PRC2 regulates RNA polymerase III transcribed non-translated RNA gene transcription through EZH2 and SUZ12 interaction with TFIIIC complex

PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression

(2015) Junhu Wan et al.   NUCLEIC ACIDS RESEARCH

Interactions between JARID2 and Noncoding RNAs Regulate PRC2 Recruitment to Chromatin

(2014) Syuzo Kaneko et al.   MOLECULAR CELL

Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells

(2013) Eunhee Kim et al.   CANCER CELL

Role of phosphorylated histone H3 serine 10 in DEN-induced deregulation of Pol III genes and cell proliferation and transformation

(2013) Qian Zhong et al.   CARCINOGENESIS

A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma

(2013) Meena Kanduri et al.   Epigenetics

Global Levels of H3K27me3 Track with Differentiation in Vivo and Are Deregulated by MYC in Prostate Cancer

(2012) Laxmi G. Pellakuru et al.   AMERICAN JOURNAL OF PATHOLOGY

PRC2 directly methylates GATA4 and represses its transcriptional activity

(2012) A. He et al.   GENES & DEVELOPMENT

Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis

(2012) Sandy Leung-Kuen Au et al.   HEPATOLOGY

Direct Regulation of tRNA and 5S rRNA Gene Transcription by Polo-like Kinase 1

(2012) Jennifer A. Fairley et al.   MOLECULAR CELL

EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent

(2012) K. Xu et al.   SCIENCE

FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells

(2011) Juan Du et al.   BREAST CANCER RESEARCH AND TREATMENT

ALDH1A1 Is a Novel EZH2 Target Gene in Epithelial Ovarian Cancer Identified by Genome-Wide Approaches

(2011) H. Li et al.   Cancer Prevention Research

Corepressor Protein CDYL Functions as a Molecular Bridge between Polycomb Repressor Complex 2 and Repressive Chromatin Mark Trimethylated Histone Lysine 27

(2011) Yu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased expression of EZH2 is associated with upregulation of ER and favorable outcome to tamoxifen in advanced breast cancer

(2010) E. A. Reijm et al.   BREAST CANCER RESEARCH AND TREATMENT

Pol II and its associated epigenetic marks are present at Pol III–transcribed noncoding RNA genes

(2010) Artem Barski et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors

(2010) Andrew J Oler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genomic binding profiles of functionally distinct RNA polymerase III transcription complexes in human cells

(2010) Zarmik Moqtaderi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1

(2010) T. Kantidakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jarid2/Jumonji Coordinates Control of PRC2 Enzymatic Activity and Target Gene Occupancy in Pluripotent Cells

(2009) Jamy C. Peng et al.   CELL

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

(2008) Satoshi Fujii et al.   CANCER SCIENCE

RETRACTED: Elevated tRNAiMet Synthesis Can Drive Cell Proliferation and Oncogenic Transformation

(2008) Lynne Marshall et al.   CELL

Enhancer of Zeste Homologue 2 (EZH2) Down-regulates RUNX3 by Increasing Histone H3 Methylation

(2008) Satoshi Fujii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTEN Represses RNA Polymerase III-Dependent Transcription by Targeting the TFIIIB Complex

(2008) A. Woiwode et al.   MOLECULAR AND CELLULAR BIOLOGY

Ezh2 Requires PHF1 To Efficiently Catalyze H3 Lysine 27 Trimethylation In Vivo

(2008) K. Sarma et al.   MOLECULAR AND CELLULAR BIOLOGY