Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation
Authors
Keywords
-
Journal
Scientific Reports
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-12-01
DOI
10.1038/srep17645
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Quercetin alleviates 4-hydroxynonenal-induced cytotoxicity and inflammation in ARPE-19 cells
- (2015) Maria Hytti et al. EXPERIMENTAL EYE RESEARCH
- Decline in cellular clearance systems induces inflammasome signaling in human ARPE-19 cells
- (2014) Niina Piippo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Fisetin Up-regulates the Expression of Adiponectin in 3T3-L1 Adipocytes via the Activation of Silent Mating Type Information Regulation 2 Homologue 1 (SIRT1)-Deacetylase and Peroxisome Proliferator-Activated Receptors (PPARs)
- (2014) Taewon Jin et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Luteolin Protects HUVECs from TNF-α-induced Oxidative Stress and Inflammation via its Effects on the Nox4/ROS-NF-κB and MAPK Pathways
- (2014) Fan Xia et al. Journal of Atherosclerosis and Thrombosis
- Resveratrol prevents the development of choroidal neovascularization by modulating AMP-activated protein kinase in macrophages and other cell types
- (2014) Norihiro Nagai et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Fisetin Inhibits Human Melanoma Cell Invasion through Promotion of Mesenchymal to Epithelial Transition and by Targeting MAPK and NFκB Signaling Pathways
- (2014) Harish Chandra Pal et al. PLoS One
- Small molecule SIRT1 activators for the treatment of aging and age-related diseases
- (2014) Basil P. Hubbard et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders
- (2013) Anu Kauppinen et al. CELLULAR SIGNALLING
- Cellular and molecular mechanisms of age-related macular degeneration: From impaired autophagy to neovascularization
- (2013) Alexa Klettner et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Sirtuin deacylases: a molecular link between metabolism and immunity
- (2013) Nicolas Preyat et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Luteolin Inhibits Inflammatory Responses via p38/MK2/TTP-mediated mRNA Stability
- (2013) Wanling Wu et al. MOLECULES
- The Polyphenol Fisetin Protects Bone by Repressing NF-κB and MKP-1-Dependent Signaling Pathways in Osteoclasts
- (2013) Laurent Léotoing et al. PLoS One
- Fisetin Inhibits Migration and Invasion of Human Cervical Cancer Cells by Down-Regulating Urokinase Plasminogen Activator Expression through Suppressing the p38 MAPK-Dependent NF-κB Signaling Pathway
- (2013) Ruey-Hwang Chou et al. PLoS One
- ERK/PP1a/PLB/SERCA2a and JNK Pathways Are Involved in Luteolin-Mediated Protection of Rat Hearts and Cardiomyocytes following Ischemia/Reperfusion
- (2013) Xin Wu et al. PLoS One
- JNK inhibition reduces apoptosis and neovascularization in a murine model of age-related macular degeneration
- (2013) H. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators
- (2013) B. P. Hubbard et al. SCIENCE
- Luteolin downregulates TLR4, TLR5, NF-κB and p-p38MAPK expression, upregulates the p-ERK expression, and protects rat brains against focal ischemia
- (2012) Huimin Qiao et al. BRAIN RESEARCH
- Inhibition of c-Jun N-terminal kinase and nuclear factor κ B pathways mediates fisetin-exerted anti-inflammatory activity in lipopolysccharide-treated RAW264.7 cells
- (2012) Sun-Chae Kim et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Control of Cytokine mRNA Expression by RNA-binding Proteins and microRNAs
- (2012) V. Palanisamy et al. JOURNAL OF DENTAL RESEARCH
- Negative regulation of inflammation by SIRT1
- (2012) Jun Xie et al. PHARMACOLOGICAL RESEARCH
- Small-Molecule Allosteric Activators of Sirtuins
- (2011) David A. Sinclair et al. Annual Review of Pharmacology and Toxicology
- Luteolin and chicoric acid synergistically inhibited inflammatory responses via inactivation of PI3K-Akt pathway and impairment of NF-κB translocation in LPS stimulated RAW 264.7 cells
- (2011) Chung Mu Park et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Luteolin attenuates the pulmonary inflammatory response involves abilities of antioxidation and inhibition of MAPK and NFκB pathways in mice with endotoxin-induced acute lung injury
- (2011) Min-Yung Kuo et al. FOOD AND CHEMICAL TOXICOLOGY
- UVB-induced DNA damage, generation of reactive oxygen species, and inflammation are effectively attenuated by the flavonoid luteolin in vitro and in vivo
- (2011) Ute Wölfle et al. FREE RADICAL BIOLOGY AND MEDICINE
- Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin
- (2011) Megumi Funakoshi-Tago et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Mapping the Transcriptional Machinery of the IL-8 Gene in Human Bronchial Epithelial Cells
- (2011) V. Bezzerri et al. JOURNAL OF IMMUNOLOGY
- Luteolin protects against reactive oxygen species-mediated cell death induced by zinc toxicity via the PI3K-Akt-NF-κB-ERK-dependent pathway
- (2011) Futao Zhou et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Effects of Luteolin on the Release of Nitric Oxide and Interleukin-6 by Macrophages Stimulated With Lipopolysaccharide FromPrevotella Intermedia
- (2011) Eun-Young Choi et al. JOURNAL OF PERIODONTOLOGY
- Celastrol regulates innate immunity response via NF-κB and Hsp70 in human retinal pigment epithelial cells
- (2011) Tuomas Paimela et al. PHARMACOLOGICAL RESEARCH
- Aging and disease: connections to sirtuins
- (2010) Gizem Donmez et al. AGING CELL
- Recent Research on Polyphenolics in Vision and Eye Health†
- (2010) Wilhelmina Kalt et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Luteolin inhibits cytokine expression in endotoxin/cytokine-stimulated microglia
- (2010) Tsung-Kuei Kao et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Luteolin Isolated from the Flowers of Lonicera japonica Suppresses Inflammatory Mediator Release by Blocking NF-κB and MAPKs Activation Pathways in HMC-1 Cells
- (2010) Ok-Hwa Kang et al. MOLECULES
- Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation
- (2009) Chieko Ando et al. FEBS LETTERS
- Constitutive and oxidative-stress-induced expression of VEGF in the RPE are differently regulated by different Mitogen-activated protein kinases
- (2009) Alexa Klettner et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells
- (2009) Chi-Sheng Chien et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Molecular inflammation: Underpinnings of aging and age-related diseases
- (2008) Hae Young Chung et al. AGEING RESEARCH REVIEWS
- MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cells
- (2008) Raphaël Roduit et al. APOPTOSIS
- 4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells
- (2008) Abha Sharma et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1
- (2008) S. Jang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation