory responses through modulation of NF-κB/AP-1/PI3K-Akt signaling cascades in RAW 264.7 cells

(2013) Chung Mu Park et al.   Nutrition Research and Practice

Involvement of JAK/STAT signaling in the pathogenesis of inflammatory bowel disease

(2013) Mehmet Coskun et al.   PHARMACOLOGICAL RESEARCH

Tofacitinib, an Oral Janus Kinase Inhibitor, in Active Ulcerative Colitis

(2012) William J. Sandborn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oxidative stress suppression by luteolin-induced heme oxygenase-1 expression

(2012) Gui-bo Sun et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Intestinal anti-inflammatory activity of red wine extract: unveiling the mechanisms in colonic epithelial cells

(2012) Carla Nunes et al.   Food & Function

JAK/STAT/SOCS-signaling pathway and colon and rectal cancer

(2011) Martha L. Slattery et al.   MOLECULAR CARCINOGENESIS

NF-κB Signaling Pathway, Inflammation and Colorectal Cancer

(2010) Soly Wang et al.   Cellular & Molecular Immunology

IL-8 as an important chemoattractant for neutrophils in ulcerative colitis and Crohn's disease

(2010) K. MITSUYAMA et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Luteolin inhibits cytokine expression in endotoxin/cytokine-stimulated microglia

(2010) Tsung-Kuei Kao et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Basic biochemical mechanisms behind the health benefits of polyphenols

(2010) Cesar G. Fraga et al.   MOLECULAR ASPECTS OF MEDICINE

Luteolin Isolated from the Flowers of Lonicera japonica Suppresses Inflammatory Mediator Release by Blocking NF-κB and MAPKs Activation Pathways in HMC-1 Cells

(2010) Ok-Hwa Kang et al.   MOLECULES

Recent Advances on the Roles of NO in Cancer and Chronic Inflammatory Disorders

(2009) Jagat Kanwar et al.   CURRENT MEDICINAL CHEMISTRY

Dietary polyphenols can modulate the intestinal inflammatory response

(2009) Béatrice Romier et al.   NUTRITION REVIEWS

The role of COX-2 in intestinal inflammation and colorectal cancer

(2009) D Wang et al.   ONCOGENE

NF-κB in inflammatory bowel disease

(2008) I. Atreya et al.   JOURNAL OF INTERNAL MEDICINE

Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

(2008) Kavon Rezai-Zadeh et al.   Journal of Neuroinflammation

Inteferons pen the JAK–STAT pathway

(2008) Christian Schindler et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

MAPK-induced Ser727phosphorylation promotes SUMOylation of STAT1

(2007) Sari Vanhatupa et al.   BIOCHEMICAL JOURNAL