Optical control of AMPA receptors using a photoswitchable quinoxaline-2,3-dione antagonist

AzoCholine Enables Optical Control of Alpha 7 Nicotinic Acetylcholine Receptors in Neural Networks

(2015) Arunas Damijonaitis et al.   ACS Chemical Neuroscience

Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death

(2015) Malgorzata Borowiak et al.   CELL

Controlling ionotropic and metabotropic glutamate receptors with light: principles and potential

(2015) Andreas Reiner et al.   CURRENT OPINION IN PHARMACOLOGY

Optical control of NMDA receptors with a diffusible photoswitch

(2015) Laura Laprell et al.   Nature Communications

Acetylcholinesterase Inhibitors with Photoswitchable Inhibition of β-Amyloid Aggregation

(2014) Xinyu Chen et al.   ACS Chemical Neuroscience

A Photochromic Agonist for μ-Opioid Receptors

(2014) Matthias Schönberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Optical Control of Acetylcholinesterase with a Tacrine Switch

(2014) Johannes Broichhagen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photopharmacology: Beyond Proof of Principle

(2014) Willem A. Velema et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An allosteric modulator to control endogenous G protein-coupled receptors with light

(2014) Silvia Pittolo et al.   Nature Chemical Biology

Restoring Visual Function to Blind Mice with a Photoswitch that Exploits Electrophysiological Remodeling of Retinal Ganglion Cells

(2014) Ivan Tochitsky et al.   NEURON

Chromo-pharmacophores: photochromic diarylmaleimide inhibitors for sirtuins

(2014) C. Falenczyk et al.   Chemical Science

Optical control of insulin release using a photoswitchable sulfonylurea

(2014) Johannes Broichhagen et al.   Nature Communications

Exploiting Protein Symmetry To Design Light-Controllable Enzyme Inhibitors

(2013) Bernd Reisinger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches

(2013) Wiktor Szymański et al.   CHEMICAL REVIEWS

A Photochromic Agonist of AMPA Receptors

(2012) Philipp Stawski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Light-Controlled Tools

(2012) Clara Brieke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances towards azobenzene-based light-driven real-time information-transmitting materials

(2012) Jaume García-Amorós et al.   Beilstein Journal of Organic Chemistry

AMPA receptors as drug targets in neurological disease - advantages, caveats, and future outlook

(2012) Philip K.-Y. Chang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Discovery of 2-(2-Oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (Perampanel): A Novel, Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropanoic Acid (AMPA) Receptor Antagonist

(2012) Shigeki Hibi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rapid optical control of nociception with an ion-channel photoswitch

(2012) Alexandre Mourot et al.   NATURE METHODS

Photochemical Restoration of Visual Responses in Blind Mice

(2012) Aleksandra Polosukhina et al.   NEURON

Optochemical Genetics

(2011) Timm Fehrentz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Azobenzene photoswitches for biomolecules

(2011) Andrew A. Beharry et al.   CHEMICAL SOCIETY REVIEWS

Pharmacology of ionotropic glutamate receptors: A structural perspective

(2010) Philipp Stawski et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

(2009) Alexander I. Sobolevsky et al.   NATURE

Kainate receptors: Pharmacology, function and therapeutic potential

(2008) David E. Jane et al.   NEUROPHARMACOLOGY