Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model

New targets for rapid antidepressant action

(2017) Rodrigo Machado-Vieira et al.   PROGRESS IN NEUROBIOLOGY

In-depth behavioral characterization of the corticosterone mouse model and the critical involvement of housing conditions

(2016) Thomas Demuyser et al.   PHYSIOLOGY & BEHAVIOR

Antioxidant treatment ameliorates experimental diabetes-induced depressive-like behaviour and reduces oxidative stress in brain and pancreas

(2015) Gislaine Z. Réus et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Hippocampal-Dependent Antidepressant Action of the H3Receptor Antagonist Clobenpropit in a Rat Model of Depression

(2015) Teresa Femenía et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed

(2015) Joeri Van Liefferinge et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Main path and byways: non-vesicular glutamate release by system xc−as an important modifier of glutamatergic neurotransmission

(2015) Ann Massie et al.   JOURNAL OF NEUROCHEMISTRY

Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review

(2015) Deepmala et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision

(2015) Eduard Bentea et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The Efficacy of AdjunctiveN-Acetylcysteine in Major Depressive Disorder

(2014) Michael Berk et al.   JOURNAL OF CLINICAL PSYCHIATRY

Glutamate transporter 1-mediated antidepressant-like effect in a rat model of chronic unpredictable stress

(2014) Jian-xin Chen et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders

(2014) Matthew P. Parsons et al.   NEURON

Behavioral assessment of acute inhibition of system xc - in rats

(2014) Victoria Lutgen et al.   PSYCHOPHARMACOLOGY

Postmortem Brain: An Underutilized Substrate for Studying Severe Mental Illness

(2013) Robert E McCullumsmith et al.   NEUROPSYCHOPHARMACOLOGY

Using the rat forced swim test to assess antidepressant-like activity in rodents

(2012) David A Slattery et al.   Nature Protocols

Synergist effects of n-acetylcysteine and deferoxamine treatment on behavioral and oxidative parameters induced by chronic mild stress in rats

(2012) Camila O. Arent et al.   NEUROCHEMISTRY INTERNATIONAL

Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice

(2012) Yukio Ago et al.   NEUROPHARMACOLOGY

N-acetylcysteine possesses antidepressant-like activity through reduction of oxidative stress: Behavioral and biochemical analyses in rats

(2012) Irena Smaga et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Loss of System xFormula Does Not Induce Oxidative Stress But Decreases Extracellular Glutamate in Hippocampus and Influences Spatial Working Memory and Limbic Seizure Susceptibility

(2011) D. De Bundel et al.   JOURNAL OF NEUROSCIENCE

The cystine–glutamate transporter enhancer N-acetyl-l-cysteine attenuates cocaine-induced changes in striatal dopamine but not self-administration in squirrel monkeys

(2011) Rayna M. Bauzo et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Magnetic Resonance Spectroscopy Studies of Glutamate-Related Abnormalities in Mood Disorders

(2010) Cagri Yüksel et al.   BIOLOGICAL PSYCHIATRY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dopaminergic neurons of system xc−-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity

(2010) Ann Massie et al.   FASEB JOURNAL

Reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 in learned helpless rats, an animal model of depression

(2009) M. Zink et al.   NEUROPHARMACOLOGY

N-Acetyl Cysteine as a Glutathione Precursor for Schizophrenia—A Double-Blind, Randomized, Placebo-Controlled Trial

(2008) Michael Berk et al.   BIOLOGICAL PSYCHIATRY

Time-dependent changes in striatal xCT protein expression in hemi-Parkinson rats

(2008) Ann Massie et al.   NEUROREPORT