Biscarbene gold(i) complexes: structure–activity-relationships regarding antibacterial effects, cytotoxicity, TrxR inhibition and cellular bioavailability
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Title
Biscarbene gold(i) complexes: structure–activity-relationships regarding antibacterial effects, cytotoxicity, TrxR inhibition and cellular bioavailability
Authors
Keywords
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Journal
MedChemComm
Volume 8, Issue 8, Pages 1681-1689
Publisher
Royal Society of Chemistry (RSC)
Online
2017-06-27
DOI
10.1039/c7md00269f
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Note: Only part of the references are listed.- Determinants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD Investigation
- (2016) Carla Bazzicalupi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- Targeting antioxidant pathways with ferrocenylated N-heterocyclic carbene supported gold(i) complexes in A549 lung cancer cells
- (2016) J. F. Arambula et al. Chemical Science
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- N -heterocyclic carbenes (NHC) with 1,2,4-oxadiazole-substituents related to natural products: Synthesis, structure and potential antitumor activity of some corresponding gold(I) and silver(I) complexes
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- Gold(I) NHC-based homo- and heterobimetallic complexes: synthesis, characterization and evaluation as potential anticancer agents
- (2015) Benoît Bertrand et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis
- (2015) Michael B. Harbut et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A novel aminotriazole-based NHC complex for the design of gold(i) anti-cancer agents: synthesis and biological evaluation
- (2015) T. V. Serebryanskaya et al. MedChemComm
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- Auranofin Is an Apoptosis-Simulating Agent with in Vitro and in Vivo Anti-leishmanial Activity
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- A golden future in medicinal inorganic chemistry: the promise of anticancer gold organometallic compounds
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- Cover Picture: Champagne and Fireworks:Angewandte ChemieCelebrates Its Birthday (Angew. Chem. Int. Ed. 1/2013)
- (2012) Peter Gölitz ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione
- (2012) Jun Lu et al. FASEB JOURNAL
- Synthesis, Characterization, and in Vitro Studies of Bis[1,3-diethyl-4,5-diarylimidazol-2-ylidene]gold(I/III) Complexes
- (2012) Wukun Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target
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- (2009) Ingo Ott COORDINATION CHEMISTRY REVIEWS
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