Cyclometalated Ir(iii) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy

Visible-Light-Induced Annihilation of Tumor Cells with Platinum-Porphyrin Conjugates

(2014) Anu Naik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Potent Oxidant Anticancer Activity of Organoiridium Catalysts

(2014) Zhe Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photo-induced uncaging of a specific Re(i) organometallic complex in living cells

(2014) Anna Leonidova et al.   Chemical Science

Erasers of Histone Acetylation: The Histone Deacetylase Enzymes

(2014) E. Seto et al.   Cold Spring Harbor Perspectives in Biology

De Novo Generation of Singlet Oxygen and Ammine Ligands by Photoactivation of a Platinum Anticancer Complex

(2013) Yao Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mitochondria-targeting cyclometalated iridium(III)–PEG complexes with tunable photodynamic activity

(2013) Steve Po-Yam Li et al.   BIOMATERIALS

Histone-Deacetylase-Targeted Fluorescent Ruthenium(II) Polypyridyl Complexes as Potent Anticancer Agents

(2013) Rui-Rong Ye et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhenium Complexes with Visible-Light-Induced Anticancer Activity

(2013) Anja Kastl et al.   ChemMedChem

Bioactive iridium and rhodium complexes as therapeutic agents

(2013) Chung-Hang Leung et al.   COORDINATION CHEMISTRY REVIEWS

Efficient new constructs against triple negative breast cancer cells: synthesis and preliminary biological study of ferrocifen–SAHA hybrids and related species

(2013) José de Jesús Cázares Marinero et al.   DALTON TRANSACTIONS

Towards cancer cell-specific phototoxic organometallic rhenium(i) complexes

(2013) Anna Leonidova et al.   DALTON TRANSACTIONS

Exploitation of Long-Lived 3IL Excited States for Metal–Organic Photodynamic Therapy: Verification in a Metastatic Melanoma Model

(2013) Richard Lincoln et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cellular Toxicity Induced by the Photorelease of a Caged Bioactive Molecule: Design of a Potential Dual-Action Ru(II) Complex

(2013) Mark A. Sgambellone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gemcitabine–Coumarin–Biotin Conjugates: A Target Specific Theranostic Anticancer Prodrug

(2013) Sukhendu Maiti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, Arylsulfamide, and Arylsulfamate Conjugates for Selective Targeting of Human Carbonic Anhydrase IX

(2012) Daniel Can et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cyclometalated iridium(iii) polypyridine dibenzocyclooctyne complexes as the first phosphorescent bioorthogonal probes

(2012) Kenneth Kam-Wing Lo et al.   CHEMICAL COMMUNICATIONS

Photofunctional triplet excited states of cyclometalated Ir(iii) complexes: beyond electroluminescence

(2012) Youngmin You et al.   CHEMICAL SOCIETY REVIEWS

Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents

(2012) Brock S. Howerton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Dual anticancer activity in a single compound: visible-light-induced apoptosis by an antiangiogenic iridium complex

(2011) Anja Kastl et al.   CHEMICAL COMMUNICATIONS

Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors

(2011) Li Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphorescent Sensor for Robust Quantification of Copper(II) Ion

(2011) Youngmin You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Click JAHAs: conformationally restricted ferrocene-based histone deacetylase inhibitors

(2011) John Spencer et al.   MedChemComm

Synthesis and Biological Evaluation of JAHAs: Ferrocene-Based Histone Deacetylase Inhibitors

(2011) John Spencer et al.   ACS Medicinal Chemistry Letters

Iridium Complex with Antiangiogenic Properties

(2010) Alexander Wilbuer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization

(2010) Jonathan P. Celli et al.   CHEMICAL REVIEWS

Tuning Photosensitized Singlet Oxygen Generation Efficiency of Novel Aza-BODIPY Dyes

(2010) Nagappanpillai Adarsh et al.   ORGANIC LETTERS

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

EM011 activates a survivin-dependent apoptotic program in human non-small cell lung cancer cells

(2009) Prasanthi Karna et al.   Molecular Cancer

Histone Deacetylase Inhibitors Modify Pancreatic Cell Fate Determination and Amplify Endocrine Progenitors

(2008) C. Haumaitre et al.   MOLECULAR AND CELLULAR BIOLOGY

Caspases in apoptosis and beyond

(2008) J Li et al.   ONCOGENE