Peptide/Cas9 nanostructures for ribonucleoprotein cell membrane transport and gene edition

Cell-penetrating peptides (CPPs): From delivery of nucleic acids and antigens to transduction of engineered nucleases for application in transgenesis

(2017) Gandhi Rádis-Baptista et al.   JOURNAL OF BIOTECHNOLOGY

Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide

(2017) Misao Akishiba et al.   Nature Chemistry

In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni

(2017) Eunji Kim et al.   Nature Communications

Hydrazone-modulated peptides for efficient gene transfection

(2017) Iria Louzao et al.   Journal of Materials Chemistry B

Anisotropic Self-Assembly of Hairy Inorganic Nanoparticles

(2016) Chenglin Yi et al.   ACCOUNTS OF CHEMICAL RESEARCH

In Situ Functionalized Polymers for siRNA Delivery

(2016) Juan M. Priegue et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CRISPR/Cas9 in Genome Editing and Beyond

(2016) Haifeng Wang et al.   Annual Review of Biochemistry

Improved delivery of Cas9 protein/gRNA complexes using lipofectamine CRISPRMAX

(2016) Xin Yu et al.   BIOTECHNOLOGY LETTERS

Surveying the Delivery Methods of CRISPR/Cas9 for ex vivo Mammalian Cell Engineering

(2016) William J. Kelton et al.   CHIMIA

The discovery of CRISPR in archaea and bacteria

(2016) Francisco J. M. Mojica et al.   FEBS Journal

In Vivo Delivery Systems for Therapeutic Genome Editing

(2016) Luyao Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Applications of CRISPR technologies in research and beyond

(2016) Rodolphe Barrangou et al.   NATURE BIOTECHNOLOGY

Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles

(2016) Ming Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the Origin of CRISPR-Cas Technology: From Prokaryotes to Mammals

(2016) Francisco J.M. Mojica et al.   TRENDS IN MICROBIOLOGY

General and programmable synthesis of hybrid liposome/metal nanoparticles

(2016) J.-H. Lee et al.   Science Advances

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

(2015) Wujin Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Intracellular Delivery of Native Proteins

(2015) Diego S. D’Astolfo et al.   CELL

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

(2015) Bernd Zetsche et al.   CELL

Peptide self-assembly for nanomaterials: the old new kid on the block

(2015) Emiliana De Santis et al.   CHEMICAL SOCIETY REVIEWS

Discovery and Characterization of a Peptide That Enhances Endosomal Escape of Delivered Proteins in Vitro and in Vivo

(2015) Margie Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vivo genome editing using Staphylococcus aureus Cas9

(2015) F. Ann Ran et al.   NATURE

An updated evolutionary classification of CRISPR–Cas systems

(2015) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA

(2014) S. Ramakrishna et al.   GENOME RESEARCH

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

(2014) S. Kim et al.   GENOME RESEARCH

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

(2014) John A Zuris et al.   NATURE BIOTECHNOLOGY

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Dynamic Amphiphile Libraries To Screen for the “Fragrant” Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts

(2013) Charlotte Gehin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

(2013) Kevin M Esvelt et al.   NATURE METHODS

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Arginine Topology Controls Escape of Minimally Cationic Proteins from Early Endosomes to the Cytoplasm

(2012) Jacob S. Appelbaum et al.   CHEMISTRY & BIOLOGY

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

(2012) G. Gasiunas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

State-of-the-art gene-based therapies: the road ahead

(2011) Mark A. Kay   NATURE REVIEWS GENETICS