Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

(2017) M. Carola Zillikens et al.   Nature Communications

Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication

(2016) Gerard Karsenty et al.   CELL

Evaluating the contribution of genetics and familial shared environment to common disease using the UK Biobank

(2016) María Muñoz et al.   NATURE GENETICS

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures

(2016) Unnur Styrkarsdottir et al.   Nature Communications

miR-33-5p, a novel mechano-sensitive microRNA promotes osteoblast differentiation by targeting Hmga2

(2016) Han Wang et al.   Scientific Reports

MiR-138 promotes smooth muscle cells proliferation and migration in db/db mice through down-regulation of SIRT1

(2015) Juan Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bone and muscle: Interactions beyond mechanical

(2015) Marco Brotto et al.   BONE

Two Rare Mutations in theCOL1A2Gene Associate With Low Bone Mineral Density and Fractures in Iceland

(2015) Unnur Styrkarsdottir et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture

(2015) Hou‐Feng Zheng et al.   NATURE

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data

(2014) Thomas W. Winkler et al.   BIOINFORMATICS

High-Resolution Genome Screen for Bone Mineral Density in Heterogeneous Stock Rat

(2014) Imranul Alam et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Lean mass as a total mediator of the influence of muscular fitness on bone health in schoolchildren: a mediation analysis

(2014) Ana Torres-Costoso et al.   JOURNAL OF SPORTS SCIENCES

A Comparison of Multivariate Genome-Wide Association Methods

(2014) Tessel E. Galesloot et al.   PLoS One

Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment

(2014) John P. Kemp et al.   PLoS Genetics

Estimation and Partition of Heritability in Human Populations Using Whole-Genome Analysis Methods

(2013) Anna A.E. Vinkhuyzen et al.   Annual Review of Genetics

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

(2013) Lei Zhang et al.   HUMAN MOLECULAR GENETICS

Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

(2013) Unnur Styrkarsdottir et al.   NATURE

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways

(2013) Anindya Bhattacharya et al.   NUCLEIC ACIDS RESEARCH

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits

(2013) Noah Zaitlen et al.   PLoS Genetics

Estimating Kinship in Admixed Populations

(2012) Timothy Thornton et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

(2012) S.H. Lee et al.   BIOINFORMATICS

Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study

(2012) Yan-Fang Guo et al.   HUMAN GENETICS

Meta-analysis of genome-wide studies identifiesWNT16andESR1SNPs associated with bone mineral density in premenopausal women

(2012) Daniel L Koller et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

SREBP-1 Transcription Factors Regulate Skeletal Muscle Cell Size by Controlling Protein Synthesis through Myogenic Regulatory Factors

(2012) Kevin Dessalle et al.   PLoS One

Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the WNT16 Locus

(2012) Carolina Medina-Gomez et al.   PLoS Genetics

WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk

(2012) Hou-Feng Zheng et al.   PLoS Genetics

Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle

(2011) Andrie Koutsoulidou et al.   BMC DEVELOPMENTAL BIOLOGY

Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis

(2011) Jing Gong et al.   HUMAN MUTATION

Molecular disease map of bone characterizing the postmenopausal osteoporosis phenotype

(2011) Rune Jemtland et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Prediction of Appendicular Skeletal and Fat Mass in Children: Excellent Concordance of Dual-energy X-ray Absorptiometry and Magnetic Resonance Imaging

(2011) P. Bridge et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo

(2011) T. Eskildsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Web-Based Genome-Wide Association Study Identifies Two Novel Loci and a Substantial Genetic Component for Parkinson's Disease

(2011) Chuong B. Do et al.   PLoS Genetics

Genome-Wide Association Study Using Extreme Truncate Selection Identifies Novel Genes Affecting Bone Mineral Density and Fracture Risk

(2011) Emma L. Duncan et al.   PLoS Genetics

Genetics of Osteoporosis

(2010) Stuart H. Ralston et al.   ENDOCRINE REVIEWS

Inhibition of Proprotein Convertase SKI-1 Blocks Transcription of Key Extracellular Matrix Genes Regulating Osteoblastic Mineralization

(2010) Jeff P. Gorski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An investigation into the relationship between soft tissue body composition and bone mineral density in a young adult twin sample

(2010) Leonie H Bogl et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Dysregulation and cellular mislocalization of specific miRNAs in myotonic dystrophy type 1

(2010) Riccardo Perbellini et al.   NEUROMUSCULAR DISORDERS

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

Eight genes are highly associated with BMD variation in postmenopausal Caucasian women

(2009) Sjur Reppe et al.   BONE

Is Bone's Response to Mechanical Signals Dominated by Muscle Forces?

(2009) ALEXANDER G. ROBLING   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

A New Role for Sterol Regulatory Element Binding Protein 1 Transcription Factors in the Regulation of Muscle Mass and Muscle Cell Differentiation

(2009) V. Lecomte et al.   MOLECULAR AND CELLULAR BIOLOGY

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

(2009) Fernando Rivadeneira et al.   NATURE GENETICS

Smith–Magenis syndrome

(2008) Sarah H Elsea et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Heritability of body size and muscle strength in young adulthood: a study of one million Swedish men

(2008) Karri Silventoinen et al.   GENETIC EPIDEMIOLOGY

Genetics of the Musculoskeletal System: A Pleiotropic Approach

(2008) David Karasik et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study

(2008) JB Richards et al.   LANCET

Tom1l2 hypomorphic mice exhibit increased incidence of infections and tumors and abnormal immunologic response

(2008) Santhosh Girirajan et al.   MAMMALIAN GENOME