Development of a Perfusion Platform for Dynamic Cultivation of in vitro Skin Models

Atopic dermatitis and filaggrin

(2016) Beatriz Cabanillas et al.   CURRENT OPINION IN IMMUNOLOGY

Influence of Th2 Cytokines on the Cornified Envelope, Tight Junction Proteins, and β-Defensins in Filaggrin-Deficient Skin Equivalents

(2016) Stefan Hönzke et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment

(2015) Kerstin Reisinger et al.   TOXICOLOGY IN VITRO

Reduced filaggrin expression is accompanied by increasedStaphylococcus aureuscolonization of epidermal skin models

(2014) V. van Drongelen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Preclinical research: Make mouse studies work

(2014) Steve Perrin   NATURE

Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice

(2013) Marcel Leist et al.   ARCHIVES OF TOXICOLOGY

Combined LC/MS-platform for analysis of all major stratum corneum lipids, and the profiling of skin substitutes

(2013) Jeroen van Smeden et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Reconstructed skin models as emerging tools for drug absorption studies

(2013) Sarah Küchler et al.   Expert Opinion on Drug Metabolism & Toxicology

Role of fibroblasts in the pathogenesis of atopic dermatitis

(2013) Andreas Berroth et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The multifunctional role of filaggrin in allergic skin disease

(2013) Maeve A. McAleer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Filaggrin Deficiency Leads to Impaired Lipid Profile and Altered Acidification Pathways in a 3D Skin Construct

(2013) Kateřina Vávrová et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The potential of tissue engineering for developing alternatives to animal experiments: a systematic review

(2013) Rob B.M. de Vries et al.   Journal of Tissue Engineering and Regenerative Medicine

Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion

(2013) Beren Ataç et al.   LAB ON A CHIP

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanosensitive mechanisms in transcriptional regulation

(2012) Akiko Mammoto et al.   JOURNAL OF CELL SCIENCE

Full-Thickness Human Skin Models for Congenital Ichthyosis and Related Keratinization Disorders

(2011) Katja-Martina Eckl et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A Review of the Responses of Two- and Three-Dimensional Engineered Tissues to Electric Fields

(2011) Marie Hronik-Tupaj et al.   TISSUE ENGINEERING PART B-REVIEWS

Mechanical control of tissue and organ development

(2010) T. Mammoto et al.   DEVELOPMENT

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Dynamic culture conditions to generate silk-based tissue-engineered vascular grafts

(2009) Xiaohui Zhang et al.   BIOMATERIALS

The skin: an indispensable barrier

(2008) Ehrhardt Proksch et al.   EXPERIMENTAL DERMATOLOGY

Evaluation of beneficial and adverse effects of glucocorticoids on a newly developed full-thickness skin model

(2007) Nadja Nicole Zöller et al.   TOXICOLOGY IN VITRO