VEGFR-2 conformational switch in response to ligand binding

Fully quantified spectral imaging reveals in vivo membrane protein interactions

(2016) Christopher King et al.   Integrative Biology

Mechanism of FGF receptor dimerization and activation

(2016) Sarvenaz Sarabipour et al.   Nature Communications

Analytical characterization of plasma membrane-derived vesicles produced via osmotic and chemical vesiculation

(2015) Sarvenaz Sarabipour et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Effect of Thanatophoric Dysplasia Type I Mutations on FGFR3 Dimerization

(2015) Nuala Del Piccolo et al.   BIOPHYSICAL JOURNAL

Unliganded Fibroblast Growth Factor Receptor 1 Forms Density-independent Dimers

(2015) Laëtitia Comps-Agrar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FGFR3 Unliganded Dimer Stabilization by the Juxtamembrane Domain

(2015) Sarvenaz Sarabipour et al.   JOURNAL OF MOLECULAR BIOLOGY

Site-Specific Phosphorylation of VEGFR2 Is Mediated by Receptor Trafficking: Insights from a Computational Model

(2015) Lindsay Wendel Clegg et al.   PLoS Computational Biology

Uninduced high-yield bacterial expression of fluorescent proteins

(2014) Sarvenaz Sarabipour et al.   ANALYTICAL BIOCHEMISTRY

The FRET Signatures of Noninteracting Proteins in Membranes: Simulations and Experiments

(2014) Christopher King et al.   BIOPHYSICAL JOURNAL

Functional and structural characterization of the kinase insert and the carboxy terminal domain in VEGF receptor 2 activation

(2014) Sandro Manni et al.   FASEB JOURNAL

Structural and Functional Characterization of Alternative Transmembrane Domain Conformations in VEGF Receptor 2 Activation

(2014) Sandro Manni et al.   STRUCTURE

How IGF-1 activates its receptor

(2014) Jennifer M Kavran et al.   eLife

Chronic inhibition of tumor cell-derived VEGF enhances the malignant phenotype of colorectal cancer cells

(2013) Naoko Yamagishi et al.   BMC CANCER

Architecture and Membrane Interactions of the EGF Receptor

(2013) Anton Arkhipov et al.   CELL

Conformational Coupling across the Plasma Membrane in Activation of the EGF Receptor

(2013) Nicholas F. Endres et al.   CELL

Extracellular regulation of VEGF: Isoforms, proteolysis, and vascular patterning

(2013) Prakash Vempati et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Consequences of membrane topography

(2013) Ingela Parmryd et al.   FEBS Journal

Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer

(2013) Sampurna Chatterjee et al.   JOURNAL OF CLINICAL INVESTIGATION

Structure of FGFR3 Transmembrane Domain Dimer: Implications for Signaling and Human Pathologies

(2013) Eduard V. Bocharov et al.   STRUCTURE

Production of Plasma Membrane Vesicles with Chloride Salts and Their Utility as a Cell Membrane Mimetic for Biophysical Characterization of Membrane Protein Interactions

(2012) Nuala Del Piccolo et al.   ANALYTICAL CHEMISTRY

Unraveling the influence of endothelial cell density on VEGF-A signaling

(2012) L. Napione et al.   BLOOD

Inhibition of Basal FGF Receptor Signaling by Dimeric Grb2

(2012) Chi-Chuan Lin et al.   CELL

Targeting Extracellular Domains D4 and D7 of Vascular Endothelial Growth Factor Receptor 2 Reveals Allosteric Receptor Regulatory Sites

(2012) C. A. C. Hyde et al.   MOLECULAR AND CELLULAR BIOLOGY

Expression of VEGF Receptors on Endothelial Cells in Mouse Skeletal Muscle

(2012) Princess I. Imoukhuede et al.   PLoS One

Grb2, a Double-Edged Sword of Receptor Tyrosine Kinase Signaling

(2012) A. A. Belov et al.   Science Signaling

Signal transduction by vascular endothelial growth factor receptors

(2011) Sina Koch et al.   BIOCHEMICAL JOURNAL

Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output

(2011) K. Ballmer-Hofer et al.   BLOOD

Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization

(2011) M. S. Brozzo et al.   BLOOD

Structural analysis of vascular endothelial growth factor receptor-2/ligand complexes by small-angle X-ray solution scattering

(2011) Kaisa Kisko et al.   FASEB JOURNAL

ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding

(2011) Shalini T Low-Nam et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural determinants of vascular endothelial growth factor-D receptor binding and specificity

(2010) V.-M. Leppanen et al.   BLOOD

Vascular Endothelial Growth Factor Receptors VEGFR-2 and VEGFR-3 Are Localized Primarily to the Vasculature in Human Primary Solid Cancers

(2010) N. R. Smith et al.   CLINICAL CANCER RESEARCH

Quantification and cell-to-cell variation of vascular endothelial growth factor receptors

(2010) P.I. Imoukhuede et al.   EXPERIMENTAL CELL RESEARCH

Measuring the Energetics of Membrane Protein Dimerization in Mammalian Membranes

(2010) Lirong Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spatial control of EGF receptor activation by reversible dimerization on living cells

(2010) Inhee Chung et al.   NATURE

Plasma membrane topography and interpretation of single-particle tracks

(2010) Jeremy Adler et al.   NATURE METHODS

Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling

(2010) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems biology of pro-angiogenic therapies targeting the VEGF system

(2010) Feilim Mac Gabhann et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Receptor tyrosine kinase transmembrane domains

(2010) Edwin Li et al.   Cell Adhesion & Migration

Phosphorylation of endothelial nitric oxide synthase by atypical PKC  contributes to angiopoietin-1-dependent inhibition of VEGF-induced endothelial permeability in vitro

(2009) M. Oubaha et al.   BLOOD

Multiscale models of angiogenesis

(2009) A.A. Qutub et al.   IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE

Infantile Hemangioma

(2009) Eileen Boye et al.   JOURNAL OF CRANIOFACIAL SURGERY

Quantitative Measurements of Protein Interactions in a Crowded Cellular Environment

(2008) Edwin Li et al.   ANALYTICAL CHEMISTRY

Spatial Structure of the Dimeric Transmembrane Domain of the Growth Factor Receptor ErbB2 Presumably Corresponding to the Receptor Active State

(2008) Eduard V. Bocharov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Cell Growth and VEGF Expression in Ovarian Cancer Cells by Flavonoids

(2008) Haitao Luo et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL