VEGF-A121a binding to Neuropilins – A concept revisited

Expanding the 3-O-Sulfate Proteome—Enhanced Binding of Neuropilin-1 to 3-O-Sulfated Heparan Sulfate Modulates Its Activity

(2016) Bryan E. Thacker et al.   ACS Chemical Biology

VEGFR-2 conformational switch in response to ligand binding

(2016) Sarvenaz Sarabipour et al.   eLife

Cysteines in the neuropilin-2 MAM domain modulate receptor homooligomerization and signal transduction

(2015) Rachael Barton et al.   BIOPOLYMERS

Neuropilin Functions as an Essential Cell Surface Receptor

(2015) Hou-Fu Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity

(2015) Madelane Teran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form

(2015) Matthew W. Parker et al.   STRUCTURE

Evidence for New Homotypic and Heterotypic Interactions between Transmembrane Helices of Proteins Involved in Receptor Tyrosine Kinase and Neuropilin Signaling

(2014) Paul Sawma et al.   JOURNAL OF MOLECULAR BIOLOGY

Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding

(2014) Maria V Gelfand et al.   eLife

Extracellular regulation of VEGF: Isoforms, proteolysis, and vascular patterning

(2013) Prakash Vempati et al.   CYTOKINE & GROWTH FACTOR REVIEWS

New prospects in the roles of the C-terminal domains of VEGF-A and their cooperation for ligand binding, cellular signaling and vessels formation

(2012) Romain Delcombel et al.   ANGIOGENESIS

Structural Basis for Selective Vascular Endothelial Growth Factor-A (VEGF-A) Binding to Neuropilin-1

(2012) Matthew W. Parker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Selective VEGF-A Binding by Neuropilin-1 Reveals a Basis for Specific Ligand Inhibition

(2012) Matthew W. Parker et al.   PLoS One

The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis

(2012) Melissa J. Cudmore et al.   Nature Communications

VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation

(2011) Birger Herzog et al.   MOLECULAR BIOLOGY OF THE CELL

Overexpression of VEGF189 in breast cancer cells induces apoptosis via NRP1 under stress conditions

(2011) Nadejda Vintonenko et al.   Cell Adhesion & Migration

Heparan Sulfate Regulates VEGF165- and VEGF121-mediated Vascular Hyperpermeability

(2010) Ding Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure–function analysis of VEGF receptor activation and the role of coreceptors in angiogenic signaling

(2009) Felix S. Grünewald et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration

(2009) T. Teesalu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Single Transmembrane Domains of Human Receptor Tyrosine Kinases Encode Self-Interactions

(2009) C. Finger et al.   Science Signaling

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

(2008) H. Kawamura et al.   BLOOD

Vascular Endothelial Growth Factor (VEGF)-A165b Is a Weak In vitro Agonist for VEGF Receptor-2 Due to Lack of Coreceptor Binding and Deficient Regulation of Kinase Activity

(2008) H. Kawamura et al.   CANCER RESEARCH

Neuropilin-1-VEGFR-2 Complexing Requires the PDZ-binding Domain of Neuropilin-1

(2008) Claudia Prahst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors

(2008) D. G. Nowak et al.   JOURNAL OF CELL SCIENCE

Transmembrane Domain Interactions Control Biological Functions of Neuropilin-1

(2007) Lise Roth et al.   MOLECULAR BIOLOGY OF THE CELL