Latency-Associated Expression of Human Cytomegalovirus US28 Attenuates Cell Signaling Pathways To Maintain Latent Infection

Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein

(2017) B. A. Krishna et al.   Nature Communications

Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early-gene expression during latency to prevent T-cell recognition of latently infected cells

(2016) Betty Lau et al.   JOURNAL OF GENERAL VIROLOGY

The HCMV US28 vGPCR induces potent Gαq/PLC-β signaling in monocytes leading to increased adhesion to endothelial cells

(2016) Shu-en Wu et al.   VIROLOGY

Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication

(2016) Jason Buehler et al.   PLoS Pathogens

Transient activation of human cytomegalovirus lytic gene expression during latency allows cytotoxic T cell killing of latently infected cells

(2016) B. A. Krishna et al.   Scientific Reports

The Expression of Human Cytomegalovirus MicroRNA MiR-UL148D during Latent Infection in Primary Myeloid Cells Inhibits Activin A-triggered Secretion of IL-6

(2016) Betty Lau et al.   Scientific Reports

Cytomegalovirus Reactivation after Allogeneic Hematopoietic Stem Cell Transplantation is Associated with a Reduced Risk of Relapse in Patients with Acute Myeloid Leukemia Who Survived to Day 100 after Transplantation: The Japan Society for Hematopoietic Cell Transplantation Transplantation-related Complication Working Group

(2015) Katsuto Takenaka et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Human Cytomegalovirus US28 Is Important for Latent Infection of Hematopoietic Progenitor Cells

(2015) Monica S. Humby et al.   JOURNAL OF VIROLOGY

Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

(2015) J. S. Burg et al.   SCIENCE

Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch

(2015) Benjamin Rauwel et al.   eLife

Cellular defense against latent colonization foiled by human cytomegalovirus UL138 protein

(2015) S. H. Lee et al.   Science Advances

Alveolar Macrophages Isolated Directly From Human Cytomegalovirus (HCMV)–Seropositive Individuals Are Sites of HCMV Reactivation In Vivo

(2015) Emma Poole et al.   JOURNAL OF INFECTIOUS DISEASES

The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies?

(2014) Mark R Wills et al.   Cellular & Molecular Immunology

Human cytomegalovirus latency and reactivation in and beyond the myeloid lineage

(2014) John Sinclair et al.   Future Virology

Glucocorticosteroids trigger reactivation of human cytomegalovirus from latently infected myeloid cells and increase the risk for HCMV infection in D+R+ liver transplant patients

(2014) E. Van Damme et al.   JOURNAL OF GENERAL VIROLOGY

Latency-Associated Viral Interleukin-10 (IL-10) Encoded by Human Cytomegalovirus Modulates Cellular IL-10 and CCL8 Secretion during Latent Infection through Changes in the Cellular MicroRNA hsa-miR-92a

(2014) E. Poole et al.   JOURNAL OF VIROLOGY

Diverse Specificities, Phenotypes, and Antiviral Activities of Cytomegalovirus-Specific CD8+ T Cells

(2014) S. E. Jackson et al.   JOURNAL OF VIROLOGY

Herpesvirus-encoded GPCRs: neglected players in inflammatory and proliferative diseases?

(2014) Henry F. Vischer et al.   NATURE REVIEWS DRUG DISCOVERY

Mitogen and Stress Activated Kinases Act Co-operatively with CREB during the Induction of Human Cytomegalovirus Immediate-Early Gene Expression from Latency

(2014) Verity G. Kew et al.   PLoS Pathogens

The Myeloid Transcription Factor GATA-2 Regulates the Viral UL144 Gene during Human Cytomegalovirus Latency in an Isolate-Specific Manner

(2013) E. Poole et al.   JOURNAL OF VIROLOGY

Myeloblastic Cell Lines Mimic Some but Not All Aspects of Human Cytomegalovirus Experimental Latency Defined in Primary CD34+ Cell Populations

(2013) E. R. Albright et al.   JOURNAL OF VIROLOGY

Circulating Dendritic Cells Isolated from Healthy Seropositive Donors Are Sites of Human Cytomegalovirus Reactivation In Vivo

(2013) M. B. Reeves et al.   JOURNAL OF VIROLOGY

Latency-Associated Degradation of the MRP1 Drug Transporter During Latent Human Cytomegalovirus Infection

(2013) M. P. Weekes et al.   SCIENCE

Regulation of Human Cytomegalovirus Transcription in Latency: Beyond the Major Immediate-Early Promoter

(2013) Matthew Reeves et al.   Viruses-Basel

Cis and Trans Acting Factors Involved in Human Cytomegalovirus Experimental and Natural Latent Infection of CD14 (+) Monocytes and CD34 (+) Cells

(2013) Cyprian C. Rossetto et al.   PLoS Pathogens

A Myeloid Progenitor Cell Line Capable of Supporting Human Cytomegalovirus Latency and Reactivation, Resulting in Infectious Progeny

(2012) Christine M. O'Connor et al.   JOURNAL OF VIROLOGY

HCMV Protein LUNA Is Required for Viral Reactivation from Latently Infected Primary CD14+ Cells

(2012) Lisa R. Keyes et al.   PLoS One

US28 Is a Potent Activator of Phospholipase C during HCMV Infection of Clinically Relevant Target Cells

(2012) William E. Miller et al.   PLoS One

Constitutive ß-Catenin Signaling by the Viral Chemokine Receptor US28

(2012) Ellen V. Langemeijer et al.   PLoS One

Human cytomegalovirus latency alters the cellular secretome, inducing cluster of differentiation (CD)4+ T-cell migration and suppression of effector function

(2012) G. M. Mason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virally induced changes in cellular microRNAs maintain latency of human cytomegalovirus in CD34+ progenitors

(2011) E. Poole et al.   JOURNAL OF GENERAL VIROLOGY

HCMV-Encoded Chemokine Receptor US28 Mediates Proliferative Signaling Through the IL-6-STAT3 Axis

(2010) E. Slinger et al.   Science Signaling

Human cytomegalovirus immunity and immune evasion

(2010) Sarah E. Jackson et al.   VIRUS RESEARCH

The Human Cytomegalovirus-Encoded Chemokine Receptor US28 Promotes Angiogenesis and Tumor Formation via Cyclooxygenase-2

(2009) D. Maussang et al.   CANCER RESEARCH

Congenital cytomegalovirus (CMV) epidemiology and awareness

(2009) Michael J. Cannon   JOURNAL OF CLINICAL VIROLOGY

Analysis of latent viral gene expression in natural and experimental latency models of human cytomegalovirus and its correlation with histone modifications at a latent promoter

(2009) M. B. Reeves et al.   JOURNAL OF GENERAL VIROLOGY

Human cytomegalovirus-encoded chemokine receptor homolog US28 stimulates the major immediate early gene promoter/enhancer via the induction of CREB

(2009) Dong-Qing Wen et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Identification of TRIM23 as a Cofactor Involved in the Regulation of NF- B by Human Cytomegalovirus

(2009) E. Poole et al.   JOURNAL OF VIROLOGY

Differential Ligand Binding to a Human Cytomegalovirus Chemokine Receptor Determines Cell Type–Specific Motility

(2009) Jennifer Vomaske et al.   PLoS Pathogens

Constitutive serum response factor activation by the viral chemokine receptor homologue pUS28 is differentially regulated by Gαq/11 and Gα16

(2008) Barbara Moepps et al.   CELLULAR SIGNALLING