Enantioselective catalytic β-amination through proton-coupled electron transfer followed by stereocontrolled radical–radical coupling

Proton-Coupled Electron Transfer in Photoredox Catalytic Reactions

(2017) Norbert Hoffmann   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Visible-Light-Mediated 5-exo -dig Cyclizations of Amidyl Radicals

(2017) Daniel Fernandez Reina et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Metal- and Reagent-Free Intramolecular Oxidative Amination of Tri- and Tetrasubstituted Alkenes

(2017) Peng Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-light excitation of iminium ions enables the enantioselective catalytic β-alkylation of enals

(2017) Mattia Silvi et al.   Nature Chemistry

Photocatalytic Cross-Dehydrogenative Amination Reactions between Phenols and Diarylamines

(2017) Yating Zhao et al.   ACS Catalysis

Synthetic Applications of Proton-Coupled Electron Transfer

(2016) Emily C. Gentry et al.   ACCOUNTS OF CHEMICAL RESEARCH

Single-Electron Transmetalation via Photoredox/Nickel Dual Catalysis: Unlocking a New Paradigm for sp3–sp2 Cross-Coupling

(2016) John C. Tellis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Free Radical Chemistry Enabled by Visible Light-Induced Electron Transfer

(2016) Daryl Staveness et al.   ACCOUNTS OF CHEMICAL RESEARCH

Electrocatalytic Generation of Amidyl Radicals for Olefin Hydroamidation: Use of Solvent Effects to Enable Anilide Oxidation

(2016) Lin Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amidinyl Radical Formation through Anodic N−H Bond Cleavage and Its Application in Aromatic C−H Bond Functionalization

(2016) Huai-Bo Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A visible-light photocatalytic N-radical cascade of hydrazones for the synthesis of dihydropyrazole-fused benzosultams

(2016) Quan-Qing Zhao et al.   CHEMICAL COMMUNICATIONS

Cutting-Edge and Time-Honored Strategies for Stereoselective Construction of C–N Bonds in Total Synthesis

(2016) Artur K. Mailyan et al.   CHEMICAL REVIEWS

Dual Catalysis Strategies in Photochemical Synthesis

(2016) Kazimer L. Skubi et al.   CHEMICAL REVIEWS

New amination strategies based on nitrogen-centered radical chemistry

(2016) Tao Xiong et al.   CHEMICAL SOCIETY REVIEWS

Visible light photoredox-controlled reactions of N-radicals and radical ions

(2016) Jia-Rong Chen et al.   CHEMICAL SOCIETY REVIEWS

A Rhodium Catalyst Superior to Iridium Congeners for Enantioselective Radical Amination Activated by Visible Light

(2016) Xiaodong Shen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Visible-Light-Induced Direct Oxidative C−H Amidation of Heteroarenes with Sulfonamides

(2016) Kun Tong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organophotocatalytic Generation of N- and O-Centred Radicals Enables Aerobic Oxyamination and Dioxygenation of Alkenes

(2016) Xiao-Qiang Hu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Expanding the family of bis-cyclometalated chiral-at-metal rhodium(iii) catalysts with a benzothiazole derivative

(2016) Jiajia Ma et al.   DALTON TRANSACTIONS

Oxindole: A chemical prism carrying plethora of therapeutic benefits

(2016) Maninder Kaur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Unusual Amino Acids in Medicinal Chemistry

(2016) Mark A. T. Blaskovich   JOURNAL OF MEDICINAL CHEMISTRY

Independence from the Sequence of Single-Electron Transfer of Photoredox Process in Redox-Neutral Asymmetric Bond-Forming Reaction

(2016) Tomohito Kizu et al.   JOURNAL OF ORGANIC CHEMISTRY

Photoredox Catalysis in Organic Chemistry

(2016) Megan H. Shaw et al.   JOURNAL OF ORGANIC CHEMISTRY

Visible-Light-Mediated Synthesis of Amidyl Radicals: Transition-Metal-Free Hydroamination and N-Arylation Reactions

(2016) Jacob Davies et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Catalysis with Organic Azides and Diazo Compounds Initiated by Photoinduced Electron Transfer

(2016) Xiaoqiang Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amide-directed photoredox-catalysed C–C bond formation at unactivated sp3 C–H bonds

(2016) John C. K. Chu et al.   NATURE

Catalytic alkylation of remote C–H bonds enabled by proton-coupled electron transfer

(2016) Gilbert J. Choi et al.   NATURE

Aza-Michael Addition of Imidazole Analogues

(2016) Katarzyna Błażewska et al.   SYNTHESIS-STUTTGART

Catalytic N-radical cascade reaction of hydrazones by oxidative deprotonation electron transfer and TEMPO mediation

(2016) Xiao-Qiang Hu et al.   Nature Communications

Catalytic C–N Bond-Forming Reactions Enabled by Proton-Coupled Electron Transfer Activation of Amide N–H Bonds

(2016) Lucas Q. Nguyen et al.   ACS Catalysis

Asymmetric Radical-Radical Cross-Coupling through Visible-Light-Activated Iridium Catalysis

(2015) Chuanyong Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-Light-Mediated Generation of Nitrogen-Centered Radicals: Metal-Free Hydroimination and Iminohydroxylation Cyclization Reactions

(2015) Jacob Davies et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Proton-Coupled Electron Transfer Reactions Catalysed by 3 d Metal Complexes

(2015) Inke Siewert   CHEMISTRY-A EUROPEAN JOURNAL

Regiospecific Intermolecular Aminohydroxylation of Olefins by Photoredox Catalysis

(2015) Kazuki Miyazawa et al.   CHEMISTRY-A EUROPEAN JOURNAL

Spirooxindoles: Promising scaffolds for anticancer agents

(2015) Bin Yu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synergistic Catalysis of Ionic Brønsted Acid and Photosensitizer for a Redox Neutral Asymmetric α-Coupling of N-Arylaminomethanes with Aldimines

(2015) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Olefin Hydroamidation Enabled by Proton-Coupled Electron Transfer

(2015) David C. Miller et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Alkene Carboaminations Enabled by Oxidative Proton-Coupled Electron Transfer

(2015) Gilbert J. Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Proton-Coupled Electron Transfer: Moving Together and Charging Forward

(2015) Sharon Hammes-Schiffer   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The stability of nitrogen-centered radicals

(2015) Johnny Hioe et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Lewis acid catalysis directed by octahedral rhodium centrochirality

(2015) Chuanyong Wang et al.   Chemical Science

The Oxime Portmanteau Motif: Released Heteroradicals Undergo Incisive EPR Interrogation and Deliver Diverse Heterocycles

(2014) John C. Walton   ACCOUNTS OF CHEMICAL RESEARCH

Photocatalytic Generation of N-Centered Hydrazonyl Radicals:  A Strategy for Hydroamination of β,γ-Unsaturated Hydrazones

(2014) Xiao-Qiang Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biochemistry and Theory of Proton-Coupled Electron Transfer

(2014) Agostino Migliore et al.   CHEMICAL REVIEWS

A general overview of the organocatalytic intramolecular aza-Michael reaction

(2014) María Sánchez-Roselló et al.   CHEMICAL SOCIETY REVIEWS

Electrochemical Intramolecular Aminooxygenation of Unactivated Alkenes

(2014) Fan Xu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Proton-Coupled Electron Transfer in Molecular Electrocatalysis: Theoretical Methods and Design Principles

(2014) Brian H. Solis et al.   INORGANIC CHEMISTRY

Peptides Containing β-Amino Acid Patterns: Challenges and Successes in Medicinal Chemistry

(2014) Chiara Cabrele et al.   JOURNAL OF MEDICINAL CHEMISTRY

N-Acyloxyphthalimides as Nitrogen Radical Precursors in the Visible Light Photocatalyzed Room Temperature C–H Amination of Arenes and Heteroarenes

(2014) Laura J. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Catalysis with Substitutionally Labile yet Stereochemically Stable Chiral-at-Metal Iridium(III) Complex

(2014) Haohua Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Free radicals under control

(2014) Bridgette A. Barry   Nature Chemistry

N-Aminopyridinium Salts as Precursors for N-Centered Radicals – Direct Amidation of Arenes and Heteroarenes

(2014) Tobias W. Greulich et al.   ORGANIC LETTERS

A Dual-Catalysis Approach to Enantioselective [2 + 2] Photocycloadditions Using Visible Light

(2014) J. Du et al.   SCIENCE

Proton-Coupled Electron Transfer in Organic Synthesis: Novel Homolytic Bond Activations and Catalytic Asymmetric Reactions with Free Radicals

(2014) Robert Knowles et al.   SYNLETT

Visible-light radical reaction designed by Ru- and Ir-based photoredox catalysis

(2014) Takashi Koike et al.   Inorganic Chemistry Frontiers

Proton-Coupled Electron Transfer with Photoexcited Metal Complexes

(2013) Oliver S. Wenger   ACCOUNTS OF CHEMICAL RESEARCH

Some aspects of radical chemistry in the assembly of complex molecular architectures

(2013) Béatrice Quiclet-Sire et al.   Beilstein Journal of Organic Chemistry

Synthesis of Carbocyclic and Heterocyclic β-Aminocarboxylic Acids

(2013) Loránd Kiss et al.   CHEMICAL REVIEWS

Cyclization Reactions of Anode-Generated Amidyl Radicals

(2013) Hai-Chao Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Direct α-Amination of Aldehydes via a Photoredox Mechanism: A Strategy for Asymmetric Amine Fragment Coupling

(2013) Giuseppe Cecere et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Photoredox Catalysis Enabled by Proton-Coupled Electron Transfer: Development of an Asymmetric Aza-Pinacol Cyclization

(2013) Lydia J. Rono et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoredox Activation for the Direct  -Arylation of Ketones and Aldehydes

(2013) M. T. Pirnot et al.   SCIENCE

Theory of multiple proton–electron transfer reactions and its implications for electrocatalysis

(2013) Marc T. M. Koper   Chemical Science

Synthesis and applications of masked oxo-sulfinamides in asymmetric synthesis

(2012) Ramakrishna Edupuganti et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Photocatalytic [2 + 2] Cycloadditions of Enones with Cleavable Redox Auxiliaries

(2012) Elizabeth L. Tyson et al.   ORGANIC LETTERS

Crossed intermolecular [2 + 2] cycloaddition of styrenes by visible light photocatalysis

(2012) Michael A. Ischay et al.   Chemical Science

Catalytic Enantioselective Formation of C−C Bonds by Addition to Imines and Hydrazones: A Ten-Year Update

(2011) Shu̅ Kobayashi et al.   CHEMICAL REVIEWS

Trichlorosilane mediated asymmetric reductions of the CN bond

(2011) Simon Jones et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Unexpected Inversions in Asymmetric Reactions: Reactions with Chiral Metal Complexes, Chiral Organocatalysts, and Heterogeneous Chiral Catalysts

(2009) Mihály Bartók   CHEMICAL REVIEWS

From Azides to Nitrogen-Centered Radicals: Applications of Azide Radical Chemistry to Organic Synthesis

(2009) Matteo Minozzi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Asymmetric Aza-Michael Additions

(2009) Dieter Enders et al.   CHEMISTRY-A EUROPEAN JOURNAL

Handing over the baton: Connecting medicinal chemistry with process R&D

(2009) H.-J. Federsel   DRUG NEWS & PERSPECTIVES

Crossed Intermolecular [2+2] Cycloadditions of Acyclic Enones via Visible Light Photocatalysis

(2009) Juana Du et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances and applications in asymmetric aza-Michael addition chemistry

(2009) Palakodety Radha Krishna et al.   TETRAHEDRON

Bifunctional Asymmetric Catalysis: Cooperative Lewis Acid/Base Systems

(2008) Daniel H. Paull et al.   ACCOUNTS OF CHEMICAL RESEARCH

Recent progress in the generation and use of nitrogen-centred radicals

(2008) Samir Z. Zard   CHEMICAL SOCIETY REVIEWS

Highly Enantioselective Synthesis of β-Amino Acid Derivatives by the Lewis Base Catalyzed Hydrosilylation of β-Enamino Esters

(2008) Hong-Jie Zheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Intramolecular Anodic Olefin Coupling Reactions: The Use of a Nitrogen Trapping Group

(2008) Hai-Chao Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Visible Light Photocatalysis of [2+2] Enone Cycloadditions

(2008) Michael A. Ischay et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY