The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer
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Title
The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer
Authors
Keywords
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Journal
Epigenomics
Volume 9, Issue 6, Pages 919-931
Publisher
Future Medicine Ltd
Online
2017-05-19
DOI
10.2217/epi-2017-0034
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Note: Only part of the references are listed.- Increased Brahma-related Gene 1 Expression Predicts Distant Metastasis and Shorter Survival in Patients with Invasive Ductal Carcinoma of the Breast
- (2016) SUNG-IM DO et al. ANTICANCER RESEARCH
- Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1
- (2016) Ramin Dubey et al. CANCER RESEARCH
- Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies
- (2016) Wen Li et al. DRUG RESISTANCE UPDATES
- Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit
- (2016) Brian S. Gerstenberger et al. JOURNAL OF MEDICINAL CHEMISTRY
- Chromatin Regulators as a Guide for Cancer Treatment Choice
- (2016) Zachary A. Gurard-Levin et al. MOLECULAR CANCER THERAPEUTICS
- Regulation of DNA Translocation Efficiency within the Chromatin Remodeler RSC/Sth1 Potentiates Nucleosome Sliding and Ejection
- (2016) Cedric R. Clapier et al. MOLECULAR CELL
- Genomic analyses identify molecular subtypes of pancreatic cancer
- (2016) Peter Bailey et al. NATURE
- SMARCA4/Brg1 coordinates genetic and epigenetic networks underlying Shh-type medulloblastoma development
- (2016) X Shi et al. ONCOGENE
- BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways
- (2016) L Jubierre et al. ONCOGENE
- Frequent involvement of chromatin remodeler alterations in gastric field cancerization
- (2015) Hideyuki Takeshima et al. CANCER LETTERS
- The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies
- (2015) Bhavatarini Vangamudi et al. CANCER RESEARCH
- Genomic Classification of Cutaneous Melanoma
- (2015) Rehan Akbani et al. CELL
- Microphthalmia-associated transcription factor expression levels in melanoma cells contribute to cell invasion and proliferation
- (2015) Jiri Vachtenheim et al. EXPERIMENTAL DERMATOLOGY
- Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation
- (2015) Nilotpal Roy et al. GENES & DEVELOPMENT
- The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation
- (2015) Qiong Wu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type
- (2015) Anthony N Karnezis et al. JOURNAL OF PATHOLOGY
- Glucocorticoid Receptor Transcriptional Activation via the BRG1-Dependent Recruitment of TOP2β and Ku70/86
- (2015) Kevin W. Trotter et al. MOLECULAR AND CELLULAR BIOLOGY
- Brg-1 targeting of novel miR550a-5p/RNF43/Wnt signaling axis regulates colorectal cancer metastasis
- (2015) G Wang et al. ONCOGENE
- Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy
- (2015) Claudia Wellbrock et al. Pigment Cell & Melanoma Research
- Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells
- (2015) Patrick Laurette et al. eLife
- Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance
- (2015) O. Fedorov et al. Science Advances
- Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics
- (2015) C. Kadoch et al. Science Advances
- SWI/SNF complexes are required for full activation of the DNA-damage response
- (2015) Stephanie L. Smith-Roe et al. Oncotarget
- SWI/SNF chromatin remodeling complexes and cancer
- (2014) Jaclyn A. Biegel et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS
- Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance
- (2014) M. Buscarlet et al. BLOOD
- SWI/SNF Chromatin Remodeling Enzymes in Melanocyte Differentiation and Melanoma
- (2014) A. Mehrotra et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- BRG1 promotes chemoresistance of pancreatic cancer cells through crosstalking with Akt signalling
- (2014) Xiaoran Liu et al. EUROPEAN JOURNAL OF CANCER
- Wnt3a expression is associated with epithelial-mesenchymal transition and promotes colon cancer progression
- (2014) Lisha Qi et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Residual Complexes Containing SMARCA2 (BRM) Underlie the Oncogenic Drive of SMARCA4 (BRG1) Mutation
- (2014) B. G. Wilson et al. MOLECULAR AND CELLULAR BIOLOGY
- Targeting BRG1 Chromatin Remodeler via Its Bromodomain for Enhanced Tumor Cell Radiosensitivity In Vitro and In Vivo
- (2014) S.-J. Kwon et al. MOLECULAR CANCER THERAPEUTICS
- The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma
- (2014) Guido von Figura et al. NATURE CELL BIOLOGY
- KRAS: feeding pancreatic cancer proliferation
- (2014) Kirsten L. Bryant et al. TRENDS IN BIOCHEMICAL SCIENCES
- A rationale to target the SWI/SNF complex for cancer therapy
- (2014) Anja F. Hohmann et al. TRENDS IN GENETICS
- Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine
- (2014) Aliaksei Z. Holik et al. PLoS Genetics
- A Synthetic Lethality-Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1
- (2013) T. Oike et al. CANCER RESEARCH
- Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
- (2013) J. Shi et al. GENES & DEVELOPMENT
- Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
- (2013) Cigall Kadoch et al. NATURE GENETICS
- Nucleosome sliding mechanisms: new twists in a looped history
- (2013) Felix Mueller-Planitz et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseases
- (2013) O A Romero et al. ONCOGENE
- BRG1 promotes survival of UV-irradiated melanoma cells by cooperating with MITF to activate the melanoma inhibitor of apoptosis gene
- (2013) Srinivas V. Saladi et al. Pigment Cell & Melanoma Research
- MITF-Independent Pro-Survival Role of BRG1-Containing SWI/SNF Complex in Melanoma Cells
- (2013) Lubica Ondrušová et al. PLoS One
- BRG1 Is a Prognostic Marker and Potential Therapeutic Target in Human Breast Cancer
- (2013) Jin Bai et al. PLoS One
- The Spectrum of SWI/SNF Mutations, Ubiquitous in Human Cancers
- (2013) A. Hunter Shain et al. PLoS One
- MAX Inactivation in Small Cell Lung Cancer Disrupts MYC-SWI/SNF Programs and Is Synthetic Lethal with BRG1
- (2013) O. A. Romero et al. Cancer Discovery
- Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma
- (2012) Janel L. Kopp et al. CANCER CELL
- Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features
- (2012) Daisuke Matsubara et al. CANCER SCIENCE
- Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity
- (2012) Anbarasi Kothandapani et al. EXPERIMENTAL CELL RESEARCH
- BRG1 expression is increased in human glioma and controls glioma cell proliferation, migration and invasion in vitro
- (2012) Jin Bai et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- The SnAC Domain of SWI/SNF Is a Histone Anchor Required for Remodeling
- (2012) P. Sen et al. MOLECULAR AND CELLULAR BIOLOGY
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- The BRG1 Chromatin Remodeler Protects Against Ovarian Cysts, Uterine Tumors, and Mammary Tumors in a Lineage-Specific Manner
- (2012) Daniel W. Serber et al. PLoS One
- Global Epigenetic Changes Induced by SWI2/SNF2 Inhibitors Characterize Neomycin-Resistant Mammalian Cells
- (2012) Popy Dutta et al. PLoS One
- Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer
- (2012) A. H. Shain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diverse functions of ATP-dependent chromatin remodeling complexes in development and cancer
- (2011) Jiang I. Wu ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Diversity of operation in ATP-dependent chromatin remodelers
- (2011) Swetansu K. Hota et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreas
- (2011) Marco Dal Molin et al. HUMAN PATHOLOGY
- A new, highly conserved domain in Swi2/Snf2 is required for SWI/SNF remodeling
- (2011) Payel Sen et al. NUCLEIC ACIDS RESEARCH
- SWI/SNF chromatin remodeling complex is critical for the expression of microphthalmia-associated transcription factor in melanoma cells
- (2010) Jiri Vachtenheim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cells
- (2010) T Watanabe et al. BRITISH JOURNAL OF CANCER
- BRG1 expression is increased in human cutaneous melanoma
- (2010) H. Lin et al. BRITISH JOURNAL OF DERMATOLOGY
- Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells
- (2010) A. Vazquez-Martin et al. CELL PROLIFERATION
- Mechanism(s) of SWI/SNF-Induced Nucleosome Mobilization
- (2010) Ning Liu et al. CHEMBIOCHEM
- Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness
- (2010) Srinivas Saladi et al. Molecular Cancer
- Chromatin remodelling during development
- (2010) Lena Ho et al. NATURE
- Understanding the Words of Chromatin Regulation
- (2009) Jiang I. Wu et al. CELL
- Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma
- (2009) B Keenen et al. ONCOGENE
- The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells
- (2009) S R Naidu et al. ONCOGENE
- The SWI/SNF complex and cancer
- (2009) D Reisman et al. ONCOGENE
- Mammalian SWI/SNF chromatin remodeling complexes are required to prevent apoptosis after DNA damage
- (2008) Ji-Hye Park et al. DNA REPAIR
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