Incorporating DNA Methyltransferase Inhibitors (DNMTis) in the Treatment of Genitourinary Malignancies: A Systematic Review

DNA methylation signature for the assessment of metastatic risk in primary renal cell cancer.

(2017) Inga Peters et al.   JOURNAL OF CLINICAL ONCOLOGY

Long non-coding RNA DBCCR1-003 regulate the expression of DBCCR1 via DNMT1 in bladder cancer

(2016) Defeng Qi et al.   Cancer Cell International

DNA Methylation Signature Reveals Cell Ontogeny of Renal Cell Carcinomas

(2016) G. G. Malouf et al.   CLINICAL CANCER RESEARCH

Epigenetic Targeting of Platinum Resistant Testicular Cancer

(2016) Daniel Sonnenburg et al.   CURRENT CANCER DRUG TARGETS

Epigenetic modifiers in immunotherapy: a focus on checkpoint inhibitors

(2016) Manuela Terranova-Barberio et al.   Immunotherapy

Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1

(2016) Tae-Dong Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Long Terminal Repeats: From Parasitic Elements to Building Blocks of the Transcriptional Regulatory Repertoire

(2016) Peter J. Thompson et al.   MOLECULAR CELL

Epigenome-based personalized medicine in human cancer

(2016) Wenji Yan et al.   Epigenomics

Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine

(2016) Costantine Albany et al.   Oncotarget

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts

(2015) David Roulois et al.   CELL

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

(2015) Katherine B. Chiappinelli et al.   CELL

Phase I/II Study of Azacitidine, Docetaxel, and Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Therapy

(2015) Rakesh Singal et al.   Clinical Genitourinary Cancer

Role of DNA methylation in renal cell carcinoma

(2015) Niraj Shenoy et al.   Journal of Hematology & Oncology

5-Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

(2015) XIAORONG WANG et al.   ONCOLOGY REPORTS

Epigenetic synergy between decitabine and platinum derivatives

(2015) Taichun Qin et al.   Clinical Epigenetics

Genome-wide methylation and transcriptome analysis in penile carcinoma: uncovering new molecular markers

(2015) Hellen Kuasne et al.   Clinical Epigenetics

Decitabine Enhances Lymphocyte Migration and Function and Synergizes with CTLA-4 Blockade in a Murine Ovarian Cancer Model

(2015) L. Wang et al.   Cancer Immunology Research

Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA-methyltransferase inhibitors

(2014) C Arimany-Nardi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Epigenetics Markers of Metastasis and HPV-Induced Tumorigenesis in Penile Cancer

(2014) A. Feber et al.   CLINICAL CANCER RESEARCH

The Novel, Small-Molecule DNA Methylation Inhibitor SGI-110 as an Ovarian Cancer Chemosensitizer

(2014) F. Fang et al.   CLINICAL CANCER RESEARCH

The evidence for functional non-CpG methylation in mammalian cells

(2014) Vibha Patil et al.   Epigenetics

DNA methylome profiling beyond promoters - taking an epigenetic snapshot of the breast tumor microenvironment

(2014) Jana Jeschke et al.   FEBS Journal

An Epigenetic Screen Unmasks Metallothioneins as Putative Contributors to Renal Cell Carcinogenesis

(2014) Imad Alkamal et al.   UROLOGIA INTERNATIONALIS

Promoter hypermethylation of tumor suppressor genes correlates with tumor grade and invasiveness in patients with urothelial bladder cancer

(2014) Shumaila M Bilgrami et al.   SpringerPlus

Alterations of DNA methylome in human bladder cancer

(2013) Ahmad Besaratinia et al.   Epigenetics

Zebularine partially reverses GST methylation in prostate cancer cells and restores sensitivity to the DNA minor groove binder brostallicin

(2013) Maria Antonietta Sabatino et al.   Epigenetics

Epigenetic Mechanisms in Penile Carcinoma

(2013) Hellen Kuasne et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360)

(2013) Godefridus J. Peters et al.   INVESTIGATIONAL NEW DRUGS

Nucleosome Remodeling and Epigenetics

(2013) P. B. Becker et al.   Cold Spring Harbor Perspectives in Biology

Endogenous retroviruses: acquisition, amplification and taming of genome invaders

(2013) Marie Dewannieux et al.   Current Opinion in Virology

Methylation profiling and evaluation of demethylating therapy in renal cell carcinoma

(2013) Christopher J Ricketts et al.   Clinical Epigenetics

3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models

(2013) Arkadiusz Gertych et al.   BMC Pharmacology & Toxicology

Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells

(2012) Hsing-Chen Tsai et al.   CANCER CELL

Immunomodulatory activity of SGI-110, a 5-aza-2′-deoxycytidine-containing demethylating dinucleotide

(2012) Sandra Coral et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Epigenetic Resensitization to Platinum in Ovarian Cancer

(2012) D. Matei et al.   CANCER RESEARCH

Fluorocyclopentenyl-cytosine with Broad Spectrum and Potent Antitumor Activity

(2012) Won Jun Choi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Acute Hypersensitivity of Pluripotent Testicular Cancer-Derived Embryonal Carcinoma to Low-Dose 5-Aza Deoxycytidine Is Associated with Global DNA Damage-Associated p53 Activation, Anti-Pluripotency and DNA Demethylation

(2012) Bijesh K. Biswal et al.   PLoS One

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Polycomb group genes are targets of aberrant DNA methylation in renal cell carcinoma

(2011) Michele Avissar-Whiting et al.   Epigenetics

DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter

(2011) Han Han et al.   HUMAN MOLECULAR GENETICS

Transcriptional Repressive H3K9 and H3K27 Methylations Contribute to DNMT1-Mediated DNA Methylation Recovery

(2011) Chun-Ming Wong et al.   PLoS One

GSTP1 DNA Methylation and Expression Status Is Indicative of 5-aza-2′-Deoxycytidine Efficacy in Human Prostate Cancer Cells

(2011) Karen Chiam et al.   PLoS One

Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types

(2011) Michael J. Ziller et al.   PLoS Genetics

Long-term Stability of Demethylation after Transient Exposure to 5-Aza-2'-Deoxycytidine Correlates with Sustained RNA Polymerase II Occupancy

(2010) J. D. Kagey et al.   MOLECULAR CANCER RESEARCH

S110, a 5-Aza-2'-Deoxycytidine-Containing Dinucleotide, Is an Effective DNA Methylation Inhibitor In vivo and Can Reduce Tumor Growth

(2010) J. C. Chuang et al.   MOLECULAR CANCER THERAPEUTICS

Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma

(2010) M R Morris et al.   ONCOGENE

High DNA Methyltransferase 3B Expression Mediates 5-Aza-Deoxycytidine Hypersensitivity in Testicular Germ Cell Tumors

(2009) M. J. Beyrouthy et al.   CANCER RESEARCH

A Phase I Dose-Finding Study of 5-Azacytidine in Combination with Sodium Phenylbutyrate in Patients with Refractory Solid Tumors

(2009) J. Lin et al.   CLINICAL CANCER RESEARCH

Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid Tumors

(2009) R. Plummer et al.   CLINICAL CANCER RESEARCH

Azacitidine improves antitumor effects of docetaxel and cisplatin in aggressive prostate cancer models

(2009) Claudio Festuccia et al.   ENDOCRINE-RELATED CANCER

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Azacitidine favorably modulates PSA kinetics correlating with plasma DNA LINE-1 hypomethylation in men with chemonaïve castration-resistant prostate cancer

(2009) Guru Sonpavde et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Phase I Study of Epigenetic Modulation with 5-Azacytidine and Valproic Acid in Patients with Advanced Cancers

(2008) F. Braiteh et al.   CLINICAL CANCER RESEARCH

Promoter analysis of epigenetically controlled genes in bladder cancer

(2008) Srinivas Veerla et al.   GENES CHROMOSOMES & CANCER

Global DNA hypomethylation in intratubular germ cell neoplasia and seminoma, but not in nonseminomatous male germ cell tumors

(2008) Georges J Netto et al.   MODERN PATHOLOGY