Epigenetic regulation of noncoding RNA transcription by mammalian RNA polymerase III

Induction of proto-oncogene BRF2 in breast cancer cells by the dietary soybean isoflavone daidzein

(2015) Jana Koo et al.   BMC CANCER

Emerging Roles for Maf1 beyond the Regulation of RNA Polymerase III Activity

(2015) Akshat Khanna et al.   JOURNAL OF MOLECULAR BIOLOGY

Involvement of RNA Polymerase III in Immune Responses

(2015) Damian Graczyk et al.   MOLECULAR AND CELLULAR BIOLOGY

PRC2 regulates RNA polymerase III transcribed non-translated RNA gene transcription through EZH2 and SUZ12 interaction with TFIIIC complex

(2015) Chang Liu et al.   NUCLEIC ACIDS RESEARCH

Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells

(2015) Sarina Ravens et al.   Epigenetics & Chromatin

SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation

(2015) Dhaval Varshney et al.   Nature Communications

Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III

(2015) Isabelle Thiffault et al.   Nature Communications

Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment

(2015) Matt J Silver et al.   GENOME BIOLOGY

Epigenetic silencing of the non-coding RNA nc886 provokes oncogenes during human esophageal tumorigenesis

(2015) Hyun-Sung Lee et al.   Oncotarget

nc886, a non-coding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer

(2015) Kwang-Soo Lee et al.   Oncotarget

Human CLP1 Mutations Alter tRNA Biogenesis, Affecting Both Peripheral and Central Nervous System Function

(2014) Ender Karaca et al.   CELL

CLP1 Founder Mutation Links tRNA Splicing and Maturation to Cerebellar Development and Neurodegeneration

(2014) Ashleigh E. Schaffer et al.   CELL

Variable maternal methylation overlapping thenc886/vtRNA2-1locus is locked between hypermethylated repeats and is frequently altered in cancer

(2014) Valeria Romanelli et al.   Epigenetics

RNA Polymerase III Transcriptomes in Human Embryonic Stem Cells and Induced Pluripotent Stem Cells, and Relationships with Pluripotency Transcription Factors

(2014) Ravi K. Alla et al.   PLoS One

TFIIB-Related Factor 2 Over Expression Is a Prognosis Marker for Early-Stage Non-Small Cell Lung Cancer Correlated with Tumor Angiogenesis

(2014) Ming Lu et al.   PLoS One

Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration

(2014) R. Ishimura et al.   SCIENCE

Epigenetic regulation of transcription by RNA polymerase III

(2013) Purnima Bhargava   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A unique nucleosome arrangement, maintained actively by chromatin remodelers facilitates transcription of yeast tRNA genes

(2013) Yatendra Kumar et al.   BMC GENOMICS

DNA Methylation-Mediated Repression of miR-886-3p Predicts Poor Outcome of Human Small Cell Lung Cancer

(2013) J. Cao et al.   CANCER RESEARCH

Role of phosphorylated histone H3 serine 10 in DEN-induced deregulation of Pol III genes and cell proliferation and transformation

(2013) Qian Zhong et al.   CARCINOGENESIS

Overexpression of TFIIB-related factor 2 is significantly correlated with tumor angiogenesis and poor survival in patients with esophageal squamous cell cancer

(2013) Ming Lu et al.   MEDICAL ONCOLOGY

CLP1 links tRNA metabolism to progressive motor-neuron loss

(2013) Toshikatsu Hanada et al.   NATURE

Linkage Study and Exome Sequencing Identify a BDP1 Mutation Associated with Hereditary Hearing Loss

(2013) Giorgia Girotto et al.   PLoS One

ERα mediates alcohol-induced deregulation of Pol III genes in breast cancer cells

(2012) Qingsong Zhang et al.   CARCINOGENESIS

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Histone phosphorylation

(2012) Dorine Rossetto et al.   Epigenetics

A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver

(2012) D. Canella et al.   GENOME RESEARCH

Signals from noncoding RNAs: Unconventional roles for conventional pol III transcripts

(2012) Shanshan Hu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation of Human RNA Polymerase III Transcription by DNMT1 and DNMT3a DNA Methyltransferases

(2012) Tharakeswari Selvakumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations of POLR3A Encoding a Catalytic Subunit of RNA Polymerase Pol III Cause a Recessive Hypomyelinating Leukodystrophy

(2011) Geneviève Bernard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in POLR3A and POLR3B Encoding RNA Polymerase III Subunits Cause an Autosomal-Recessive Hypomyelinating Leukoencephalopathy

(2011) Hirotomo Saitsu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Recessive Mutations in POLR3B, Encoding the Second Largest Subunit of Pol III, Cause a Rare Hypomyelinating Leukodystrophy

(2011) Martine Tétreault et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

(2011) M. B. Treppendahl et al.   BLOOD

RNA polymerase III transcription in cancer: the BRF2 connection

(2011) Stephanie Cabarcas et al.   Molecular Cancer

Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells

(2011) Lucie Carrière et al.   NUCLEIC ACIDS RESEARCH

Phosphorylation of histone H3 serine 28 modulates RNA polymerase III-dependent transcription

(2011) Q Zhang et al.   ONCOGENE

Classification, diagnosis and potential mechanisms in Pontocerebellar Hypoplasia

(2011) Yasmin Namavar et al.   Orphanet Journal of Rare Diseases

Precursor miR-886, a novel noncoding RNA repressed in cancer, associates with PKR and modulates its activity

(2011) K. Lee et al.   RNA

Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation

(2010) Till Bartke et al.   CELL

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

(2010) Qihuang Jin et al.   EMBO JOURNAL

Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells

(2010) D. Canella et al.   GENOME RESEARCH

Insulators and promoters: closer than we think

(2010) Jesse R. Raab et al.   NATURE REVIEWS GENETICS

Pol II and its associated epigenetic marks are present at Pol III–transcribed noncoding RNA genes

(2010) Artem Barski et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors

(2010) Andrew J Oler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genomic binding profiles of functionally distinct RNA polymerase III transcription complexes in human cells

(2010) Zarmik Moqtaderi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs

(2009) Helena Persson et al.   NATURE CELL BIOLOGY

tRNA over-expression in breast cancer and functional consequences

(2009) Mariana Pavon-Eternod et al.   NUCLEIC ACIDS RESEARCH

Structure of Eukaryotic RNA Polymerases

(2008) P. Cramer et al.   Annual Review of Biophysics

Noncoding human Y RNAs are overexpressed in tumours and required for cell proliferation

(2008) C P Christov et al.   BRITISH JOURNAL OF CANCER

CpG-methylation silences the activity of the RNA polymerase III transcribed EBER-1 promoter of Epstein-Barr virus

(2008) Ferenc Banati et al.   FEBS LETTERS

Chromatin Structure and Expression of a Gene Transcribed by RNA Polymerase III Are Independent of H2A.Z Deposition

(2008) A. G. Arimbasseri et al.   MOLECULAR AND CELLULAR BIOLOGY

Different Functional Modes of p300 in Activation of RNA Polymerase III Transcription from Chromatin Templates

(2008) C. Mertens et al.   MOLECULAR AND CELLULAR BIOLOGY

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS