Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging

Multiplexed Intact-Tissue Transcriptional Analysis at Cellular Resolution

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Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release

(2016) Nazila Kamaly et al.   CHEMICAL REVIEWS

Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy

(2016) Christina Pfirschke et al.   IMMUNITY

Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues

(2016) Taeyun Ku et al.   NATURE BIOTECHNOLOGY

Optimizing probes to image cleared tissue

(2016) Vivien Marx   NATURE METHODS

The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas

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Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression

(2015) Eunha Kim et al.   BIOCONJUGATE CHEMISTRY

Macrophages and Therapeutic Resistance in Cancer

(2015) Brian Ruffell et al.   CANCER CELL

Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems

(2015) Evan Murray et al.   CELL

Clarifying Tissue Clearing

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The interaction of anticancer therapies with tumor-associated macrophages

(2015) Alberto Mantovani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

ScaleS: an optical clearing palette for biological imaging

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Imaging the beating heart in the mouse using intravital microscopy techniques

(2015) Claudio Vinegoni et al.   Nature Protocols

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

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Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization

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Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

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Noninvasive imaging of immune responses

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Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle

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Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug

(2015) Miles A. Miller et al.   Nature Communications

Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA

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Molecular and immune heterogeneity in synchronous melanoma metastases

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Tissue Optical Clearing, Three-Dimensional Imaging, and Computer Morphometry in Whole Mouse Lungs and Human Airways

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The journey from stem cell to macrophage

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iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging

(2014) Nicolas Renier et al.   CELL

Spatial–temporal FUCCI imaging of each cell in a tumor demonstrates locational dependence of cell cycle dynamics and chemoresponsiveness

(2014) Shuya Yano et al.   CELL CYCLE

Red Si–rhodamine drug conjugates enable imaging in GFP cells

(2014) Eunha Kim et al.   CHEMICAL COMMUNICATIONS

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

(2014) Matthew M. Gubin et al.   NATURE

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

Imaging macrophages with nanoparticles

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Fluorogenic probes for live-cell imaging of the cytoskeleton

(2014) Gražvydas Lukinavičius et al.   NATURE METHODS

Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin

(2014) A. M. Laughney et al.   Science Translational Medicine

Functional Relationship between Tumor-Associated Macrophages and Macrophage Colony-Stimulating Factor as Contributors to Cancer Progression

(2014) Damya Laoui et al.   Frontiers in Immunology

Macrophage Regulation of Tumor Responses to Anticancer Therapies

(2013) Michele De Palma et al.   CANCER CELL

Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy

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Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

CLARITY for mapping the nervous system

(2013) Kwanghun Chung et al.   NATURE METHODS

Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor

(2013) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunotype and Immunohistologic Characteristics of Tumor-Infiltrating Immune Cells Are Associated with Clinical Outcome in Metastatic Melanoma

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Computed Tomography Imaging of Primary Lung Cancer in Mice Using a Liposomal-Iodinated Contrast Agent

(2012) Cristian T. Badea et al.   PLoS One

Dextran-Coated Iron Oxide Nanoparticles: A Versatile Platform for Targeted Molecular Imaging, Molecular Diagnostics, and Therapy

(2011) Carlos Tassa et al.   ACCOUNTS OF CHEMICAL RESEARCH

Does the cell number 109still really fit one gram of tumor tissue?

(2011) Ugo Del Monte   CELL CYCLE

MRI of Tumor-Associated Macrophages with Clinically Applicable Iron Oxide Nanoparticles

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A Systems Approach for Tumor Pharmacokinetics

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Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

(2011) David G. DeNardo et al.   Cancer Discovery

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

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Stabilized imaging of immune surveillance in the mouse lung

(2010) Mark R Looney et al.   NATURE METHODS

Ferumoxytol as an Intravenous Iron Replacement Therapy in Hemodialysis Patients

(2009) R. Provenzano et al.   Clinical Journal of the American Society of Nephrology

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

(2009) Michel DuPage et al.   Nature Protocols

Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation

(2008) Virna Cortez-Retamozo et al.   JOURNAL OF CLINICAL INVESTIGATION

Optical phase conjugation for turbidity suppression in biological samples

(2008) Zahid Yaqoob et al.   Nature Photonics