Site-specific regulation of histone H1 phosphorylation in pluripotent cell differentiation

Interphase H1 phosphorylation: Regulation and functions in chromatin

(2016) Ruiqi Liao et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The role of linker histone H1 modifications in the regulation of gene expression and chromatin dynamics

(2016) Annalisa Izzo et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Interplay between histone H1 structure and function

(2016) Alicia Roque et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells

(2016) Michelle Gonzales-Cope et al.   BMC GENOMICS

Transcription elongation control by the 7SK snRNP complex: Releasing the pause

(2016) Ryan P. McNamara et al.   CELL CYCLE

Germ Cell Nuclear Factor (GCNF) Represses Oct4 Expression and Globally Modulates Gene Expression in Human Embryonic Stem (hES) Cells

(2016) Hongran Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb

(2016) Alexandre J. C. Quaresma et al.   NUCLEIC ACIDS RESEARCH

A Novel CDK9 Inhibitor Shows Potent Antitumor Efficacy in Preclinical Hematologic Tumor Models

(2014) T. Yin et al.   MOLECULAR CANCER THERAPEUTICS

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

(2014) Nicholas Kwiatkowski et al.   NATURE

RNA helicase DDX21 coordinates transcription and ribosomal RNA processing

(2014) Eliezer Calo et al.   NATURE

Control of Embryonic Stem Cell Identity by BRD4-Dependent Transcriptional Elongation of Super-Enhancer-Associated Pluripotency Genes

(2014) Raffaella Di Micco et al.   Cell Reports

Cyclin-dependent kinases

(2014) Marcos Malumbres   GENOME BIOLOGY

Cyclin-Dependent Kinase Modulators and Cancer Therapy

(2013) Marialucia Gallorini et al.   BIODRUGS

Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor

(2013) T K Albert et al.   BRITISH JOURNAL OF PHARMACOLOGY

SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase

(2013) Xiong Ji et al.   CELL

H1 histones: current perspectives and challenges

(2013) S. W. Harshman et al.   NUCLEIC ACIDS RESEARCH

Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II

(2012) Stéphane Larochelle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamic Distribution of Linker Histone H1.5 in Cellular Differentiation

(2012) Jing-Yu Li et al.   PLoS Genetics

Histone H1 Depletion Impairs Embryonic Stem Cell Differentiation

(2012) Yunzhe Zhang et al.   PLoS Genetics

Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor

(2011) Hiroyuki Hirai et al.   BIOCHEMICAL JOURNAL

Histone H1 Variants Are Differentially Expressed and Incorporated into Chromatin during Differentiation and Reprogramming to Pluripotency

(2011) Jean-Michel Terme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Kinase A-mediated Serine 35 Phosphorylation Dissociates Histone H1.4 from Mitotic Chromosome

(2011) Chi-Shuen Chu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isoform-specific phosphorylation of human linker histone H1.4 in mitosis by the kinase Aurora B

(2011) S. P. Hergeth et al.   JOURNAL OF CELL SCIENCE

Phosphorylation of histone H1 by P-TEFb is a necessary step in skeletal muscle differentiation

(2011) Siobhan K. O'Brien et al.   JOURNAL OF CELLULAR PHYSIOLOGY

XPB, a subunit of TFIIH, is a target of the natural product triptolide

(2011) Denis V Titov et al.   Nature Chemical Biology

Histone H1 interphase phosphorylation becomes largely established in G1 or early S phase and differs in G1 between T-lymphoblastoid cells and normal T cells

(2011) Anna Gréen et al.   Epigenetics & Chromatin

Distinct Epigenomic Landscapes of Pluripotent and Lineage-Committed Human Cells

(2010) R. David Hawkins et al.   Cell Stem Cell

P-TEFb Kinase Complex Phosphorylates Histone H1 to Regulate Expression of Cellular and HIV-1 Genes

(2010) Siobhan K. O'Brien et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone H1 phosphorylation is associated with transcription by RNA polymerases I and II

(2010) Yupeng Zheng et al.   JOURNAL OF CELL BIOLOGY

Retinoids regulate stem cell differentiation

(2010) Lorraine J. Gudas et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Open chromatin in pluripotency and reprogramming

(2010) Alexandre Gaspar-Maia et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Site-specifically phosphorylated forms of H1.5 and H1.2 localized at distinct regions of the nucleus are related to different processes during the cell cycle

(2009) Heribert Talasz et al.   CHROMOSOMA

Post-translational modifications of the linker histone variants and their association with cell mechanisms

(2009) Christopher Wood et al.   FEBS Journal

Genome-wide reduction in H3K9 acetylation during human embryonic stem cell differentiation

(2009) Jana Krejčí et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TFIIH-Associated Cdk7 Kinase Functions in Phosphorylation of C-Terminal Domain Ser7 Residues, Promoter-Proximal Pausing, and Termination by RNA Polymerase II

(2009) K. Glover-Cutter et al.   MOLECULAR AND CELLULAR BIOLOGY

A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

(2009) Hitoshi Niwa et al.   NATURE

Global Transcription in Pluripotent Embryonic Stem Cells

(2008) Sol Efroni et al.   Cell Stem Cell

Histone H1 and its isoforms: Contribution to chromatin structure and function

(2008) Nicole Happel et al.   GENE

M Phase-Specific Phosphorylation of Histone H1.5 at Threonine 10 by GSK-3

(2008) Nicole Happel et al.   JOURNAL OF MOLECULAR BIOLOGY

Global Changes in and Characterization of Specific Sites of Phosphorylation in Mouse and Human Histone H1 Isoforms upon CDK Inhibitor Treatment Using Mass Spectrometry

(2008) Leesa J. Deterding et al.   JOURNAL OF PROTEOME RESEARCH

Cyclin-dependent kinase 9: a key transcriptional regulator and potential drug target in oncology, virology and cardiology

(2008) S WANG et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Depletion of Human Histone H1 Variants Uncovers Specific Roles in Gene Expression and Cell Growth

(2008) Mónica Sancho et al.   PLoS Genetics