Hydrazone-modulated peptides for efficient gene transfection

Histidine-enriched multifunctional peptide vectors with enhanced cellular uptake and endosomal escape for gene delivery

(2017) Zhao Meng et al.   Journal of Materials Chemistry B

Role of Cell Membrane–Vector Interactions in Successful Gene Delivery

(2016) Sriram Vaidyanathan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Peptides for nucleic acid delivery

(2016) Taavi Lehto et al.   ADVANCED DRUG DELIVERY REVIEWS

In Situ Functionalized Polymers for siRNA Delivery

(2016) Juan M. Priegue et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Versatile Supramolecular Gene Vector Based on Host–Guest Interaction

(2016) Jia Liu et al.   BIOCONJUGATE CHEMISTRY

Plasmid DNA delivery by arginine-rich cell-penetrating peptides containing unnatural amino acids

(2016) Takuma Kato et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Bioactive clusters promoting cell penetration and nucleic acid complexation for drug and gene delivery applications: from designed to self-assembled and responsive systems

(2016) Eline Bartolami et al.   CHEMICAL COMMUNICATIONS

Peptide self-assembly: thermodynamics and kinetics

(2016) Juan Wang et al.   CHEMICAL SOCIETY REVIEWS

Activation of Cell-Penetrating Peptides with Ionpair−π Interactions and Fluorophiles

(2016) Nicolas Chuard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strained Cyclic Disulfides Enable Cellular Uptake by Reacting with the Transferrin Receptor

(2016) Daniel Abegg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Overcoming Gene-Delivery Hurdles: Physiological Considerations for Nonviral Vectors

(2016) Andrew B. Hill et al.   TRENDS IN BIOTECHNOLOGY

The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery

(2016) Francesco Cardarelli et al.   Scientific Reports

Delivery of therapeutic oligonucleotides with cell penetrating peptides

(2015) Prisca Boisguérin et al.   ADVANCED DRUG DELIVERY REVIEWS

Dynamic Expression of DNA Complexation with Self-assembled Biomolecular Clusters

(2015) Eline Bartolami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ring Tension Applied to Thiol-Mediated Cellular Uptake

(2015) Giulio Gasparini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cellular uptake: lessons from supramolecular organic chemistry

(2015) Giulio Gasparini et al.   CHEMICAL COMMUNICATIONS

Therapeutic genome editing: prospects and challenges

(2015) David Benjamin Turitz Cox et al.   NATURE MEDICINE

Mechanism Matters: A Taxonomy of Cell Penetrating Peptides

(2015) W. Berkeley Kauffman et al.   TRENDS IN BIOCHEMICAL SCIENCES

Designer lipids for drug delivery: From heads to tails

(2014) Aditya G. Kohli et al.   JOURNAL OF CONTROLLED RELEASE

Cellular Uptake of Substrate-Initiated Cell-Penetrating Poly(disulfide)s

(2014) Giulio Gasparini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fundamental Molecular Mechanism for the Cellular Uptake of Guanidinium-Rich Molecules

(2014) Henry D. Herce et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

mRNA-based therapeutics — developing a new class of drugs

(2014) Ugur Sahin et al.   NATURE REVIEWS DRUG DISCOVERY

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Cationic liposome–nucleic acid complexes for gene delivery and gene silencing

(2014) Cyrus R. Safinya et al.   NEW JOURNAL OF CHEMISTRY

Single-Nucleotide-Resolution DNA Differentiation by Pattern Generation in Lipid Bilayer Membranes

(2014) Juan M. Priegue et al.   Small

Enzyme-Triggered PEGylated pDNA-Nanoparticles for Controlled Release of pDNA in Tumors

(2013) Peerada Yingyuad et al.   BIOCONJUGATE CHEMISTRY

Dynamic Amphiphile Libraries To Screen for the “Fragrant” Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts

(2013) Charlotte Gehin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Helical poly(arginine) mimics with superior cell-penetrating and molecular transporting properties

(2013) Haoyu Tang et al.   Chemical Science

Arginine clustering on calix[4]arene macrocycles for improved cell penetration and DNA delivery

(2013) Valentina Bagnacani et al.   Nature Communications

Peptide Vectors for the Nonviral Delivery of Nucleic Acids

(2012) Jan Hoyer et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of an Enlarged Library of Dynamic DNA Activators with Oxime, Disulfide and Hydrazone Bridges

(2012) Javier Montenegro et al.   CHEMISTRY-A EUROPEAN JOURNAL

In Vivo Gene Delivery by Nonviral Vectors: Overcoming Hurdles?

(2012) Yuan Zhang et al.   MOLECULAR THERAPY

Efficient Intracellular Delivery of Nucleic Acid Pharmaceuticals Using Cell-Penetrating Peptides

(2011) Ikuhiko Nakase et al.   ACCOUNTS OF CHEMICAL RESEARCH

Protein transduction domain delivery of therapeutic macromolecules

(2011) Arjen van den Berg et al.   CURRENT OPINION IN BIOTECHNOLOGY

Gene therapy finds its niche

(2011) Cormac Sheridan   NATURE BIOTECHNOLOGY

State-of-the-art gene-based therapies: the road ahead

(2011) Mark A. Kay   NATURE REVIEWS GENETICS

Comprehensive screening of octopus amphiphiles as DNA activators in lipid bilayers: implications on transport, sensing and cellular uptake

(2011) Javier Montenegro et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthetic polyion-counterion transport systems in polymersomes and gels

(2011) Javier Montenegro et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Anionic Activators for Differential Sensing with Cell-Penetrating Peptides

(2010) Javier Montenegro et al.   Chemistry-An Asian Journal

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE