Diverse functions of ATP-dependent chromatin remodeling complexes in development and cancer

Identification and characterization of novel potentially oncogenic mutations in the human BAF57 gene in a breast cancer patient

(2011) M. Ángeles Villaronga et al.   BREAST CANCER RESEARCH AND TREATMENT

Chromatin Connections to Pluripotency and Cellular Reprogramming

(2011) Stuart H. Orkin et al.   CELL

Control of the Embryonic Stem Cell State

(2011) Richard A. Young   CELL

ATP-dependent chromatin remodeling: genetics, genomics and mechanisms

(2011) Diana C Hargreaves et al.   CELL RESEARCH

Chromatin Remodeling in Cardiovascular Development and Physiology

(2011) Pei Han et al.   CIRCULATION RESEARCH

Smarcd3b and Gata5 promote a cardiac progenitor fate in the zebrafish embryo

(2011) X. Lou et al.   DEVELOPMENT

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

(2011) Ignacio Varela et al.   NATURE

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function

(2011) Lena Ho et al.   NATURE CELL BIOLOGY

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

(2011) Yaoting Gui et al.   NATURE GENETICS

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

(2011) Meng Li et al.   NATURE GENETICS

Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development

(2011) X. Zhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels

(2011) C. T. Griffin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin remodelling complex dosage modulates transcription factor function in heart development

(2011) Jun K. Takeuchi et al.   Nature Communications

Germline Nonsense Mutation and Somatic Inactivation of SMARCA4/BRG1 in a Family with Rhabdoid Tumor Predisposition Syndrome

(2010) Reinhard Schneppenheim et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Chromatin Regulatory Mechanisms in Pluripotency

(2010) Julie A. Lessard et al.   Annual Review of Cell and Developmental Biology

A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations

(2010) J. Krosl et al.   BLOOD

Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cells

(2010) T Watanabe et al.   BRITISH JOURNAL OF CANCER

BRG1 expression is increased in human cutaneous melanoma

(2010) H. Lin et al.   BRITISH JOURNAL OF DERMATOLOGY

Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncogenic Transformation

(2010) Boris G. Wilson et al.   CANCER CELL

Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming

(2010) Nishant Singhal et al.   CELL

Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues

(2010) Jacob H. Hanna et al.   CELL

Recipient cell nuclear factors are required for reprogramming by nuclear transfer

(2010) D. Egli et al.   DEVELOPMENT

Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors

(2010) Salvador Rodriguez-Nieto et al.   HUMAN MUTATION

Chromatin regulation by Brg1 underlies heart muscle development and disease

(2010) Calvin T. Hang et al.   NATURE

Nuclear reprogramming to a pluripotent state by three approaches

(2010) Shinya Yamanaka et al.   NATURE

Epigenetic modifications in pluripotent and differentiated cells

(2010) Alexander Meissner   NATURE BIOTECHNOLOGY

BRD7 is a candidate tumour suppressor gene required for p53 function

(2010) Jarno Drost et al.   NATURE CELL BIOLOGY

Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway

(2010) Zainab Jagani et al.   NATURE MEDICINE

Epigenetic control of neural precursor cell fate during development

(2010) Yusuke Hirabayashi et al.   NATURE REVIEWS NEUROSCIENCE

ARID1AMutations in Endometriosis-Associated Ovarian Carcinomas

(2010) Kimberly C. Wiegand et al.   NEW ENGLAND JOURNAL OF MEDICINE

Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21WAF1/CIP1 expression

(2010) J Ahn et al.   ONCOGENE

Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence

(2010) A. E. Burrows et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

(2010) Siân Jones et al.   SCIENCE

The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer

(2010) Monique T. Barakat et al.   TRENDS IN MOLECULAR MEDICINE

Oncogenesis Caused by Loss of the SNF5 Tumor Suppressor Is Dependent on Activity of BRG1, the ATPase of the SWI/SNF Chromatin Remodeling Complex

(2009) X. Wang et al.   CANCER RESEARCH

Understanding the Words of Chromatin Regulation

(2009) Jiang I. Wu et al.   CELL

Genomic Analysis Using High-Density Single Nucleotide Polymorphism-Based Oligonucleotide Arrays and Multiplex Ligation-Dependent Probe Amplification Provides a Comprehensive Analysis of INI1/SMARCB1 in Malignant Rhabdoid Tumors

(2009) E. M. Jackson et al.   CLINICAL CANCER RESEARCH

ATP-dependent chromatin remodeling in neural development

(2009) Andrew S Yoo et al.   CURRENT OPINION IN NEUROBIOLOGY

Molecular basis of CD4 repression by the Swi/Snf-like BAF chromatin remodeling complex

(2009) Mimi Wan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The early heart remodelled

(2009) Fu-Sen Liang et al.   NATURE

MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

(2009) Andrew S. Yoo et al.   NATURE

Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors

(2009) Jun K. Takeuchi et al.   NATURE

Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes

(2009) Ashby J Morrison et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells

(2009) S R Naidu et al.   ONCOGENE

An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network

(2009) L. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency

(2009) L. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smarcc1/Baf155 Couples Self-Renewal Gene Repression with Changes in Chromatin Structure in Mouse Embryonic Stem Cells

(2009) Christoph Schaniel et al.   STEM CELLS

Interaction of HP1 and Brg1/Brm with the Globular Domain of Histone H3 Is Required for HP1-Mediated Repression

(2009) Marc Lavigne et al.   PLoS Genetics

BAF180 Is a Critical Regulator of p21 Induction and a Tumor Suppressor Mutated in Breast Cancer

(2008) W. Xia et al.   CANCER RESEARCH

Targeted Knockout of BRG1 Potentiates Lung Cancer Development

(2008) S. Glaros et al.   CANCER RESEARCH

Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming

(2008) Rudolf Jaenisch et al.   CELL

An RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Identity

(2008) Thomas G. Fazzio et al.   CELL

Coronary development is regulated by ATP-dependent SWI/SNF chromatin remodeling component BAF180

(2008) Xuling Huang et al.   DEVELOPMENTAL BIOLOGY

Endocardial Brg1 Represses ADAMTS1 to Maintain the Microenvironment for Myocardial Morphogenesis

(2008) Kryn Stankunas et al.   DEVELOPMENTAL CELL

Hedgehog Signaling in Development and Cancer

(2008) Jin Jiang et al.   DEVELOPMENTAL CELL

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex

(2008) M. Lange et al.   GENES & DEVELOPMENT

Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines

(2008) Pedro P. Medina et al.   HUMAN MUTATION

BAF60a Interacts with p53 to Recruit the SWI/SNF Complex

(2008) Jaehak Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel genetic strategy reveals unexpected roles of the Swi–Snf–like chromatin-remodeling BAF complex in thymocyte development

(2008) Anant Jani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The genetics of early telencephalon patterning: some assembly required

(2008) Jean M. Hébert et al.   NATURE REVIEWS NEUROSCIENCE

The HSA domain binds nuclear actin-related proteins to regulate chromatin-remodeling ATPases

(2008) Heather Szerlong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Calcium-Dependent Switch in a CREST-BRG1 Complex Regulates Activity-Dependent Gene Expression

(2008) Zilong Qiu et al.   NEURON

Decoding the Epigenetic Language of Neuronal Plasticity

(2008) Emiliana Borrelli et al.   NEURON

Small cell undifferentiated variant of hepatoblastoma: Adverse clinical and molecular features similar to rhabdoid tumors

(2008) Angela D. Trobaugh-Lotrario et al.   PEDIATRIC BLOOD & CANCER

ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a

(2008) X. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BAF250B-Associated SWI/SNF Chromatin-Remodeling Complex Is Required to Maintain Undifferentiated Mouse Embryonic Stem Cells

(2008) Zhijiang Yan et al.   STEM CELLS

SWI/SNF-Brg1 Regulates Self-Renewal and Occupies Core Pluripotency-Related Genes in Embryonic Stem Cells

(2008) Benjamin L. Kidder et al.   STEM CELLS

The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development

(2007) C. T. Griffin et al.   DEVELOPMENT