Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival

ARF tumor suppression in the nucleolus

(2014) Leonard B. Maggi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Ironing out VPS34 inhibition

(2014) Timothy Marsh et al.   NATURE CELL BIOLOGY

Mutation of TP53 and Alteration of p14arf Expression in EGFR- and KRAS-Mutated Lung Adenocarcinomas

(2013) Alexis B. Cortot et al.   Clinical Lung Cancer

Nuclear EGFR protein expression predicts poor survival in early stage non-small cell lung cancer

(2013) Anne M. Traynor et al.   LUNG CANCER

Receptor Tyrosine Kinases in the Nucleus

(2013) G. Carpenter et al.   Cold Spring Harbor Perspectives in Biology

shRNA-mediated knockdown of Bmi-1 inhibit lung adenocarcinoma cell migration and metastasis

(2012) Xiuxiang Meng et al.   LUNG CANCER

p14ARF inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway

(2012) P Ozenne et al.   ONCOGENE

EGFR Kinase Promotes Acquisition of Stem Cell-Like Properties: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma Stem Cells

(2012) Eric L. Abhold et al.   PLoS One

Where EGF Receptors Transmit Their Signals

(2012) N. L. Lill et al.   Science Signaling

Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family

(2012) Ying-Nai Wang et al.   Cell and Bioscience

EGFR Nuclear Translocation Modulates DNA Repair following Cisplatin and Ionizing Radiation Treatment

(2011) G. Liccardi et al.   CANCER RESEARCH

Epidermal growth factor increases LRF/Pokemon expression in human prostate cancer cells

(2011) Himanshu Aggarwal et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Nuclear Translocation of Epidermal Growth Factor Receptor by Akt-dependent Phosphorylation Enhances Breast Cancer-resistant Protein Expression in Gefitinib-resistant Cells

(2011) Wei-Chien Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Functional Nuclear Epidermal Growth Factor Receptor, Src and Stat3 Heteromeric Complex in Pancreatic Cancer Cells

(2011) Soumya Jaganathan et al.   PLoS One

Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654

(2010) Klaus Dittmann et al.   FEBS LETTERS

The ARF tumor suppressor: Structure, functions and status in cancer

(2010) Peggy Ozenne et al.   INTERNATIONAL JOURNAL OF CANCER

Cyclooxygenase-2 Is a Novel Transcriptional Target of the Nuclear EGFR-STAT3 and EGFRvIII-STAT3 Signaling Axes

(2010) H.-W. Lo et al.   MOLECULAR CANCER RESEARCH

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nuclear trafficking of the epidermal growth factor receptor family membrane proteins

(2010) Y-N Wang et al.   ONCOGENE

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

(2009) Anne Simonsen et al.   JOURNAL OF CELL BIOLOGY

Nuclear EGFR contributes to acquired resistance to cetuximab

(2009) C Li et al.   ONCOGENE

The regulation and function of Class III PI3Ks: novel roles for Vps34

(2008) Jonathan M. Backer   BIOCHEMICAL JOURNAL

Overexpression of Pokemon in non-small cell lung cancer and foreshowing tumor biological behavior as well as clinical results

(2008) Zhi-hong Zhao et al.   LUNG CANCER

Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer

(2008) Weiya Xia et al.   MOLECULAR CARCINOGENESIS

Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression

(2008) Liang-Yi Hung et al.   NUCLEIC ACIDS RESEARCH

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

(2008) J. S. Dovey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA