- Home
- Publications
- Publication Search
- Publication Details
Title
Road to stemness in hepatocellular carcinoma
Authors
Keywords
-
Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 23, Issue 37, Pages 6750-6776
Publisher
Baishideng Publishing Group Inc.
Online
2017-09-28
DOI
10.3748/wjg.v23.i37.6750
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Epigenetics in cancer stem cells
- (2017) Tan Boon Toh et al. Molecular Cancer
- Metabolic zonation of the liver: The oxygen gradient revisited
- (2017) Thomas Kietzmann Redox Biology
- Long Non-Coding RNAs: Key Regulators of Epithelial-Mesenchymal Transition, Tumour Drug Resistance and Cancer Stem Cells
- (2017) Richard Heery et al. Cancers
- A label-retaining but unipotent cell population resides in biliary compartment of mammalian liver
- (2017) Janeli Viil et al. Scientific Reports
- Synergistic effects of CD44 and TGF-β1 through AKT/GSK-3β/β-catenin signaling during epithelial-mesenchymal transition in liver cancer cells
- (2016) Na Ri Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The hypoxic microenvironment: A determinant of cancer stem cell evolution
- (2016) Amancio Carnero et al. BIOESSAYS
- Multi-organ Mapping of Cancer Risk
- (2016) Liqin Zhu et al. CELL
- Lineage tracing reveals conversion of liver sinusoidal endothelial cells into hepatocytes
- (2016) Zhaoli Tan et al. DEVELOPMENT GROWTH & DIFFERENTIATION
- The plastic cellular states of liver cells: Are EpCAM and Lgr5 fit for purpose?
- (2016) Meritxell Huch et al. HEPATOLOGY
- Stem/progenitor cells in liver regeneration
- (2016) Tohru Itoh HEPATOLOGY
- Genetic lineage tracing analysis of the cell of origin of hepatotoxin-induced liver tumors in mice
- (2016) Soona Shin et al. HEPATOLOGY
- The potential role of liver stem cells in initiation of primary liver cancer
- (2016) Xiao-Song Zhi et al. Hepatology International
- Constitutive expression of Wnt/β-catenin target genes promotes proliferation and invasion of liver cancer stem cells
- (2016) WEI CHEN et al. Molecular Medicine Reports
- Stem cells versus plasticity in liver and pancreas regeneration
- (2016) Janel L. Kopp et al. NATURE CELL BIOLOGY
- Side population in hepatocellular carcinoma HCCLM3 cells is enriched with stem-like cancer cells
- (2016) ZHE GUO et al. Oncology Letters
- Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
- (2016) Wenjuan Pu et al. Nature Communications
- Induced cancer stem cells generated by radiochemotherapy and their therapeutic implications
- (2016) Xiewan Chen et al. Oncotarget
- Hepatocellular Carcinoma-propagating Cells are Detectable by Side Population Analysis and Possess an Expression Profile Reflective of a Primitive Origin
- (2016) Honghai Xia et al. Scientific Reports
- An active IGF-1R-AKT signaling imparts functional heterogeneity in ovarian CSC population
- (2016) Ram K. Singh et al. Scientific Reports
- Targeting Cancer Stem Cells: Promises and Challenges
- (2015) Jan Dominik Kuhlmann et al. Anti-Cancer Agents in Medicinal Chemistry
- Identification of a unique hepatocellular carcinoma line, Li-7, with CD13(+) cancer stem cells hierarchy and population change upon its differentiation during culture and effects of sorafenib
- (2015) Takeshi Yamada et al. BMC CANCER
- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Cell-of-Origin of Cancer versus Cancer Stem Cells: Assays and Interpretations
- (2015) K. Rycaj et al. CANCER RESEARCH
- Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer
- (2015) Joan Font-Burgada et al. CELL
- UTX inhibits EMT-induced breast CSC properties by epigenetic repression of EMT genes in cooperation with LSD1 and HDAC1
- (2015) H.-J. Choi et al. EMBO REPORTS
- Ablation of Foxl1-Cre–Labeled Hepatic Progenitor Cells and Their Descendants Impairs Recovery of Mice From Liver Injury
- (2015) Soona Shin et al. GASTROENTEROLOGY
- Adaptive remodeling of the biliary architecture underlies liver homeostasis
- (2015) Kota Kaneko et al. HEPATOLOGY
- The hepatic, biliary, and pancreatic network of stem/progenitor cell niches in humans: A new reference frame for disease and regeneration
- (2015) Giacomo Lanzoni et al. HEPATOLOGY
- Lineage fate of ductular reactions in liver injury and carcinogenesis
- (2015) Simone Jörs et al. JOURNAL OF CLINICAL INVESTIGATION
- Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment
- (2015) Xueru Mu et al. JOURNAL OF CLINICAL INVESTIGATION
- Differential Sensitivities of Fast- and Slow-Cycling Cancer Cells to Inosine Monophosphate Dehydrogenase 2 Inhibition by Mycophenolic Acid
- (2015) Kan Chen et al. MOLECULAR MEDICINE
- Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver
- (2015) Bruce Wang et al. NATURE
- Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
- (2015) Devon A. Lawson et al. NATURE
- Hepatic progenitor cells of biliary origin with liver repopulation capacity
- (2015) Wei-Yu Lu et al. NATURE CELL BIOLOGY
- Curcumin induces glioma stem-like cell formation
- (2015) Lei Shi et al. NEUROREPORT
- Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrin–NF-κB–HIF-1α pathway
- (2015) Lei Cao et al. Oncotarget
- G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinoma
- (2015) Shuli Liu et al. Oncotarget
- Cisplatin Induces Bmi-1 and Enhances the Stem Cell Fraction in Head and Neck Cancer
- (2015) Carolina Nör et al. NEOPLASIA
- ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development
- (2014) Hayato Nakagawa et al. CANCER CELL
- Hippo Pathway Activity Influences Liver Cell Fate
- (2014) Dean Yimlamai et al. CELL
- Adult Hepatocytes Are Generated by Self-Duplication Rather than Stem Cell Differentiation
- (2014) Kilangsungla Yanger et al. Cell Stem Cell
- Stem/Progenitor Cells in Liver Development, Homeostasis, Regeneration, and Reprogramming
- (2014) Atsushi Miyajima et al. Cell Stem Cell
- Bipotential Adult Liver Progenitors Are Derived from Chronically Injured Mature Hepatocytes
- (2014) Branden D. Tarlow et al. Cell Stem Cell
- Clonal tracing of Sox9+liver progenitors in mouse oval cell injury
- (2014) Branden D. Tarlow et al. HEPATOLOGY
- The biliary epithelium gives rise to liver progenitor cells
- (2014) Daniel Rodrigo-Torres et al. HEPATOLOGY
- The plastic liver: differentiated cells, stem cells, every cell?
- (2014) Christopher J. Hindley et al. JOURNAL OF CLINICAL INVESTIGATION
- Hepatic stellate cells contribute to progenitor cells and liver regeneration
- (2014) Claus Kordes et al. JOURNAL OF CLINICAL INVESTIGATION
- A preventable cancer
- (2014) Lucas Laursen NATURE
- ALDH1A1 Maintains Ovarian Cancer Stem Cell-Like Properties by Altered Regulation of Cell Cycle Checkpoint and DNA Repair Network Signaling
- (2014) Erhong Meng et al. PLoS One
- Prominin-1 (CD133) Defines Both Stem and Non-Stem Cell Populations in CNS Development and Gliomas
- (2014) Karl Holmberg Olausson et al. PLoS One
- The CD133+CD44+ Precancerous Subpopulation of Oval Cells Is a Therapeutic Target for Hepatocellular Carcinoma
- (2014) Yun-Wen Zheng et al. STEM CELLS AND DEVELOPMENT
- Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury
- (2014) Johanna R. Schaub et al. Cell Reports
- Protein Kinases and Associated Pathways in Pluripotent State and Lineage Differentiation
- (2014) Melina Shoni et al. Current Stem Cell Research & Therapy
- Molecular Biology of Liver Cancer Stem Cells
- (2014) Naoki Oishi et al. Liver Cancer
- Relevant markers of cancer stem cells indicate a poor prognosis in hepatocellular carcinoma patients
- (2013) Yu-Cheng Ma et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Modeling Pathogenesis of Primary Liver Cancer in Lineage-Specific Mouse Cell Types
- (2013) Ágnes Holczbauer et al. GASTROENTEROLOGY
- Utility of Osteopontin in Lineage Tracing Experiments
- (2013) Jason Coombes et al. GASTROENTEROLOGY
- Links Between Hepatic Fibrosis, Ductular Reaction, and Progenitor Cell Expansion
- (2013) Michael J. Williams et al. GASTROENTEROLOGY
- Robust cellular reprogramming occurs spontaneously during liver regeneration
- (2013) K. Yanger et al. GENES & DEVELOPMENT
- Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy
- (2013) M Swiderska-Syn et al. GUT
- Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis
- (2013) Oriol Morales-Ibanez et al. HEPATOLOGY
- Receptor for advanced glycation endproducts (RAGE) is a key regulator of oval cell activation and inflammation-associated liver carcinogenesis in mice
- (2013) Tobias Pusterla et al. HEPATOLOGY
- Liver regeneration by stem/progenitor cells
- (2013) Tohru Itoh et al. HEPATOLOGY
- Smoothened is a master regulator of adult liver repair
- (2013) Gregory A. Michelotti et al. JOURNAL OF CLINICAL INVESTIGATION
- Cancer stem cells in the development of liver cancer
- (2013) Taro Yamashita et al. JOURNAL OF CLINICAL INVESTIGATION
- A murine model for non-alcoholic steatohepatitis showing evidence of association between diabetes and hepatocellular carcinoma
- (2013) Masato Fujii et al. Medical Molecular Morphology
- Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden
- (2013) Khalid Abubaker et al. Molecular Cancer
- Mouse models for liver cancer
- (2013) Latifa Bakiri et al. Molecular Oncology
- In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
- (2013) Meritxell Huch et al. NATURE
- Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs
- (2013) Neil C Henderson et al. NATURE MEDICINE
- Generation of Breast Cancer Stem Cells by Steroid Hormones in Irradiated Human Mammary Cell Lines
- (2013) Guillaume Vares et al. PLoS One
- Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
- (2013) A. Sottoriva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of the sonic hedgehog signaling pathway occurs in the CD133 positive cells of mouse liver cancer Hepa 1–6 cells
- (2013) Wen-Juei Jeng et al. OncoTargets and Therapy
- Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology
- (2013) Ingmar Mederacke et al. Nature Communications
- Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4
- (2012) Dianne H. Dapito et al. CANCER CELL
- Liver tumor-initiating cells as a therapeutic target for hepatocellular carcinoma
- (2012) Terence Kin Wah Lee et al. CANCER LETTERS
- CD44s Regulates the TGF- -Mediated Mesenchymal Phenotype and Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma
- (2012) K. Mima et al. CANCER RESEARCH
- Induction of cancer cell stemness by chemotherapy
- (2012) Xingwang Hu et al. CELL CYCLE
- Implication of hepatic stem cells in functional liver repopulation
- (2012) Bruno Christ et al. CYTOMETRY PART A
- Expression features of SOX9 associate with tumor progression and poor prognosis of hepatocellular carcinoma
- (2012) Xiaodong Guo et al. Diagnostic Pathology
- Liver Progenitor Cells Yield Functional Hepatocytes in Response to Chronic Liver Injury in Mice
- (2012) Regina Español–Suñer et al. GASTROENTEROLOGY
- Hepatic progenitor cells activation, fibrosis, and adipokines production in pediatric nonalcoholic fatty liver disease
- (2012) Valerio Nobili et al. HEPATOLOGY
- Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis
- (2012) Pau Sancho-Bru et al. HEPATOLOGY
- Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy
- (2012) Geeta Mehta et al. JOURNAL OF CONTROLLED RELEASE
- Aberrant microRNAs expression in CD133+/CD326+ human lung adenocarcinoma initiating cells from A549
- (2012) Sheng Lin et al. MOLECULES AND CELLS
- The biliary tree—a reservoir of multipotent stem cells
- (2012) Vincenzo Cardinale et al. Nature Reviews Gastroenterology & Hepatology
- Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice
- (2012) Rachel B. Reinert et al. PLoS One
- Ionizing Radiation Induces Stemness in Cancer Cells
- (2012) Laura Ghisolfi et al. PLoS One
- Clinical Implications of Cancer Stem Cell Biology in Hepatocellular Carcinoma
- (2012) Junfang Ji et al. SEMINARS IN ONCOLOGY
- Non-small cell lung cancer stem/progenitor cells are enriched in multiple distinct phenotypic subpopulations and exhibit plasticity
- (2012) S Akunuru et al. Cell Death & Disease
- Microenvironmental Regulation of Cancer Stem Cell Phenotypes
- (2012) Daniela F. Quail et al. Current Stem Cell Research & Therapy
- Technology update for the sorting and identification of breast cancer stem cells
- (2012) Jian Chen et al. Chinese Journal of Cancer
- Prediction of Posthepatectomy Recurrence of Hepatocellular Carcinoma by Circulating Cancer Stem Cells
- (2011) Sheung Tat Fan et al. ANNALS OF SURGERY
- Increased CD13 Expression Reduces Reactive Oxygen Species, Promoting Survival of Liver Cancer Stem Cells via an Epithelial–Mesenchymal Transition-like Phenomenon
- (2011) Ho Min Kim et al. ANNALS OF SURGICAL ONCOLOGY
- CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth
- (2011) Takatsugu Ishimoto et al. CANCER CELL
- Hepatic oval cell lines generate hepatocellular carcinoma following transfection with HBx gene and treatment with aflatoxin B1 in vivo
- (2011) Chang-Hai Li et al. CANCER LETTERS
- CD24+ Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation
- (2011) Terence Kin Wah Lee et al. Cell Stem Cell
- Eyes Wide Open: A Critical Review of Sphere-Formation as an Assay for Stem Cells
- (2011) Erika Pastrana et al. Cell Stem Cell
- Embryonic Ductal Plate Cells Give Rise to Cholangiocytes, Periportal Hepatocytes, and Adult Liver Progenitor Cells
- (2011) Rodolphe Carpentier et al. GASTROENTEROLOGY
- Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential
- (2011) S. Shin et al. GENES & DEVELOPMENT
- Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice
- (2011) C. Dorrell et al. GENES & DEVELOPMENT
- Successful isolation of liver progenitor cells by aldehyde dehydrogenase activity in naïve mice
- (2011) Laurent Dollé et al. HEPATOLOGY
- CD133+ liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling
- (2011) Kwan Ho Tang et al. HEPATOLOGY
- microRNA-150 inhibits human CD133-positive liver cancer stem cells through negative regulation of the transcription factor c-Myb
- (2011) Tao Zhang INTERNATIONAL JOURNAL OF ONCOLOGY
- Epithelial Cell Adhesion Molecule (EpCAM) Complex Proteins Promote Transcription Factor-mediated Pluripotency Reprogramming
- (2011) Hsiang-Po Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cells of origin in cancer
- (2011) Jane E. Visvader NATURE
- Osteopontin, intrinsic tissue regulator of intractable inflammatory diseases
- (2011) Toshimitsu Uede PATHOLOGY INTERNATIONAL
- ALDH Activity Selectively Defines an Enhanced Tumor-Initiating Cell Population Relative to CD133 Expression in Human Pancreatic Adenocarcinoma
- (2011) Michael P. Kim et al. PLoS One
- Evidence of Distinct Tumour-Propagating Cell Populations with Different Properties in Primary Human Hepatocellular Carcinoma
- (2011) Federico Colombo et al. PLoS One
- Epigenetic Modulation of miR-122 Facilitates Human Embryonic Stem Cell Self-Renewal and Hepatocellular Carcinoma Proliferation
- (2011) Christine J. Jung et al. PLoS One
- Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular Mechanisms
- (2011) Brahma N. Singh et al. PLoS One
- CD24-Positive Cells from Normal Adult Mouse Liver Are Hepatocyte Progenitor Cells
- (2011) Qiong Qiu et al. STEM CELLS AND DEVELOPMENT
- Cancer stem cells and hepatocellular carcinoma
- (2010) Zhixing Yao et al. CANCER BIOLOGY & THERAPY
- Clinicopathological Characteristics of 20 Cases of Hepatocellular Carcinoma with Bile Duct Tumor Thrombi
- (2010) Xian-huan Yu et al. DIGESTIVE DISEASES AND SCIENCES
- Pancreatic Cancer Cells Resistant to Chemoradiotherapy Rich in “Stem-Cell-Like” Tumor Cells
- (2010) Zhiyong Du et al. DIGESTIVE DISEASES AND SCIENCES
- Epigenetic gene silencing in the Wnt pathway in breast cancer
- (2010) George J. Klarmann et al. Epigenetics
- Epithelial cell adhesion molecule (EpCAM) marks hepatocytes newly derived from stem/progenitor cells in humans
- (2010) So-Mi Yoon et al. HEPATOLOGY
- CD13 is a therapeutic target in human liver cancer stem cells
- (2010) Naotsugu Haraguchi et al. JOURNAL OF CLINICAL INVESTIGATION
- Genetic variegation of clonal architecture and propagating cells in leukaemia
- (2010) Kristina Anderson et al. NATURE
- Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
- (2010) Louis Vermeulen et al. NATURE CELL BIOLOGY
- Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
- (2010) Kenichiro Furuyama et al. NATURE GENETICS
- The Cancer Stem Cell Hypothesis
- (2010) Maryam Rahman et al. NEUROSURGERY
- Coexistence of Quiescent and Active Adult Stem Cells in Mammals
- (2010) L. Li et al. SCIENCE
- Beta-catenin signaling, liver regeneration and hepatocellular cancer: Sorting the good from the bad
- (2010) Kari Nichole Nejak-Bowen et al. SEMINARS IN CANCER BIOLOGY
- Molecular Classification and Novel Targets in Hepatocellular Carcinoma: Recent Advancements
- (2010) Yujin Hoshida et al. SEMINARS IN LIVER DISEASE
- An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation
- (2009) Dimitrios Iliopoulos et al. CELL
- Cancer stem/progenitor cells are highly enriched in CD133+CD44+population in hepatocellular carcinoma
- (2009) Zheng Zhu et al. INTERNATIONAL JOURNAL OF CANCER
- Significance of CD90+ Cancer Stem Cells in Human Liver Cancer
- (2008) Zhen Fan Yang et al. CANCER CELL
- Wnt/ -Catenin Signaling Contributes to Activation of Normal and Tumorigenic Liver Progenitor Cells
- (2008) W. Yang et al. CANCER RESEARCH
- Cancer stem cells: never Wnt away from the niche
- (2008) Ilaria Malanchi et al. CURRENT OPINION IN ONCOLOGY
- Foxl1 is a marker of bipotential hepatic progenitor cells in mice
- (2008) Sara D. Sackett et al. HEPATOLOGY
- Experimental models of hepatocellular carcinoma
- (2008) Philippa Newell et al. JOURNAL OF HEPATOLOGY
- Stem cells in liver regeneration, fibrosis and cancer: the good, the bad and the ugly
- (2008) MR Alison et al. JOURNAL OF PATHOLOGY
- Expression of specific hepatocyte and cholangiocyte transcription factors in human liver disease and embryonic development
- (2008) Pallavi B Limaye et al. LABORATORY INVESTIGATION
- Aldehyde Dehydrogenase Discriminates the CD133 Liver Cancer Stem Cell Populations
- (2008) S. Ma et al. MOLECULAR CANCER RESEARCH
- Efficient tumour formation by single human melanoma cells
- (2008) Elsa Quintana et al. NATURE
- Progenitor/stem cells give rise to liver cancer due to aberrant TGF- and IL-6 signaling
- (2008) Y. Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Generation and Regeneration of Cells of the Liver and Pancreas
- (2008) K. S. Zaret et al. SCIENCE
- Fate-Mapping Evidence That Hepatic Stellate Cells Are Epithelial Progenitors in Adult Mouse Livers
- (2008) Liu Yang et al. STEM CELLS
- Stem cells, cell transplantation and liver repopulation
- (2007) Michael Oertel et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now