Article
Nutrition & Dietetics
Chunsong Feng, Li Tian, Hui Hong, Quanyu Wang, Xin Zhan, Yongkang Luo, Yuqing Tan
Summary: This study evaluated the potential effect of whey protein hydrolysate (WPH) on the infant gut microbiome. The results showed that WPH had a positive modulation on the gut microbiota, increasing the production of short-chain fatty acids (SCFA) and promoting the growth of probiotics. This could benefit the energy balance and metabolism of infants.
Article
Fisheries
Bo-Paul Zhu, Jiancheng Zhou, Ziqin Wang, Yajun Hu, Minglang Cai, Linlin Yang, Jihong Dai, Yi Hu
Summary: The study investigates the effects of replacing fishmeal with enzymatic rice protein (RP) on the intestinal morphology, digestion, inflammation, and gut microbiota composition in juvenile channel catfish. The results show that a low dose of RP (2.5%) improves intestinal morphology and digestion, while a high dose (7.5%) disrupts gut microbiota homeostasis, resulting in intestinal mucosa damage and inflammatory response.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Immunology
Shimeng Huang, Xiaoping Rong, Meiling Liu, Zhongjun Liang, Yanqiang Geng, Xinyue Wang, Jianyun Zhang, Cheng Ji, Lihong Zhao, Qiugang Ma
Summary: This study investigated the effects of E. faecium on laying performance, egg quality, host metabolism, intestinal mucosal immunity, and gut microbiota of laying hens challenged with S. Enteritidis. The results showed that E. faecium supplementation improved egg production and shell thickness, regulated host lipid metabolism, enhanced immune functions, alleviated intestinal injuries, and improved gut microbial dysbiosis caused by S. Enteritidis infection.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Food Science & Technology
Chen-Jie Ling, Xiao-Fang Chen, Jia-Ying Xu, Gui-Ping Wang, Yan Wang, Yue Sun, Yun-Liang Li, Zhong-Xiao Wan, Xing Tong, Khemayanto Hidayat, Wan-Zhan Zhu, Li-Qiang Qin, Jing Yang
Summary: Whey protein hydrolysates have good prospects in weight management for middle-aged individuals by reducing energy intake, slowing down weight gain, improving blood lipids and glucose, and enhancing muscle antioxidant capacity.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Agriculture, Multidisciplinary
Fang Zhou, Yi-Long Li, Xin Zhang, Kun-Bo Wang, Jian-An Huang, Zhong-Hua Liu, Ming-Zhi Zhu
Summary: The study found that FBTP supplementation effectively reduced obesity in HFD-fed rats by improving intestinal oxidative stress and barrier function, as well as attenuating gut microbiota dysbiosis induced by HFD. Specific core microbes, including Akkermansia muciniphila, Alloprevotella, Bacteroides, and Faecalibaculum, were improved by FBTPs. The antiobesity effect of FBTPs was shown to be dependent on gut microbiota, as demonstrated by a fecal microbiota transplantation experiment.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Review
Fisheries
Francisco Vargas-Albores, Luis Rafael Martinez-Cordova, Adrian Hernandez-Mendoza, Francesco Cicala, Asuncion Lago-Leston, Marcel Martinez-Porchas
Summary: The intestinal microbiota plays a key role in fish health, affecting growth, mortality, and physiological functions. Therapeutic modulation strategies, including probiotics and prebiotics, can help alleviate dysbiosis and maintain a healthy gut microbiota in fish.
Article
Biochemistry & Molecular Biology
Valentine Renaud, Melanie Faucher, Marie-Julie Dubois, Genevieve Pilon, Thibault Varin, Andre Marette, Laurent Bazinet
Summary: Metabolic Syndrome (MetS) affects a large number of people globally and is a major health concern. The use of electrodialysis with ultrafiltration membrane (EDUF) has successfully produced bioactive peptides (BPs) from whey protein concentrate (WPC), and the fraction F3 has shown interesting DPP-IV inhibitory effects in vitro. This study aimed to evaluate the impact of each fraction on obesity models, revealing little physiological effect but changes in gut microbiota composition and functions in mice treated with F3.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Food Science & Technology
Xueyan Zhou, Xiaojing Tian, Li Song, Li Luo, Zhongren Ma, Fumei Zhang
Summary: This study investigated the effects of donkey whey protein and donkey whey hydrolysate on aging mice. The results showed that these substances could improve the body's aging condition, increase beneficial gut bacteria, and decrease harmful bacteria. Additionally, they positively influenced weight gain velocity, SOD activity, and thymus index. These findings contribute to a better understanding of the potential use of donkey whey protein and donkey whey hydrolysate in delaying aging.
FOOD SCIENCE & NUTRITION
(2023)
Article
Chemistry, Applied
Hye-Bin Lee, Young-Soo Kim, Ho -Young Park
Summary: This review discusses the relationship between the structural characteristics of pectic polysaccharides and the modulatory activity of gut microbiota. It also explores the health benefits of pectic polysaccharides on diet-induced obesity and intestinal health. Through regulating gut microbiota, pectic polysaccharides exert various beneficial biological effects.
CARBOHYDRATE POLYMERS
(2022)
Article
Nutrition & Dietetics
Mengzhen Han, Meina Zhang, Xiaowei Wang, Xue Bai, Tianli Yue, Zhenpeng Gao
Summary: The fermented cloudy apple juice rich in polyphenols showed potential to inhibit weight gain, reduce fat accumulation, and regulate blood lipid levels in obese mice. It achieved this by modifying the gut microbiota composition and improving intestinal tract health, as well as increasing the abundance of beneficial bacteria associated with short-chain fatty acids. These findings suggest that the fermented cloudy apple juice could be developed as a healthy food to prevent obesity and hyperglycemia.
Article
Chemistry, Applied
Tao Xu, Weisu Huang, Jiajia Liang, Yongheng Zhong, Qi Chen, Fan Jie, Baiyi Lu
Summary: The study found that cassava flour and potato flour are beneficial for normal rats, improving gut health and weight control. Compared with starch, these plant-based flours have a more significant effect on improving gut microbiota.
Review
Multidisciplinary Sciences
Sarmistha Mitra, Raju Dash, Amena Al Nishan, Sarmin Ummey Habiba, Il Soo Moon
Summary: This review examines the influence of the gut microbiota on neuronal development and neurodegenerative disorders, emphasizing the importance of understanding the balance between beneficial and harmful bacteria. It also highlights the potential therapeutic applications of targeting the gut microbiota population and its derivatives.
JOURNAL OF ADVANCED RESEARCH
(2023)
Article
Agriculture, Dairy & Animal Science
Min-Jin Kwak, Min-Young Park, Yong-Soon Choi, Junghwan Cho, Duleepa Pathiraja, Jonggun Kim, Hanbae Lee, In-Geol Choi, Kwang-Youn Whang
Summary: The experiment demonstrated that dietary supplementation of SPL significantly enhanced bird growth, improved feed efficiency, increased beneficial bacterial population, elevated butyrate concentration, strengthened gut barrier function, and exhibited anti-inflammatory effects.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Sisi Lin, Subhajit Mukherjee, Juanjuan Li, Weiliang Hou, Chao Pan, Jinyao Liu
Summary: The oral delivery of camouflaged probiotics can induce mucosal immune responses, regulate the gut microbiota, maintain gut homeostasis, and provide defense against external threats. Studies show that this approach effectively prevents intestinal barrier breakdown, bacterial translocation, and systemic inflammation.
Article
Pharmacology & Pharmacy
Xiaoyu Zhang, Junping Zheng, Nan Jiang, Guangjun Sun, Xinkun Bao, Mingwang Kong, Xue Cheng, Aizhen Lin, Hongtao Liu
Summary: This study demonstrates that lactulose can accelerate intestinal motility, suppress inflammatory responses, protect gut barrier, and improve constipation by repairing gut microbiota and enhancing the generation of intestinal metabolites.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Food Science & Technology
David Planes-Munoz, Carmen Frontela-Saseta, Gaspar Ros-Berruezo, Ruben Lopez-Nicolas
Summary: Overweight and obesity have become an epidemic worldwide, prompting an interest in studying satiety properties in foods. This research aimed to identify Mediterranean Diet foods with high satiating potential, and found that gazpacho had the highest satiating scores among the selected foods. More studies are needed to determine the best combination of ingredients in these Mediterranean recipes for enhancing human satiety.
Article
Food Science & Technology
Tamer M. El-Messery, Esmat Aly, Ruben Lopez-Nicolas, Teresa Sanchez-Moya, Gaspar Ros
Summary: The study utilized PCL microcapsules to encapsulate polyphenols extracted from olive leaves, demonstrating the potential of PCL microcapsules in formulating functional yogurt by effectively protecting and releasing polyphenols extract in the intestinal phase.
JOURNAL OF FOOD SCIENCE
(2021)
Review
Plant Sciences
Gema Nieto, Juana Fernandez-Lopez, Jose A. Perez-Alvarez, Rocio Penalver, Gaspar Ros, Manuel Viuda-Martos
Summary: Citrus fruits are extensively cultivated, with their co-products being considered as a valuable source of bioactive compounds for pharmaceutical, cosmetic, dietetic, and food industries. The food industry is seeking new and cost-effective sources of bioactive compounds to develop novel foods with health benefits.
Review
Agriculture, Multidisciplinary
Celia Carrillo, Gema Nieto, Lorena Martinez-Zamora, Gaspar Ros, Senem Kamiloglu, Paulo E. S. Munekata, Mirian Pateiro, Jose M. Lorenzo, Juana Fernandez-Lopez, Manuel Viuda-Martos, Jose Angel Perez-Alvarez, Francisco J. Barba
Summary: The increased industrial food production has led to a rise in food waste generation, which can be a valuable source of natural pigments. However, conventional methods for extracting these pigments are time-consuming, expensive, and unsustainable, and the pigments themselves are sensitive to high temperatures and prolonged processing times. Therefore, the recovery of natural pigments from food waste is important for both economic and environmental reasons.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Food Science & Technology
Lorena Martinez-Zamora, Rocio Penalver, Gaspar Ros, Gema Nieto
Summary: The olive tree is a widely cultivated crop in Mediterranean countries, rich in antioxidant compounds like hydroxytyrosol which offer health benefits. Hydroxytyrosol has anti-inflammatory, antioxidant, antimicrobial, and anticancer properties, making it a valuable preservative agent for meat. However, its unpleasant odor and flavor can be mitigated by using synthetic sources of hydroxytyrosol.
Article
Food Science & Technology
Rocio Penalver, Lorena Martinez-Zamora, Jose Manuel Lorenzo, Gaspar Ros, Gema Nieto
Summary: Moringa oleifera, a tree with antioxidant and anti-inflammatory properties, has been traditionally used as medicine. Research has found that it is rich in proteins and minerals, with high antioxidant capacity and bioaccessibility. It can be incorporated into the diet as a functional ingredient or fortifier due to its nutritional value.
Article
Nutrition & Dietetics
Luisma Sanchez-Siles, Sergio Roman, Juan F. Haro-Vicente, Maria Jose Bernal, Michelle Klerks, Gaspar Ros, Angel Gil
Summary: This study aimed to examine the acceptability of low-sugar complementary cereals in infants. The results showed that decreasing the sugar content in infant cereals did not affect infants' and parents' sensory evaluation, regardless of the infants' previous consumption of sweet cereals. This finding indicates an opportunity for the infant food industry to meet the demand of lowering sugar intake without compromising competitiveness in the market.
FRONTIERS IN NUTRITION
(2022)
Review
Biochemistry & Molecular Biology
Patricia Gonzalez, Pedro Lozano, Gaspar Ros, Francisco Solano
Summary: This review focuses on the complex relationship between oxidative stress, hyperglycemia, and diabetes and related metabolic disorders. The generation of reactive oxygen species (ROS) due to glucose metabolism and oxidative stress leads to hyperglycemia, insulin resistance, and cellular damage. Hyperglycemia further promotes glucose metabolism through various routes, exacerbating ROS formation and diabetes complications. Transcription factors NF-κB and Nrf2 play important roles in regulating pro-oxidant and antioxidant proteins, while the involvement of FoxO is controversial. This review summarizes the key factors linking hyperglycemia-enhanced glucose metabolic routes with ROS formation and emphasizes the role of transcription factors in maintaining a balance between pro-oxidant and antioxidant proteins.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Emergency Medicine
Jose Miguel Diez-Navarro, Cesar Leal-Costa, David Planes-Munoz, Maria Suarez-Cortes, Maria de los Angeles Castano-Molina, Alonso Molina-Rodriguez, Jose Luis Diaz-Agea
Summary: This study aimed to analyze and describe low- and high-power motorcycle accidents in Spain between 2014 and 2020, comparing these categories. The results showed that in Spain, male riders aged between 30 and 40 years old, using high-power motorcycles, with an A or A1 driver's license, and not wearing a helmet, had a 6.7 times higher risk of death in crossings and highways compared to moped users, and this risk increased to 4.89 times if a helmet was worn. During the COVID-19 pandemic, there was an increase in deaths within 24 hours after a high-power motorcycle accident, while the overall medical assistance provided was significantly reduced in 2019-2020.
EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
(2023)
Article
Food Science & Technology
Antonio Martinez-Martinez, David Planes-Munoz, Carmen Frontela-Saseta, Gaspar Ros, Ruben Lopez-Nicolas
Summary: This study evaluated the availability of iron and calcium as well as the satiety effect of different types of biscuits. The results showed differences in mineral content and availability between biscuit types, with the Maria type having a greater impact on food intake control.
Article
Food Science & Technology
Rocio Penalver, Gaspar Ros, Gema Nieto
Summary: The research aimed to develop gluten-free functional breads to meet the nutritional needs of celiac patients. Six different breads were made using pseudocereals, psyllium, and gluten-free sourdough, fortified with Moringa oleifera. The reformulated breads were found to have better nutritional properties and provide health benefits.
Article
Biotechnology & Applied Microbiology
Rocio Penalver, Gaspar Ros, Gema Nieto
Summary: Celiac patients often have nutritional deficiencies due to processed gluten-free foods that lack minerals typically found in wheat. This study examined the deficiencies of calcium, iron, fiber, folic acid, omega-3, vitamin B12, and vitamin D in these patients. Different formulations of gluten-free bread enriched with various extracts and minerals were studied for their nutritional composition and sensory qualities. The results showed that the bread enriched with synthetic olive extract had higher antioxidant capacity, antimicrobial capacity, fiber content, mineral content, and consumer acceptability compared to other bread samples. Overall, the study suggests that this enriched bread could be a suitable dietary choice for celiac patients.
FERMENTATION-BASEL
(2023)
Article
Nutrition & Dietetics
Rocio Penalver, Gaspar Ros, Lorena Martinez-Zamora, Gema Nieto
Summary: This study demonstrates a high prevalence of malnutrition, particularly obesity, among psychiatric patients, due to excessive intake of macronutrients and micronutrients in their daily menus.
NUTRICION HOSPITALARIA
(2022)
Letter
Public, Environmental & Occupational Health
J. Alfredo Martinez, Montana Camara, Rosa Ma Giner, Elena Gonzalez, Esther Lopez, Jordi Manes, Ma Puy Portillo, Magda Rafecas, Ramon Estruch, Gaspar Ros, Josep Antoni Tur, Ascension Marcos, Rodrigo San-Cristobal
REVISTA ESPANOLA DE SALUD PUBLICA
(2022)
Article
Nutrition & Dietetics
Lorena Martinez-Zamora, Rocio Penalver, Gaspar Ros, Gema Nieto
Summary: The study revealed that the eating habits of the university community in Murcia leans more towards meat and staple foods rather than vegetables, pulses, and fish. In terms of antioxidant capacity, lentil and chorizo stew showed the highest antioxidant capacity, while Spanish omelette showed the lowest. Therefore, consumption of fruits, vegetables, and legumes should be encouraged to enhance the antioxidant capacity of the diet.
NUTRICION HOSPITALARIA
(2021)
Article
Biochemistry & Molecular Biology
Davide Risso, Gillian Dunngalvin, Sameer Saxena, Andrea Doolan, Lisa Spence, Kavita Karnik
Summary: This study investigated the gastrointestinal tolerance of low-calorie sugar D-allulose in young children and found that it was well tolerated. It can be considered as a candidate for replacing added sugars with lower caloric content in commercially produced goods.
Article
Biochemistry & Molecular Biology
Xinying Suo, Anna Baggio, Nicoletta Pellegrini, Silvia Vincenzetti, Elena Vittadini
Summary: This study investigated the effects of shape, gluten, and structural breakdown on the starch digestibility and glycemic index of gluten-containing and gluten-free pasta. The results showed that mastication effort, shape, and gluten content had significant impacts on starch digestion and glycemic index, with gluten being the major factor affecting the amount of digested starch.
Article
Biochemistry & Molecular Biology
Xinnuo Hu, Yanjun Yang, Cuihua Chang, Junhua Li, Yujie Su, Luping Gu
Summary: Fish collagen was enzymatically hydrolyzed using alkaline, papain, and ginger protease. The addition of ginger protease increased the degree of hydrolysis and resulted in changes in the amino acid composition and molecular weight distribution of the peptides. Combined hydrolysis with ginger protease improved the ACE inhibitory activity of the sample but affected fibroblast proliferation activity.
Article
Biochemistry & Molecular Biology
Tong Nie, Xin Wang, Aqun Li, Anshan Shan, Jun Ma
Summary: This study investigated the mechanism by which hesperidin prevents nonalcoholic fatty liver disease (NAFLD) by modulating fatty acid beta oxidation. The results suggest that hesperidin promotes fatty acid beta oxidation by activating SIRT1/PGC1 alpha, thus improving NAFLD.
Article
Biochemistry & Molecular Biology
Li Li, Jing Zhao, Jinxue Wang, Qianqian Xiong, Xuechun Lin, Xiaolei Guo, Fan Peng, Wangqun Liang, Xuezhi Zuo, Chenjiang Ying
Summary: The daily administration of 10 g d-1 inulin-type fructans significantly reduced the circulating arsenic retention in end-stage renal disease by increasing the arsenic clearance rate through urine and dialysis. However, it was found to be ineffective for other trace elements.
Article
Biochemistry & Molecular Biology
Chuanchuan Wang, Weixuan Chen, Yishan Jiang, Xiao Xiao, Qianhui Zou, Jiarui Liang, Yu Zhao, Qianxu Wang, Tian Yuan, Rui Guo, Xuebo Liu, Zhigang Liu
Summary: Autism Spectrum Disorder (ASD) symptoms may be improved through modulation of gut microbiota. This study investigated the effects of a synbiotic treatment on an ASD-like mouse model, and found that it rectified social impairments, attenuated inflammatory cytokine expressions, protected gut barrier integrity, and altered gut microbiota composition. The synbiotic treatment elevated beneficial metabolites and upregulated genes associated with their synthesis. Overall, the synbiotic combination mitigated ASD-related social impairments through regulation of the gut-brain axis.
Review
Biochemistry & Molecular Biology
Chunli Kong, Caiping Duan, Yixuan Zhang, Yiying Wang, Zheng Yan, Sumei Zhou
Summary: This review critically discusses the physicochemical properties of bioactive molecules in kidney beans and focuses on the current knowledge of non-starch polysaccharide (NSP) structure and function on intestinal health and metabolism. It also provides suggestions for further investigation and development of NSPs as novel plant carbohydrate resources.
Article
Biochemistry & Molecular Biology
Fei Shen, Qianqian Wang, Sami Ullah, Ya Pan, Minjie Zhao, Jing Wang, Ming Chen, Fengqin Feng, Hao Zhong
Summary: This study investigated the peristalsis-promoting potential of Ligilactobacillus acidipiscis YJ5 and its underlying molecular mechanism in relieving constipation. The results showed that L. acidipiscis YJ5 intervention increased intestinal peristalsis in zebrafish and mouse models, reduced colonic aquaporin expression, repaired intestinal morphological damage, enhanced the colonic mucosal barrier, and reversed the gut microbiota structure. The positive effects of L. acidipiscis YJ5 were attributed to its metabolites such as malic acid and heliangin.
Article
Biochemistry & Molecular Biology
Zhuo Qu, Jiahui Tian, Jiachen Sun, Ying Shi, Jianqiang Yu, Wannian Zhang, Chunlin Zhuang
Summary: Smoking is the main risk factor for lung cancer, but garlic oil compound DATS shows potential as a chemopreventive agent. DATS can inhibit the carcinogenic effects of tobacco and regulate gut microbiota, as well as activate the PPAR-gamma pathway to suppress tumor growth.
Article
Biochemistry & Molecular Biology
Yanli Zhang, Jielun Hu, Yadong Zhong, Shuai Liu, Liandi Liu, Xinyi Mu, Chunhua Chen, Shenji Yang, Guohao Li, Duoduo Zhang, Xinru Huang, Jinrui Yang, Xiaojun Huang, Shuigen Bian, Shaoping Nie
Summary: The study found that different ratios of insoluble and soluble dietary fiber have distinct effects on gut microbiota and serum metabolites. Increasing the ratio of insoluble dietary fiber increases the relative abundance and acid production of specific bacterial genera, while increasing the ratio of soluble dietary fiber increases the diversity and relative abundance of other bacterial genera and regulates metabolic pathways.
Article
Biochemistry & Molecular Biology
Enhui Tang, Tong Hu, Zhaokang Jiang, Xiaojun Shen, Huan Lin, Haiyan Xian, Xinlan Wu
Summary: Isoquercitrin alleviates lipopolysaccharide-induced intestinal mucosal barrier damage in mice by inhibiting the TLR4/MyD88/NF-kappa B signaling pathway and modulating the intestinal flora.
Article
Biochemistry & Molecular Biology
Nesma A. Abd Elrazik, Sahar A. Helmy
Summary: This study found that betanin, the major pigment in red beetroot, has a protective effect against bleomycin-induced pulmonary fibrosis in rats. The protective effect may be attributed to the attenuation of the NLRP3/IL-1 beta/TGF-beta 1 signaling pathway and the suppression of the EMT process.
Article
Biochemistry & Molecular Biology
Sha Li, Longchen Shang, Yuanyuan Chen, Rong Song, Jing Li, Bin Li
Summary: A new form of konjac fiber was prepared that could instantly expand in contact with digestive fluid, inhibiting the digestion of food. The digestion regulation ability of the fiber was influenced by the freezing temperature used during preparation, with the fiber prepared at -20 degrees C showing the best performance in delaying gastric emptying and preventing intestinal starch hydrolysis.
Article
Biochemistry & Molecular Biology
Xian Xia, Jiangdong Li, Rui Liang, Yi Li, Xiaojuan Ma, Ying Yang, Daniel Lozano-Ojalvo
Summary: This study aimed to reduce the allergenicity of ovomucoid through unfolding-assisted glycation. The results showed that maltose glycation effectively reduced the IgG-binding capacity of the allergen. Unfolded and glycated ovomucoid exhibited enhanced antioxidant activity and metal ion chelating ability.