Annexin A6—A multifunctional scaffold in cell motility

Essential role of STX6 in esophageal squamous cell carcinoma growth and migration

(2016) Jin Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Annexins – insights from knockout mice

(2016) Thomas Grewal et al.   BIOLOGICAL CHEMISTRY

α-Spectrin and integrins act together to regulate actomyosin and columnarization, and to maintain a monolayered follicular epithelium

(2016) Bing Fu Ng et al.   DEVELOPMENT

Annexin A6 regulates interleukin-2-mediated T-cell proliferation

(2016) Rhea Cornely et al.   IMMUNOLOGY AND CELL BIOLOGY

An actin-dependent annexin complex mediates plasma membrane repair in muscle

(2016) Alexis R. Demonbreun et al.   JOURNAL OF CELL BIOLOGY

Autophagy in adhesion and migration

(2016) Candia M. Kenific et al.   JOURNAL OF CELL SCIENCE

Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness

(2016) Julie Leca et al.   JOURNAL OF CLINICAL INVESTIGATION

Emerging roles for vascular smooth muscle cell exosomes in calcification and coagulation

(2016) A. N. Kapustin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2

(2016) Nicola De Franceschi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2

(2016) Nicola De Franceschi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Modulation of focal adhesion constituents and their down-stream events by EGF: On the cross-talk of integrins and growth factor receptors

(2015) Philipp Eberwein et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ras nanoclusters: Versatile lipid-based signaling platforms

(2015) Yong Zhou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Evidence for annexin A6-dependent plasma membrane remodelling of lipid domains

(2015) Anna Alvarez-Guaita et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endocytic Trafficking of Integrins in Cell Migration

(2015) Nikki R. Paul et al.   CURRENT BIOLOGY

NEGotiating Cell Identity through Regulated Cytoplasmic Polyadenylation

(2015) Pradeep M. Joshi et al.   DEVELOPMENTAL CELL

Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration

(2015) Ana García-Melero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of cholesterol in SNARE-mediated trafficking on intracellular membranes

(2015) C. Enrich et al.   JOURNAL OF CELL SCIENCE

Signalling scaffolds and local organization of cellular behaviour

(2015) Lorene K. Langeberg et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Src defines a new pool of EGFR substrates

(2015) Nicole Michael et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Plasma membrane-associated platforms: Dynamic scaffolds that organize membrane-associated events

(2015) V. Astro et al.   Science Signaling

Emerging roles of exosomes during epithelial–mesenchymal transition and cancer progression

(2015) David W. Greening et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IQGAPs choreograph cellular signaling from the membrane to the nucleus

(2015) Jessica M. Smith et al.   TRENDS IN CELL BIOLOGY

Directional cell movement through tissues is controlled by exosome secretion

(2015) Bong Hwan Sung et al.   Nature Communications

The cross-talk of LDL-cholesterol with cell motility: Insights from the Niemann Pick Type C1 mutation and altered integrin trafficking

(2015) Monira Hoque et al.   Cell Adhesion & Migration

Src defines a new pool of EGFR substrates

(2015) Nicole Michael et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Predominant Rab-GTPase amplicons contributing to oral squamous cell carcinoma progression to metastasis

(2015) Sabrina Daniela da Silva et al.   Oncotarget

Ca2+Signaling in Cytoskeletal Reorganization, Cell Migration, and Cancer Metastasis

(2015) Feng-Chiao Tsai et al.   Biomed Research International

Plasma membrane-associated platforms: Dynamic scaffolds that organize membrane-associated events

(2015) V. Astro et al.   Science Signaling

Role of ErbB Receptors in Cancer Cell Migration and Invasion

(2015) Aline Appert-Collin et al.   Frontiers in Pharmacology

αII-Spectrin Regulates Invadosome Stability and Extracellular Matrix Degradation

(2015) Aurélie Ponceau et al.   PLoS One

Evaluation of a 4-protein serum biomarker panel-biglycan, annexin-A6, myeloperoxidase, and protein S100-A9 (B-AMP)-for the detection of esophageal adenocarcinoma

(2014) Ali H. Zaidi et al.   CANCER

Annexins — Scaffolds modulating PKC localization and signaling

(2014) Monira Hoque et al.   CELLULAR SIGNALLING

Caveolin-1 in Cell Migration and Metastasis

(2014) S. Nunez-Wehinger et al.   CURRENT MOLECULAR MEDICINE

Interdependent epidermal growth factor receptor signalling and trafficking

(2014) Sylwia Jones et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

SNARE-dependent interaction of Src, EGFR and  1 integrin regulates invadopodia formation and tumor cell invasion

(2014) K. C. Williams et al.   JOURNAL OF CELL SCIENCE

A novel interaction between Rab7b and actomyosin reveals a dual role in intracellular transport and cell migration

(2014) M. Borg et al.   JOURNAL OF CELL SCIENCE

SNAP23, Syntaxin4, and vesicle-associated membrane protein 7 (VAMP7) mediate trafficking of membrane type 1–matrix metalloproteinase (MT1-MMP) during invadopodium formation and tumor cell invasion

(2014) Karla C. Williams et al.   MOLECULAR BIOLOGY OF THE CELL

Supporting a Role for the GTPase Rab7 in Prostate Cancer Progression

(2014) Joshua J. Steffan et al.   PLoS One

Annexin A6 modifies muscular dystrophy by mediating sarcolemmal repair

(2014) K. A. Swaggart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation

(2014) Y. Lin-Moshier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholesterol Regulates Syntaxin 6 Trafficking at trans-Golgi Network Endosomal Boundaries

(2014) Meritxell Reverter et al.   Cell Reports

Late endosomal and lysosomal trafficking during integrin-mediated cell migration and invasion

(2013) Elena Rainero et al.   BIOESSAYS

LDL Cholesterol Recycles to the Plasma Membrane via a Rab8a-Myosin5b-Actin-Dependent Membrane Transport Route

(2013) Kristiina Kanerva et al.   DEVELOPMENTAL CELL

Reduced annexin A6 expression promotes the degradation of activated epidermal growth factor receptor and sensitizes invasive breast cancer cells to EGFR-targeted tyrosine kinase inhibitors

(2013) Rainelli B Koumangoye et al.   Molecular Cancer

Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells

(2013) Jonathan J Hulce et al.   NATURE METHODS

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics

(2013) Pedro M. R. Cruz et al.   Frontiers in Pharmacology

Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway

(2012) William A. Freed-Pastor et al.   CELL

In Vivo Imaging of Molecular Interactions at Damaged Sarcolemma

(2012) Urmas Roostalu et al.   DEVELOPMENTAL CELL

The Annexin A2/S100A10 System in Health and Disease: Emerging Paradigms

(2012) Nadia Hedhli et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Regulation of integrin endocytic recycling and chemotactic cell migration by syntaxin 6 and VAMP3 interaction

(2012) K. A. Riggs et al.   JOURNAL OF CELL SCIENCE

Unanchoring integrins in focal adhesions

(2012) Johanna Ivaska   NATURE CELL BIOLOGY

Annexin A6 is a scaffold for PKCα to promote EGFR inactivation

(2012) M Koese et al.   ONCOGENE

Annexin A6 Modulates Chick Cranial Neural Crest Cell Emigration

(2012) Chyong-Yi Wu et al.   PLoS One

Loss of Maternal Annexin A5 Increases the Likelihood of Placental Platelet Thrombosis and Foetal Loss

(2012) Hiroshi Ueki et al.   Scientific Reports

Interaction of annexin A6 with alpha actinin in cardiomyocytes

(2011) Sumita Mishra et al.   BMC CELL BIOLOGY

Annexins as organizers of cholesterol- and sphingomyelin-enriched membrane microdomains in Niemann-Pick type C disease

(2011) Magdalena Domon et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanisms of integrin activation and trafficking

(2011) Coert Margadant et al.   CURRENT OPINION IN CELL BIOLOGY

A palmitoylation switch mechanism regulates Rac1 function and membrane organization

(2011) Inmaculada Navarro-Lérida et al.   EMBO JOURNAL

Annexin VI is a mannose-6-phosphate-independent endocytic receptor for bovine β-glucuronidase

(2011) Alberto Ramírez-Mata et al.   EXPERIMENTAL CELL RESEARCH

Endothelial Cell Migration on Fibronectin Is Regulated by Syntaxin 6-mediated α5β1 Integrin Recycling

(2011) Ajit Tiwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tailored Protection against Plasmalemmal Injury by Annexins with Different Ca2+Sensitivities

(2011) Sarah Potez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration

(2011) Anja Mai et al.   JOURNAL OF CELL BIOLOGY

Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function

(2011) Meritxell Reverter et al.   MOLECULAR BIOLOGY OF THE CELL

Annexin A6—Linking Ca2+ signaling with cholesterol transport

(2010) Carlos Enrich et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Annexin A6 contributes to the invasiveness of breast carcinoma cells by influencing the organization and localization of functional focal adhesions

(2010) Amos M. Sakwe et al.   EXPERIMENTAL CELL RESEARCH

Annexin A6-regulator of the EGFR/Ras signalling pathway and cholesterol homeostasis

(2010) Thomas Grewal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Fetuin-A (α2HS-Glycoprotein) Is a Major Serum Adhesive Protein That Mediates Growth Signaling in Breast Tumor Cells

(2010) Amos M. Sakwe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of annexin A6 isoforms in catecholamine secretion by PC12 cells: Distinct influence on calcium response

(2010) Paulina Podszywalow-Bartnicka et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and function

(2010) B Alvarez-Moya et al.   ONCOGENE

Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions

(2010) C. Tu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

Intracellular Ca2+ operates a switch between repair and lysis of streptolysin O-perforated cells

(2009) E B Babiychuk et al.   CELL DEATH AND DIFFERENTIATION

Annexins — Modulators of EGF receptor signalling and trafficking

(2009) Thomas Grewal et al.   CELLULAR SIGNALLING

Plasma Membrane-associated Annexin A6 Reduces Ca2+Entry by Stabilizing the Cortical Actin Cytoskeleton

(2009) Katia Monastyrskaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells

(2009) A. Tomar et al.   JOURNAL OF CELL SCIENCE

Inactivation of Ras by p120GAP via Focal Adhesion Kinase Dephosphorylation Mediates RGMa-Induced Growth Cone Collapse

(2009) M. Endo et al.   JOURNAL OF NEUROSCIENCE

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

Integrins: masters and slaves of endocytic transport

(2009) Patrick T. Caswell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Caveolin-1 in tumor progression: the good, the bad and the ugly

(2008) Jacky G. Goetz et al.   CANCER AND METASTASIS REVIEWS

Capns1, a new binding partner of RasGAP-SH3 domain in K-RasV12 oncogenic cells: Modulation of cell survival and migration

(2008) Perayot Pamonsinlapatham et al.   CELLULAR SIGNALLING

Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

(2008) Sara Sigismund et al.   DEVELOPMENTAL CELL

Interaction between S100A8/A9 and Annexin A6 Is Involved in the Calcium-induced Cell Surface Exposition of S100A8/A9

(2008) Günther Bode et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Annexin A6-induced Inhibition of Cytoplasmic Phospholipase A2Is Linked to Caveolin-1 Export from the Golgi

(2008) Laia Cubells et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular cholesterol trafficking and compartmentalization

(2008) Elina Ikonen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Annexin A6 inhibits Ras signalling in breast cancer cells

(2008) S Vilá de Muga et al.   ONCOGENE

Annexins sense changes in intracellular pH during hypoxia

(2007) Katia Monastyrskaya et al.   BIOCHEMICAL JOURNAL