Liver tissue engineering in the evaluation of drug safety

Hard Top Soft Bottom Microfluidic Devices for Cell Culture and Chemical Analysis

(2009) Geeta Mehta et al.   ANALYTICAL CHEMISTRY

Human hepatocyte functions in a crossed hollow fiber membrane bioreactor

(2009) Loredana De Bartolo et al.   BIOMATERIALS

Quantitative inference of cellular parameters from microfluidic cell culture systems

(2009) Khamir Mehta et al.   BIOTECHNOLOGY AND BIOENGINEERING

Two Key Challenges for Effective Adenovirus-Mediated Liver Gene Therapy:Innate Immune Responses and Hepatocyte-Specific Transduction

(2009) Delphyne Descamps et al.   CURRENT GENE THERAPY

Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis

(2009) Changyong Li et al.   JOURNAL OF HEPATOLOGY

A micro cell culture analog (µCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs

(2009) Jong Hwan Sung et al.   LAB ON A CHIP

Synergistic drug–cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity

(2009) Benjamin D. Cosgrove et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Fusing Tissue Engineering and Systems Biology Toward Fulfilling Their Promise

(2008) Benjamin D. Cosgrove et al.   Cellular and Molecular Bioengineering

Mitochondrial dysfunction and delayed hepatotoxicity: another lesson from troglitazone

(2008) N. L. Julie et al.   DIABETOLOGIA

Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies

(2008) R. Josse et al.   DRUG METABOLISM AND DISPOSITION

Differentiation and Transplantation of Human Embryonic Stem Cell–Derived Hepatocytes

(2008) Hesham Basma et al.   GASTROENTEROLOGY

Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors

(2008) D M Appledorn et al.   GENE THERAPY

Up-Regulation of Drug-Metabolizing Enzyme Genes in Layered Co-Culture of a Human Liver Cell Line and Endothelial Cells

(2008) Maki Ohno et al.   TISSUE ENGINEERING PART A

Mature Human Hepatocytes from Ex Vivo Differentiation of Alginate-Encapsulated Hepatoblasts

(2008) Nancy Cheng et al.   TISSUE ENGINEERING PART A

Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury

(2008) Jinghai J. Xu et al.   TOXICOLOGICAL SCIENCES

The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity

(2007) Kjetil Elvevold et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Idiosyncratic Drug Reactions: Past, Present, and Future

(2007) Jack Uetrecht   CHEMICAL RESEARCH IN TOXICOLOGY