Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication

Human CytomegalovirusUL135andUL136Genes Are Required for Postentry Tropism in Endothelial Cells

(2015) Farah Bughio et al.   JOURNAL OF VIROLOGY

Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation during DNA synthesis

(2015) Janice Ortega et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions

(2015) Osnat Tirosh et al.   PLoS Pathogens

Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch

(2015) Benjamin Rauwel et al.   eLife

Quantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction

(2014) Michael P. Weekes et al.   CELL

Cytomegalovirus miRNAs Target Secretory Pathway Genes to Facilitate Formation of the Virion Assembly Compartment and Reduce Cytokine Secretion

(2014) Lauren M. Hook et al.   Cell Host & Microbe

HCMV pUL135 Remodels the Actin Cytoskeleton to Impair Immune Recognition of Infected Cells

(2014) Richard J. Stanton et al.   Cell Host & Microbe

Antagonistic Determinants Controlling Replicative and Latent States of Human Cytomegalovirus Infection

(2014) M. Umashankar et al.   JOURNAL OF VIROLOGY

Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh

(2014) Aurélien Rizk et al.   Nature Protocols

Viruses exploit the function of epidermal growth factor receptor

(2014) Kai Zheng et al.   REVIEWS IN MEDICAL VIROLOGY

Threshold-controlled ubiquitination of the EGFR directs receptor fate

(2013) Sara Sigismund et al.   EMBO JOURNAL

Coupling Image Restoration and Segmentation: A Generalized Linear Model/Bregman Perspective

(2013) Grégory Paul et al.   INTERNATIONAL JOURNAL OF COMPUTER VISION

An Endothelial Cell-Specific Requirement for the UL133-UL138 Locus of Human Cytomegalovirus for Efficient Virus Maturation

(2013) F. Bughio et al.   JOURNAL OF VIROLOGY

c-Cbl-Mediated Neddylation Antagonizes Ubiquitination and Degradation of the TGF-β Type II Receptor

(2013) Wei Zuo et al.   MOLECULAR CELL

Latency-Associated Degradation of the MRP1 Drug Transporter During Latent Human Cytomegalovirus Infection

(2013) M. P. Weekes et al.   SCIENCE

EGF receptor trafficking: consequences for signaling and cancer

(2013) Alejandra Tomas et al.   TRENDS IN CELL BIOLOGY

Human cytomegalovirus persistence

(2012) Felicia Goodrum et al.   CELLULAR MICROBIOLOGY

Interactions between Proteins Encoded within the Human CytomegalovirusUL133-UL138Locus

(2012) Alex Petrucelli et al.   JOURNAL OF VIROLOGY

Epidermal Growth Factor Receptor Is Essential for Toll-Like Receptor 3 Signaling

(2012) M. Yamashita et al.   Science Signaling

Antiviral Inhibition Targeting the HCMV Kinase pUL97 Requires pUL27-Dependent Degradation of Tip60 Acetyltransferase and Cell-Cycle Arrest

(2011) Justin M. Reitsma et al.   Cell Host & Microbe

Recycling of the Epidermal Growth Factor Receptor Is Mediated by a Novel Form of the Clathrin Adaptor Protein Eps15

(2011) Susan Chi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Latency-Associated UL138 Gene Product of Human Cytomegalovirus Sensitizes Cells to Tumor Necrosis Factor Alpha (TNF- ) Signaling by Upregulating TNF-  Receptor 1 Cell Surface Expression

(2011) C. Montag et al.   JOURNAL OF VIROLOGY

Human Cytomegalovirus Infection Maintains mTOR Activity and Its Perinuclear Localization during Amino Acid Deprivation

(2011) A. J. Clippinger et al.   JOURNAL OF VIROLOGY

Receptor Tyrosine Kinase Inhibitors Block Multiple Steps of Influenza A Virus Replication

(2011) N. Kumar et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Requires VP11/12 To Activate Src Family Kinase-Phosphoinositide 3-Kinase-Akt Signaling

(2011) M. J. Wagner et al.   JOURNAL OF VIROLOGY

Epstein-Barr Virus LMP1 Activates EGFR, STAT3, and ERK through Effects on PKC 

(2011) C.-P. Kung et al.   JOURNAL OF VIROLOGY

Spatial Relationships between Markers for Secretory and Endosomal Machinery in Human Cytomegalovirus-Infected Cells versus Those in Uninfected Cells

(2011) S. Das et al.   JOURNAL OF VIROLOGY

Feedback regulation of EGFR signalling: decision making by early and delayed loops

(2011) Roi Avraham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Novel Human Cytomegalovirus Locus Modulates Cell Type-Specific Outcomes of Infection

(2011) Mahadevaiah Umashankar et al.   PLoS Pathogens

Nature and Duration of Growth Factor Signaling through Receptor Tyrosine Kinases Regulates HSV-1 Latency in Neurons

(2010) Vladimir Camarena et al.   Cell Host & Microbe

PI3K-Dependent Upregulation of Mcl-1 by Human Cytomegalovirus Is Mediated by Epidermal Growth Factor Receptor and Inhibits Apoptosis in Short-Lived Monocytes

(2010) G. Chan et al.   JOURNAL OF IMMUNOLOGY

Rapamycin-Resistant mTORC1 Kinase Activity Is Required for Herpesvirus Replication

(2010) N. J. Moorman et al.   JOURNAL OF VIROLOGY

Stress-Inducible Alternative Translation Initiation of Human Cytomegalovirus Latency Protein pUL138

(2010) L. Grainger et al.   JOURNAL OF VIROLOGY

Inhibition of epidermal growth factor receptor (EGFR) expression by human cytomegalovirus correlates with an increase in the expression and binding of Wilms' Tumour 1 protein to the EGFR promoter

(2009) I. Jafferji et al.   JOURNAL OF GENERAL VIROLOGY

Inhibition of the phosphatidylinositol 3-kinase-Akt pathway enhances gamma-2 herpesvirus lytic replication and facilitates reactivation from latency

(2009) L. Peng et al.   JOURNAL OF GENERAL VIROLOGY

Characterization of a Novel Golgi Apparatus-Localized Latency Determinant Encoded by Human Cytomegalovirus

(2009) A. Petrucelli et al.   JOURNAL OF VIROLOGY

Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility

(2009) Gary Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cbl Controls EGFR Fate by Regulating Early Endosome Fusion

(2009) G. D. Visser Smit et al.   Science Signaling

HCMV-Encoded Glycoprotein M (UL100) Interacts with Rab11 Effector Protein FIP4

(2009) Magdalena A. Krzyzaniak et al.   TRAFFIC

Rhinovirus-Induced Major Airway Mucin Production Involves a Novel TLR3-EGFR–Dependent Pathway

(2008) Lingxiang Zhu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Human Cytomegalovirus Protein UL38 Inhibits Host Cell Stress Responses by Antagonizing the Tuberous Sclerosis Protein Complex

(2008) Nathaniel J. Moorman et al.   Cell Host & Microbe

Endocytic regulation of TGF-β signaling

(2008) Ye-Guang Chen   CELL RESEARCH

Epidermal Growth Factor Receptor Signaling to Erk1/2 and STATs Control the Intensity of the Epithelial Inflammatory Responses to Rhinovirus Infection

(2008) Kenneth Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human CMV infection of endothelial cells induces an angiogenic response through viral binding to EGF receptor and  1 and  3 integrins

(2008) G. L. Bentz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA