Flightless-I governs cell fate by recruiting the SUMO isopeptidase SENP3 to distinct HOX genes

Structural basis for activity regulation of MLL family methyltransferases

(2016) Yanjing Li et al.   NATURE

Epigenetic balance of gene expression by Polycomb and COMPASS families

(2016) Andrea Piunti et al.   SCIENCE

SUMO Signaling by Hypoxic Inactivation of SUMO-Specific Isopeptidases

(2016) Kathrin Kunz et al.   Cell Reports

A protein kinase A (PKA)/β-catenin pathway sustains the BMP2/DLX3-induced osteogenic differentiation in dental follicle cells (DFCs)

(2015) S. Viale-Bouroncle et al.   CELLULAR SIGNALLING

Trithorax and Polycomb group-dependent regulation: a tale of opposing activities

(2015) S. J. Geisler et al.   DEVELOPMENT

Estrogen Receptor α Regulates Dlx3-Mediated Osteoblast Differentiation

(2015)   MOLECULES AND CELLS

Flightless I (Drosophila) homolog facilitates chromatin accessibility of the estrogen receptor α target genes in MCF-7 breast cancer cells

(2014) Kwang Won Jeong   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant

(2014) S. Denissov et al.   DEVELOPMENT

SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development

(2014) L. Wang et al.   EMBO REPORTS

mTOR Signaling Regulates Nucleolar Targeting of the SUMO-Specific Isopeptidase SENP3

(2014) N. Raman et al.   MOLECULAR AND CELLULAR BIOLOGY

The SUMO-Specific Isopeptidase SENP3 Regulates MLL1/MLL2 Methyltransferase Complexes and Controls Osteogenic Differentiation

(2014) Arnab Nayak et al.   MOLECULAR CELL

What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory

(2014) Philipp A. Steffen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A SET-domain-independent role of WRAD complex in cell-cycle regulatory function of mixed lineage leukemia

(2014) Aamir Ali et al.   NUCLEIC ACIDS RESEARCH

Hox gene regulation and timing in embryogenesis

(2014) Thomas Montavon et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

The SUMO system: a master organizer of nuclear protein assemblies

(2013) Nithya Raman et al.   CHROMOSOMA

SUMO: A Multifaceted Modifier of Chromatin Structure and Function

(2013) Caelin Cubeñas-Potts et al.   DEVELOPMENTAL CELL

The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells

(2013) Deqing Hu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transcriptional regulation by Polycomb group proteins

(2013) Luciano Di Croce et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chromatin organization and global regulation of Hox gene clusters

(2013) T. Montavon et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal Development

(2013) K. Miyamoto et al.   SCIENCE

The Dlx genes as clues to vertebrate genomics and craniofacial evolution

(2013) Masaki Takechi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

WRAD: enabler of the SET1-family of H3K4 methyltransferases

(2012) P. Ernst et al.   Briefings in Functional Genomics

In vivoimpact of Dlx3 conditional inactivation in neural crest-derived craniofacial bones

(2012) Olivier Duverger et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Five Friends of Methylated Chromatin Target of Protein-Arginine-Methyltransferase[Prmt]-1 (Chtop), a Complex Linking Arginine Methylation to Desumoylation

(2012) Pavlos Fanis et al.   MOLECULAR & CELLULAR PROTEOMICS

MLL Histone Methylases Regulate Expression of HDLR-SR-B1 in Presence of Estrogen and Control Plasma Cholesterolin Vivo

(2012) Khairul I. Ansari et al.   MOLECULAR ENDOCRINOLOGY

Function and regulation of SUMO proteases

(2012) Christopher M. Hickey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone Methylases MLL1 and MLL3 Coordinate with Estrogen Receptors in Estrogen-Mediated HOXB9 Expression

(2011) Khairul I. Ansari et al.   BIOCHEMISTRY

The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex

(2011) Elisabeth Finkbeiner et al.   EMBO JOURNAL

Regulation of Focal Adhesions by Flightless I Involves Inhibition of Paxillin Phosphorylation via a Rac1-Dependent Pathway

(2011) Zlatko Kopecki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

HOXC6 Is Transcriptionally Regulated via Coordination of MLL Histone Methylase and Estrogen Receptor in an Estrogen Environment

(2011) Khairul I. Ansari et al.   JOURNAL OF MOLECULAR BIOLOGY

Decreased expression of Flightless I, a gelsolin family member and developmental regulator, in early-gestation fetal wounds improves healing

(2011) Cheng-Hung Lin et al.   MAMMALIAN GENOME

Coronin 2A mediates actin-dependent de-repression of inflammatory response genes

(2011) Wendy Huang et al.   NATURE

The Transcription Factor DLX3 Regulates the Osteogenic Differentiation of Human Dental Follicle Precursor Cells

(2011) Sandra Viale-Bouroncle et al.   STEM CELLS AND DEVELOPMENT

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An Ash2L/RbBP5 Heterodimer Stimulates the MLL1 Methyltransferase Activity through Coordinated Substrate Interactions with the MLL1 SET Domain

(2010) Fang Cao et al.   PLoS One

The Differentiation and Gene Expression Profile of Human Dental Follicle Cells

(2010) Michael Saugspier et al.   STEM CELLS AND DEVELOPMENT

SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation

(2009) Chao Huang et al.   EMBO JOURNAL

Mixed lineage leukemia histone methylases play critical roles in estrogen-mediated regulation of HOXC13

(2009) Khairul I. Ansari et al.   FEBS Journal

Recruitment of the SWI/SNF Chromatin Remodeling Complex to Steroid Hormone-regulated Promoters by Nuclear Receptor Coactivator Flightless-I

(2009) Kwang Won Jeong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II

(2009) P. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

(2008) Ali Shilatifard   CURRENT OPINION IN CELL BIOLOGY

Expression and function of Dlx genes in the osteoblast lineage

(2008) Haitao Li et al.   DEVELOPMENTAL BIOLOGY

The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing

(2008) Markus Haindl et al.   EMBO REPORTS

Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases

(2008) Chawon Yun et al.   JOURNAL OF CELL BIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

STRING 8--a global view on proteins and their functional interactions in 630 organisms

(2008) L. J. Jensen et al.   NUCLEIC ACIDS RESEARCH

Flightless I: An actin-remodelling protein and an important negative regulator of wound repair

(2007) Z. Kopecki et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY