Identification of new quorum sensing autoinducer binding partners in Pseudomonas aeruginosa using photoaffinity probes

The requirements at the C-3 position of alkylquinolones for signalling in Pseudomonas aeruginosa

(2017) Rachel Shanahan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The Approach to Pseudomonas aeruginosa in Cystic Fibrosis

(2016) Jaideep S. Talwalkar et al.   CLINICS IN CHEST MEDICINE

A new Pseudomonas quinolone signal (PQS) binding partner: MexG

(2016) James T. Hodgkinson et al.   Chemical Science

The increasing threat of Pseudomonas aeruginosa high-risk clones

(2015) Antonio Oliver et al.   DRUG RESISTANCE UPDATES

Photoaffinity labeling in target- and binding-site identification

(2015) Ewan Smith et al.   Future Medicinal Chemistry

Cystic fibrosis microbiology: Advances in antimicrobial therapy

(2015) Valerie Waters et al.   Journal of Cystic Fibrosis

Pseudomonas aeruginosa in hospital water systems: biofilms, guidelines, and practicalities

(2015) J. Walker et al.   JOURNAL OF HOSPITAL INFECTION

Small Molecule Disruption of Quorum Sensing Cross-Regulation in Pseudomonas aeruginosa Causes Major and Unexpected Alterations to Virulence Phenotypes

(2015) Michael A. Welsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nosocomial Infections and Microbiologic Spectrum after Major Elective Surgery of the Pancreas, Liver, Stomach, and Esophagus

(2015) Olof Jannasch et al.   Surgical Infections

Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation

(2014) Craig S. McKay et al.   CHEMISTRY & BIOLOGY

The PqsR and RhlR Transcriptional Regulators Determine the Level of Pseudomonas Quinolone Signal Synthesis in Pseudomonas aeruginosa by Producing Two Different pqsABCDE mRNA Isoforms

(2014) S. Brouwer et al.   JOURNAL OF BACTERIOLOGY

Ligand Binding Kinetics of the Quorum Sensing Regulator PqsR

(2013) Martin Welch et al.   BIOCHEMISTRY

Species selective diazirine positioning in tag-free photoactive quorum sensing probes

(2013) Luba Dubinsky et al.   CHEMICAL COMMUNICATIONS

Bioorthogonal chemistry: strategies and recent developments

(2013) Carlo P. Ramil et al.   CHEMICAL COMMUNICATIONS

The End of an Old Hypothesis: The Pseudomonas Signaling Molecules 4-Hydroxy-2-Alkylquinolines Derive from Fatty Acids, Not 3-Ketofatty Acids

(2013) Carlos Eduardo Dulcey et al.   CHEMISTRY & BIOLOGY

Recent Advances in Target Characterization and Identification by Photoaffinity Probes

(2013) Jitapa Sumranjit et al.   MOLECULES

Structural Basis for Native Agonist and Synthetic Inhibitor Recognition by the Pseudomonas aeruginosa Quorum Sensing Regulator PqsR (MvfR)

(2013) Aravindan Ilangovan et al.   PLoS Pathogens

Pseudomonas aeruginosa: new insights into pathogenesis and host defenses

(2013) Shaan L. Gellatly et al.   Pathogens and Disease

Tandem photoaffinity labeling–bioorthogonal conjugation in medicinal chemistry

(2012) David J. Lapinsky   BIOORGANIC & MEDICINAL CHEMISTRY

Quorum sensing modulates colony morphology through alkyl quinolones in Pseudomonas aeruginosa

(2012) Rashmi Gupta et al.   BMC MICROBIOLOGY

Discovery of Antagonists of PqsR, a Key Player in 2-Alkyl-4-quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

(2012) Cenbin Lu et al.   CHEMISTRY & BIOLOGY

Pseudomonas aeruginosa outbreaks in the neonatal intensive care unit - a systematic review of risk factors and environmental sources

(2012) J. M. C. Jefferies et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors

(2012) Michael P. Storz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Multiple Signaling Systems Regulating Virulence in Pseudomonas aeruginosa

(2012) P. Nadal Jimenez et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Structure–function analysis of the C-3 position in analogues of microbial behavioural modulators HHQ and PQS

(2012) F. Jerry Reen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria

(2012) Warren R.J.D. Galloway et al.   TRENDS IN MICROBIOLOGY

Pyocyanin effects on respiratory epithelium: relevance in Pseudomonas aeruginosa airway infections

(2012) Balázs Rada et al.   TRENDS IN MICROBIOLOGY

Role of Intracellular Proteases in the Antibiotic Resistance, Motility, and Biofilm Formation of Pseudomonas aeruginosa

(2011) Lucía Fernández et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Diazirine based photoaffinity labeling

(2011) Luba Dubinsky et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Biosynthesis of 2-Alkyl-4(1H)-Quinolones in Pseudomonas aeruginosa: Potential for Therapeutic Interference with Pathogenicity

(2011) Dominik Pistorius et al.   CHEMBIOCHEM

Crystal structure of QscR, a Pseudomonas aeruginosa quorum sensing signal receptor

(2011) M. J. Lintz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolism and function of phenazines in bacteria: impacts on the behavior of bacteria in the environment and biotechnological processes

(2010) Leland S. Pierson et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Quorum Sensing in Gram-Negative Bacteria: Small-Molecule Modulation of AHL and AI-2 Quorum Sensing Pathways

(2010) Warren R. J. D. Galloway et al.   CHEMICAL REVIEWS

Structure-Activity Analysis of the Pseudomonas Quinolone Signal Molecule

(2010) J. Hodgkinson et al.   JOURNAL OF BACTERIOLOGY

Quorum sensing in bacterial virulence

(2010) L. C. M. Antunes et al.   MICROBIOLOGY-SGM

Structure of PqsD, aPseudomonasQuinolone Signal Biosynthetic Enzyme, in Complex with Anthranilate

(2009) Asim K. Bera et al.   BIOCHEMISTRY

Structural Requirements of the Pseudomonas Quinolone Signal for Membrane Vesicle Stimulation

(2009) L. Mashburn-Warren et al.   JOURNAL OF BACTERIOLOGY

Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria

(2008) Grant D. Geske et al.   CHEMICAL SOCIETY REVIEWS

PqsD Is Responsible for the Synthesis of 2,4-Dihydroxyquinoline, an Extracellular Metabolite Produced byPseudomonas aeruginosa

(2008) Yong-Mei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Functionalization of a Genetically Encoded Alkene-Containing Protein via “Photoclick Chemistry” in Bacterial Cells

(2008) Wenjiao Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY