Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
出版年份 2017 全文链接
标题
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
作者
关键词
-
出版物
Nature Communications
Volume 8, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-07-18
DOI
10.1038/s41467-017-00108-3
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
- (2017) M. Carola Zillikens et al. Nature Communications
- Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication
- (2016) Gerard Karsenty et al. CELL
- Evaluating the contribution of genetics and familial shared environment to common disease using the UK Biobank
- (2016) María Muñoz et al. NATURE GENETICS
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures
- (2016) Unnur Styrkarsdottir et al. Nature Communications
- miR-33-5p, a novel mechano-sensitive microRNA promotes osteoblast differentiation by targeting Hmga2
- (2016) Han Wang et al. Scientific Reports
- MiR-138 promotes smooth muscle cells proliferation and migration in db/db mice through down-regulation of SIRT1
- (2015) Juan Xu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Bone and muscle: Interactions beyond mechanical
- (2015) Marco Brotto et al. BONE
- Two Rare Mutations in theCOL1A2Gene Associate With Low Bone Mineral Density and Fractures in Iceland
- (2015) Unnur Styrkarsdottir et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture
- (2015) Hou‐Feng Zheng et al. NATURE
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- Predicting effective microRNA target sites in mammalian mRNAs
- (2015) Vikram Agarwal et al. eLife
- EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data
- (2014) Thomas W. Winkler et al. BIOINFORMATICS
- High-Resolution Genome Screen for Bone Mineral Density in Heterogeneous Stock Rat
- (2014) Imranul Alam et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Lean mass as a total mediator of the influence of muscular fitness on bone health in schoolchildren: a mediation analysis
- (2014) Ana Torres-Costoso et al. JOURNAL OF SPORTS SCIENCES
- A Comparison of Multivariate Genome-Wide Association Methods
- (2014) Tessel E. Galesloot et al. PLoS One
- Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment
- (2014) John P. Kemp et al. PLoS Genetics
- Estimation and Partition of Heritability in Human Populations Using Whole-Genome Analysis Methods
- (2013) Anna A.E. Vinkhuyzen et al. Annual Review of Genetics
- Multistage genome-wide association meta-analyses identified two new loci for bone mineral density
- (2013) Lei Zhang et al. HUMAN MOLECULAR GENETICS
- Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits
- (2013) Unnur Styrkarsdottir et al. NATURE
- Systematic identification of trans eQTLs as putative drivers of known disease associations
- (2013) Harm-Jan Westra et al. NATURE GENETICS
- miRBase: annotating high confidence microRNAs using deep sequencing data
- (2013) Ana Kozomara et al. NUCLEIC ACIDS RESEARCH
- PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways
- (2013) Anindya Bhattacharya et al. NUCLEIC ACIDS RESEARCH
- The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
- (2013) Danielle Welter et al. NUCLEIC ACIDS RESEARCH
- Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits
- (2013) Noah Zaitlen et al. PLoS Genetics
- Estimating Kinship in Admixed Populations
- (2012) Timothy Thornton et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood
- (2012) S.H. Lee et al. BIOINFORMATICS
- Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study
- (2012) Yan-Fang Guo et al. HUMAN GENETICS
- Meta-analysis of genome-wide studies identifiesWNT16andESR1SNPs associated with bone mineral density in premenopausal women
- (2012) Daniel L Koller et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Topological domains in mammalian genomes identified by analysis of chromatin interactions
- (2012) Jesse R. Dixon et al. NATURE
- Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
- (2012) Karol Estrada et al. NATURE GENETICS
- SREBP-1 Transcription Factors Regulate Skeletal Muscle Cell Size by Controlling Protein Synthesis through Myogenic Regulatory Factors
- (2012) Kevin Dessalle et al. PLoS One
- Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the WNT16 Locus
- (2012) Carolina Medina-Gomez et al. PLoS Genetics
- WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk
- (2012) Hou-Feng Zheng et al. PLoS Genetics
- Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle
- (2011) Andrie Koutsoulidou et al. BMC DEVELOPMENTAL BIOLOGY
- Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis
- (2011) Jing Gong et al. HUMAN MUTATION
- Molecular disease map of bone characterizing the postmenopausal osteoporosis phenotype
- (2011) Rune Jemtland et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Prediction of Appendicular Skeletal and Fat Mass in Children: Excellent Concordance of Dual-energy X-ray Absorptiometry and Magnetic Resonance Imaging
- (2011) P. Bridge et al. JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
- HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
- (2011) L. D. Ward et al. NUCLEIC ACIDS RESEARCH
- MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo
- (2011) T. Eskildsen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Web-Based Genome-Wide Association Study Identifies Two Novel Loci and a Substantial Genetic Component for Parkinson's Disease
- (2011) Chuong B. Do et al. PLoS Genetics
- Genome-Wide Association Study Using Extreme Truncate Selection Identifies Novel Genes Affecting Bone Mineral Density and Fracture Risk
- (2011) Emma L. Duncan et al. PLoS Genetics
- Genetics of Osteoporosis
- (2010) Stuart H. Ralston et al. ENDOCRINE REVIEWS
- Inhibition of Proprotein Convertase SKI-1 Blocks Transcription of Key Extracellular Matrix Genes Regulating Osteoblastic Mineralization
- (2010) Jeff P. Gorski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An investigation into the relationship between soft tissue body composition and bone mineral density in a young adult twin sample
- (2010) Leonie H Bogl et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Dysregulation and cellular mislocalization of specific miRNAs in myotonic dystrophy type 1
- (2010) Riccardo Perbellini et al. NEUROMUSCULAR DISORDERS
- MiR-33 Contributes to the Regulation of Cholesterol Homeostasis
- (2010) K. J. Rayner et al. SCIENCE
- Eight genes are highly associated with BMD variation in postmenopausal Caucasian women
- (2009) Sjur Reppe et al. BONE
- Is Bone's Response to Mechanical Signals Dominated by Muscle Forces?
- (2009) ALEXANDER G. ROBLING MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- A New Role for Sterol Regulatory Element Binding Protein 1 Transcription Factors in the Regulation of Muscle Mass and Muscle Cell Differentiation
- (2009) V. Lecomte et al. MOLECULAR AND CELLULAR BIOLOGY
- Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
- (2009) Fernando Rivadeneira et al. NATURE GENETICS
- Smith–Magenis syndrome
- (2008) Sarah H Elsea et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Heritability of body size and muscle strength in young adulthood: a study of one million Swedish men
- (2008) Karri Silventoinen et al. GENETIC EPIDEMIOLOGY
- Genetics of the Musculoskeletal System: A Pleiotropic Approach
- (2008) David Karasik et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study
- (2008) JB Richards et al. LANCET
- Tom1l2 hypomorphic mice exhibit increased incidence of infections and tumors and abnormal immunologic response
- (2008) Santhosh Girirajan et al. MAMMALIAN GENOME
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started