Diastereo- and enantioselective [3 + 3] cycloaddition of spirocyclopropyl oxindoles using both aldonitrones and ketonitrones

Catalyst-Controlled Switch in Chemo- and Diastereoselectivities: Annulations of Morita-Baylis-Hillman Carbonates from Isatins

(2016) Gu Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters

(2016) Xing-Ping Zeng et al.   CHEMICAL REVIEWS

Synergistic Catalysis: Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters

(2016) Marta Meazza et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric [3 + 2] Cycloaddition of Vinylcyclopropanes and α,β-Unsaturated Aldehydes by Synergistic Palladium and Organocatalysis

(2016) Kim Søholm Halskov et al.   ORGANIC LETTERS

Cascade Reaction of Donor–Acceptor Cyclopropanes: Mechanistic Studies on Cycloadditions with Nitrosoarenes and cis-Diazenes

(2016) Tristan Chidley et al.   ORGANIC LETTERS

New developments of ketonitrones in organic synthesis

(2016) Wei-Min Shi et al.   Organic Chemistry Frontiers

Catalytic Enantioselective Construction of Quaternary Stereocenters: Assembly of Key Building Blocks for the Synthesis of Biologically Active Molecules

(2015) Yiyang Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Squaramide-Catalyzed Synthesis of Enantioenriched Spirocyclic Oxindoles via Ketimine Intermediates with Multiple Active Sites

(2015) Qiang-Sheng Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dual Catalysis for the Redox Annulation of Nitroalkynes with Indoles: Enantioselective Construction of Indolin-3-ones Bearing Quaternary Stereocenters

(2015) Ren-Rong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Enamine-Activation of Cyclopropanes for Highly Stereoselective Formation of Cyclobutanes

(2015) Kim Søholm Halskov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Annulation of Donor–Acceptor Cyclopropanes with Dienes

(2015) Hao Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbocycles from donor–acceptor cyclopropanes

(2015) Huck K. Grover et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic asymmetric synthesis of polysubstituted spirocyclopropyl oxindoles: organocatalysis versus transition metal catalysis

(2015) Zhong-Yan Cao et al.   Organic Chemistry Frontiers

Discovery and Application of Doubly Quaternized Cinchona-Alkaloid-Based Phase-Transfer Catalysts

(2014) Bangping Xiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of 2,3-Dihydropyrroles by Ring-Opening/Cyclization of Cyclopropyl Ketones Using Primary Amines

(2014) Yong Xia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Triple Relay Catalysis: Enantioselective Synthesis of Spirocyclic Indolines through a One-Pot Process Featuring an Asymmetric 6π Electrocyclization

(2014) Xiao-Ping Yin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Tamura Cycloadditions

(2014) Francesco Manoni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A New Golden Age for Donor-Acceptor Cyclopropanes

(2014) Tobias F. Schneider et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The use of spirocyclic scaffolds in drug discovery

(2014) Yajun Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Four-Membered Ring-Containing Spirocycles: Synthetic Strategies and Opportunities

(2014) Erick M. Carreira et al.   CHEMICAL REVIEWS

Catalytic Asymmetric Formal [3+3] Cycloaddition of an Azomethine Ylide with 3-Indolylmethanol: Enantioselective Construction of a Six-Membered Piperidine Framework

(2014) Feng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Ruthenium-Catalyzed 1,3-Dipolar Cycloadditions between C-Carboalkoxy Ketonitrones and Methacrolein: Solvent Effect on Reaction Selectivity and Its Rational

(2014) Khalid B. Selim et al.   JOURNAL OF ORGANIC CHEMISTRY

Dynamic Kinetic Asymmetric [3 + 2] Annulation Reactions of Aminocyclopropanes

(2014) Florian de Nanteuil et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic enantioselective synthesis of quaternary carbon stereocentres

(2014) Kyle W. Quasdorf et al.   NATURE

Organocatalytic [4+2] addition reactions via tetraenamine intermediate

(2014) Julian Stiller et al.   Chemical Science

Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles

(2013) Liang Hong et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Enantioselective [3+2] Annulation of Cyclic Enol Silyl Ethers with Donor-Acceptor Cyclopropanes: Accessing3a-Hydroxy [n.3.0]Carbobicycles

(2013) Hao Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Highly Enantioselective Cyclopentannulation of Indoles with Donor–Acceptor Cyclopropanes

(2013) Hu Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Stereoselective Olefin Cyclopropanation of Diazooxindoles Catalyzed by a C2-Symmetric Spiroketal Bisphosphine/Au(I) Complex

(2013) Zhong-Yan Cao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diversifying complexity

(2013) Indrajeet Sharma et al.   Nature Chemistry

Urea-catalyzed construction of oxazinanes

(2013) Andrea M. Hardman et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Synthesis of Indole Homo-Michael Adducts via Dynamic Kinetic Friedel–Crafts Alkylation with Cyclopropanes

(2013) Steven M. Wales et al.   ORGANIC LETTERS

Catalytic [4+2] Cyclization of α,β-Unsaturated Acyl Chlorides with 3-Alkylenyloxindoles: Highly Diastereo- and Enantioselective Synthesis of Spirocarbocyclic Oxindoles

(2012) Li-Tao Shen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Diastereo- and Enantioselective Formal [3 + 2]-Cycloadditions of Substituted Vinylcyclopropanes

(2012) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Side-Arm-Promoted Highly Enantioselective Ring-Opening Reactions and Kinetic Resolution of Donor–Acceptor Cyclopropanes with Amines

(2012) You-Yun Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Diastereo- and Enantioselective Synthesis of Substituted Cyclopentanes through a Dynamic Kinetic Asymmetric Formal [3+2]-Cycloaddition of Vinyl Cyclopropanes and Alkylidene Azlactones

(2011) Barry M. Trost et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective methodologies for the synthesis of spiro compounds

(2011) Ramon Rios   CHEMICAL SOCIETY REVIEWS

Polarity Inversion of Donor–Acceptor Cyclopropanes: Disubstituted δ-Lactones via Enantioselective Iridium Catalysis

(2011) Joseph Moran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trienamines in Asymmetric Organocatalysis: Diels−Alder and Tandem Reactions

(2011) Zhi-Jun Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Counteranion Synergistic Organocatalysis under High Temperature: Efficient Construction of Optically Pure Spiro[cyclohexanone-oxindole] Backbone

(2011) Yu-Bao Lan et al.   ORGANIC LETTERS

Recent progress in enantioselective synthesis of C3-functionalized oxindoles: rare earth metals take action

(2011) Ke Shen et al.   Chemical Science

Complexity-Building Annulations of Strained Cycloalkanes and C═O π Bonds

(2010) Matthew J. Campbell et al.   JOURNAL OF ORGANIC CHEMISTRY

Dynamic Kinetic Asymmetric Synthesis of Substituted Pyrrolidines from Racemic Cyclopropanes and Aldimines: Reaction Development and Mechanistic Insights

(2010) Andrew T. Parsons et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

(2010) Andrey P. Antonchick et al.   Nature Chemistry

Targeting Structural and Stereochemical Complexity by Organocascade Catalysis: Construction of Spirocyclic Oxindoles Having Multiple Stereocenters

(2009) Giorgio Bencivenni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Heterocycles from cyclopropanes: applications in natural product synthesis

(2009) Cheryl A. Carson et al.   CHEMICAL SOCIETY REVIEWS

Catalytic Enantioselective Synthesis of Tetrahydrofurans: A Dynamic Kinetic Asymmetric [3 + 2] Cycloaddition of Racemic Cyclopropanes and Aldehydes

(2009) Andrew T. Parsons et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

(2009) Xiao-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of FR901483

(2009) Cheryl A. Carson et al.   ORGANIC LETTERS

Stereodivergent Methodology for the Synthesis of Complex Pyrrolidines

(2008) Stephen K. Jackson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY