From a Library of MAG Antagonists to Nanomolar CD22 Ligands

CD22-Antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold

(2011) Hajjaj H.M. Abdu-Allah et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Lectin inhibition assays for the analysis of bioactive milk sialoglycoconjugates

(2011) Hendrik Koliwer-Brandl et al.   INTERNATIONAL DAIRY JOURNAL

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

In vivo targeting of B-cell lymphoma with glycan ligands of CD22

(2010) W. C. Chen et al.   BLOOD

Kinetic and thermodynamic properties of MAG antagonists

(2010) Stefanie Mesch et al.   CARBOHYDRATE RESEARCH

Lipophilicity in drug discovery

(2010) Michael J Waring   Expert Opinion on Drug Discovery

Low Molecular Weight Antagonists of the Myelin-Associated Glycoprotein: Synthesis, Docking, and Biological Evaluation

(2010) Stefanie Mesch et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phosphorylated Human Lectin Galectin-3: Analysis of Ligand Binding by Histochemical Monitoring of Normal/Malignant Squamous Epithelia and by Isothermal Titration Calorimetry

(2009) P. Szabo et al.   ANATOMIA HISTOLOGIA EMBRYOLOGIA

Potent small molecule mouse CD22-inhibitors: Exploring the interaction of the residue at C-2 of sialic acid scaffold

(2009) Hajjaj H.M. Abdu-Allah et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Lectins as pattern recognition molecules: The effects of epitope density in innate immunity

(2009) T. K Dam et al.   GLYCOBIOLOGY

CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions

(2009) Lars Nitschke   IMMUNOLOGICAL REVIEWS

Examination of the Biological Role of the α(2→6)-Linked Sialic Acid in Gangliosides Binding to the Myelin-Associated Glycoprotein (MAG)

(2009) Oliver Schwardt et al.   JOURNAL OF MEDICINAL CHEMISTRY

Siglecs as targets for therapy in immune-cell-mediated disease

(2009) Mary K. O’Reilly et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A Decade of Rituximab: Improving Survival Outcomes in Non-Hodgkin's Lymphoma

(2008) Arturo Molina   Annual Review of Medicine

Newer monoclonal antibodies for hematological malignancies

(2008) Jorge Castillo et al.   EXPERIMENTAL HEMATOLOGY

Design, Synthesis, and Structure−Affinity Relationships of Novel Series of Sialosides as CD22-Specific Inhibitors

(2008) Hajjaj H. M. Abdu-Allah et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bifunctional CD22 Ligands Use Multimeric Immunoglobulins as Protein Scaffolds in Assembly of Immune Complexes on B Cells

(2008) Mary K. O’Reilly et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY