MUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner

Chemoradiotherapy followed by consolidation chemotherapy involving paclitaxel and carboplatin and in FIGO stage IIIB/IVA cervical cancer patients

(2017) Seiji Mabuchi et al.   Journal of Gynecologic Oncology

Chemotherapy and molecular targeting therapy for recurrent cervical cancer

(2016) Naotake Tsuda et al.   Chinese Journal of Cancer Research

MUC1 stimulates EGFR expression and function in endometrial cancer

(2016) Brian J. Engel et al.   Oncotarget

Up-regulation of CX3CL1 via Nuclear Factor-κB–dependent Histone Acetylation Is Involved in Paclitaxel-induced Peripheral Neuropathy

(2015) Dai Li et al.   ANESTHESIOLOGY

LRIG1, human EGFR inhibitor, reverses multidrug resistance through modulation of ABCB1 and ABCG2

(2015) Baohui Liu et al.   BRAIN RESEARCH

The modulation of ABC transporter-mediated multidrug resistance in cancer: A review of the past decade

(2015) Rishil J. Kathawala et al.   DRUG RESISTANCE UPDATES

Blocking IL1  Pathway Following Paclitaxel Chemotherapy Slightly Inhibits Primary Tumor Growth but Promotes Spontaneous Metastasis

(2015) T. Voloshin et al.   MOLECULAR CANCER THERAPEUTICS

Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival

(2015) D Dayde et al.   ONCOGENE

Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy

(2015) Renata Silva et al.   PHARMACOLOGY & THERAPEUTICS

Quantitative interactome analysis reveals a chemoresistant edgotype

(2015) Juan D. Chavez et al.   Nature Communications

Integrative transcriptomics-based identification of cryptic drivers of taxol-resistance genes in ovarian carcinoma cells: Analysis of the androgen receptor

(2015) Nian-Kang Sun et al.   Oncotarget

Cetuximab enhanced the efficacy of chemotherapeutic agent in ABCB1/P-glycoprotein-overexpressing cancer cells

(2015) Fang Wang et al.   Oncotarget

Primary Pulmonary Mucoepidermoid Carcinoma: Histopathological and Moleculargenetic Studies of 26 Cases

(2015) Zhen Huo et al.   PLoS One

Targeting the Oncogenic MUC1-C Protein Inhibits Mutant EGFR-Mediated Signaling and Survival in Non-Small Cell Lung Cancer Cells

(2014) A. Kharbanda et al.   CLINICAL CANCER RESEARCH

MUC1: a multifaceted oncoprotein with a key role in cancer progression

(2014) Sritama Nath et al.   TRENDS IN MOLECULAR MEDICINE

Inhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells

(2013) Yasumitsu Uchida et al.   CANCER BIOLOGY & THERAPY

MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes

(2013) S Nath et al.   Oncogenesis

ABC transporters and their role in nucleoside and nucleotide drug resistance

(2012) Yu Fukuda et al.   BIOCHEMICAL PHARMACOLOGY

Cisplatin Selects for Multidrug-Resistant CD133+ Cells in Lung Adenocarcinoma by Activating Notch Signaling

(2012) Y.-P. Liu et al.   CANCER RESEARCH

Tyrosine Kinase Inhibitors Influence ABCG2 Expression in EGFR-Positive MDCK BCRP Cells via the PI3K/Akt Signaling Pathway

(2012) Anne Pick et al.   ChemMedChem

Treatment of metastatic cervical cancer: Future directions involving targeted agents

(2012) Ivan Diaz-Padilla et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Multidrug-resistant cells overexpressing P-glycoprotein are susceptible to DNA crosslinking agents due to attenuated Src/nuclear EGFR cascade-activated DNA repair activity

(2012) P-C Lee et al.   ONCOGENE

MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches

(2012) D W Kufe   ONCOGENE

ABC Proteins Protect the Human Body and Maintain Optimal Health

(2011) Kazumitsu UEDA   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

MUC1 induces metastasis in esophageal squamous cell carcinoma by upregulating matrix metalloproteinase 13

(2011) Qing Ye et al.   LABORATORY INVESTIGATION

Dependence on the MUC1-C Oncoprotein in Non-Small Cell Lung Cancer Cells

(2011) D. Raina et al.   MOLECULAR CANCER THERAPEUTICS

The Cytoplasmic Domain of MUC1 Induces Hyperplasia in the Mammary Gland and Correlates with Nuclear Accumulation of β-Catenin

(2011) Yuan Li et al.   PLoS One

Muc1 oncoprotein suppresses activation of the ARF-MDM2-p53 pathway

(2010) Deepak Raina et al.   CANCER BIOLOGY & THERAPY

MUC1 regulates nuclear localization and function of the epidermal growth factor receptor

(2010) B. G. Bitler et al.   JOURNAL OF CELL SCIENCE

Expression of mucin antigens (MUC1 and MUC16) as a prognostic factor for mucinous adenocarcinoma of the uterine cervix

(2010) Shinichi Togami et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Improving bioscience research reporting: ARRIVE-ing at a solution

(2010) C Kilkenny et al.   LABORATORY ANIMALS

Mitochondrial ABC proteins in health and disease

(2009) Ariane Zutz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

PSC833, cyclosporine analogue, downregulates MDR1 expression by activating JNK/c-Jun/AP-1 and suppressing NF-κB

(2009) H. Bark et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

MUC1-C Oncoprotein Functions as a Direct Activator of the Nuclear Factor- B p65 Transcription Factor

(2009) R. Ahmad et al.   CANCER RESEARCH

MUC1-Induced Transcriptional Programs Associated with Tumorigenesis Predict Outcome in Breast and Lung Cancer

(2009) N. N. Khodarev et al.   CANCER RESEARCH

MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment

(2009) S. P. Pitroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells

(2008) Xianling Guo et al.   BMC CANCER

MUC1 Expression Is Regulated by DNA Methylation and Histone H3 Lysine 9 Modification in Cancer Cells

(2008) N. Yamada et al.   CANCER RESEARCH