Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

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Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5′-flanking region ofPRDM16gene associated with lean body mass

(2014) Tomohiko Urano et al.   AGING CELL

Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits

(2014) Joseph K. Pickrell   AMERICAN JOURNAL OF HUMAN GENETICS

The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates

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Obesity-associated variants within FTO form long-range functional connections with IRX3

(2014) Scott Smemo et al.   NATURE

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

A Genome-Wide Association Study in American Indians Implicates DNER as a Susceptibility Locus for Type 2 Diabetes

(2013) R. L. Hanson et al.   DIABETES

Relationships of 35 lower limb muscles to height and body mass quantified using MRI

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A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

(2013) Keri L Monda et al.   NATURE GENETICS

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

(2013) Sonja I Berndt et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

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Association of FTO gene variants with body composition in UK twins

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Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study

(2012) Yan-Fang Guo et al.   HUMAN GENETICS

FTO genotype is associated with phenotypic variability of body mass index

(2012) Jian Yang et al.   NATURE

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

Chromatin marks identify critical cell types for fine mapping complex trait variants

(2012) Gosia Trynka et al.   NATURE GENETICS

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

(2012) Alisa K Manning et al.   NATURE GENETICS

ChromHMM: automating chromatin-state discovery and characterization

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Effects of aerobic vs. resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT

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The type 2 diabetes and insulin-resistance locus near IRS1 is a determinant of HDL cholesterol and triglycerides levels among diabetic subjects

(2011) Rajani Sharma et al.   ATHEROSCLEROSIS

Transethnic meta-analysis of genomewide association studies

(2011) Andrew P. Morris   GENETIC EPIDEMIOLOGY

A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort

(2011) D. M. Greenawalt et al.   GENOME RESEARCH

Genome-wide association study of copy number variation identified gremlin1 as a candidate gene for lean body mass

(2011) Rong Hai et al.   JOURNAL OF HUMAN GENETICS

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

(2011) Tuomas O Kilpeläinen et al.   NATURE GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry

(2011) Amidou N'Diaye et al.   PLoS Genetics

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The downstream effects of vitamin D in spermatozoa needs further study

(2010) B. Yang et al.   HUMAN REPRODUCTION

Association between fat intake, physical activity and mortality depending on genetic variation in FTO

(2010) E Sonestedt et al.   INTERNATIONAL JOURNAL OF OBESITY

Versican Facilitates Chondrocyte Differentiation and Regulates Joint Morphogenesis

(2010) Kanyamas Choocheep et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

(2010) Cathy E Elks et al.   NATURE GENETICS

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

The Fat Mass and Obesity Associated Gene FTO Functions in the Brain to Regulate Postnatal Growth in Mice

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Genome-wide Association and Replication Studies Identified TRHR as an Important Gene for Lean Body Mass

(2009) Xiao-Gang Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GWAF: an R package for genome-wide association analyses with family data

(2009) Ming-Huei Chen et al.   BIOINFORMATICS

Population genomics in a disease targeted primary cell model

(2009) E. Grundberg et al.   GENOME RESEARCH

Differences in fat and muscle mass associated with a functional human polymorphism in a post-transcriptionalBMP2gene regulatory element

(2009) Joseph M. Devaney et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

(2009) Cecilia M. Lindgren et al.   PLoS Genetics

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Sex-specific genetic effects influence variation in body composition

(2008) M. C. Zillikens et al.   DIABETOLOGIA

Mapping the Genetic Architecture of Gene Expression in Human Liver

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