Molecular pathogenesis of viral hemorrhagic fever

Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages

(2017) Judith Olejnik et al.   JOURNAL OF VIROLOGY

Kinetic Analysis of Biomarkers in a Cohort of US Patients With Ebola Virus Disease

(2016) Anita K. McElroy et al.   CLINICAL INFECTIOUS DISEASES

Effects of Filovirus Interferon Antagonists on Responses of Human Monocyte-Derived Dendritic Cells to RNA Virus Infection

(2016) Benjamin C. Yen et al.   JOURNAL OF VIROLOGY

Yellow Fever Remains a Potential Threat to Public Health

(2016) Pedro F.C. Vasconcelos et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Vaccine and Wild-Type Strains of Yellow Fever Virus Engage Distinct Entry Mechanisms and Differentially Stimulate Antiviral Immune Responses

(2016) Maria Dolores Fernandez-Garcia et al.   mBio

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins

(2016) Megan R. Edwards et al.   Cell Reports

Assessing the Evidence Supporting Fruit Bats as the Primary Reservoirs for Ebola Viruses

(2015) Siv Aina J. Leendertz et al.   EcoHealth

Yellow fever

(2015) Thomas P. Monath et al.   JOURNAL OF CLINICAL VIROLOGY

Human Ebola virus infection results in substantial immune activation

(2015) Anita K. McElroy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant Marburg viruses containing mutations in the IID region of VP35 prevent inhibition of Host immune responses

(2015) César G. Albariño et al.   VIROLOGY

Experimental Inoculation of Egyptian Rousette Bats (Rousettus aegyptiacus) with Viruses of the Ebolavirus and Marburgvirus Genera

(2015) Megan Jones et al.   Viruses-Basel

The Z Proteins of Pathogenic but Not Nonpathogenic Arenaviruses Inhibit RIG-i-Like Receptor-Dependent Interferon Production

(2015) Junji Xing et al.   JOURNAL OF VIROLOGY

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1

(2014) Wei Xu et al.   Cell Host & Microbe

The Interferon Signaling Antagonist Function of Yellow Fever Virus NS5 Protein Is Activated by Type I Interferon

(2014) Maudry Laurent-Rolle et al.   Cell Host & Microbe

Functional CD8+ T Cell Responses in Lethal Ebola Virus Infection

(2014) S. B. Bradfute et al.   JOURNAL OF IMMUNOLOGY

Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses

(2014) Roosecelis Brasil Martines et al.   JOURNAL OF PATHOLOGY

The Exonuclease Domain of Lassa Virus Nucleoprotein Is Involved in Antigen-Presenting-Cell-Mediated NK Cell Responses

(2014) M. Russier et al.   JOURNAL OF VIROLOGY

Exonuclease Domain of the Lassa Virus Nucleoprotein Is Critical To Avoid RIG-I Signaling and To Inhibit the Innate Immune Response

(2014) S. Reynard et al.   JOURNAL OF VIROLOGY

Molecular Basis for Ebolavirus VP35 Suppression of Human Dendritic Cell Maturation

(2014) B. Yen et al.   JOURNAL OF VIROLOGY

Interferon-stimulated genes: roles in viral pathogenesis

(2014) John W Schoggins   Current Opinion in Virology

Pathophysiologic and Transcriptomic Analyses of Viscerotropic Yellow Fever in a Rhesus Macaque Model

(2014) Flora Engelmann et al.   PLoS Neglected Tropical Diseases

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA

(2013) Jens H. Kuhn et al.   ARCHIVES OF VIROLOGY

Mutual Antagonism between the Ebola Virus VP35 Protein and the RIG-I Activator PACT Determines Infection Outcome

(2013) Priya Luthra et al.   Cell Host & Microbe

Ebola Virus Exploits a Monocyte Differentiation Program To Promote Its Entry

(2013) O. Martinez et al.   JOURNAL OF VIROLOGY

The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

(2013) N. M. Lubaki et al.   JOURNAL OF VIROLOGY

Pathogenesis of the Viral Hemorrhagic Fevers

(2012) Slobodan Paessler et al.   Annual Review of Pathology-Mechanisms of Disease

Structural insights into RNA recognition and activation of RIG-I-like receptors

(2012) Daisy W Leung et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Basic Clinical and Laboratory Features of Filoviral Hemorrhagic Fever

(2011) Mark G. Kortepeter et al.   JOURNAL OF INFECTIOUS DISEASES

Pathogenesis of Marburg Hemorrhagic Fever in Cynomolgus Macaques

(2011) Lisa E. Hensley et al.   JOURNAL OF INFECTIOUS DISEASES

VP24 Is a Molecular Determinant of Ebola Virus Virulence in Guinea Pigs

(2011) Mathieu Mateo et al.   JOURNAL OF INFECTIOUS DISEASES

Host Response Dynamics Following Lethal Infection of Rhesus Macaques With Zaire ebolavirus

(2011) Hideki Ebihara et al.   JOURNAL OF INFECTIOUS DISEASES

Human Dendritic Cells Infected with the Nonpathogenic Mopeia Virus Induce Stronger T-Cell Responses than Those Infected with Lassa Virus

(2011) D. Pannetier et al.   JOURNAL OF VIROLOGY

Marburg Virus VP40 Antagonizes Interferon Signaling in a Species-Specific Manner

(2011) C. Valmas et al.   JOURNAL OF VIROLOGY

Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression

(2011) K. M. Hastie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenesis of lassa fever in cynomolgus macaques

(2011) Lisa E Hensley et al.   Virology Journal

Mutations Abrogating VP35 Interaction with Double-Stranded RNA Render Ebola Virus Avirulent in Guinea Pigs

(2010) K. C. Prins et al.   JOURNAL OF VIROLOGY

Are we any closer to combating Ebola infections?

(2010) Heinz Feldmann   LANCET

Cap binding and immune evasion revealed by Lassa nucleoprotein structure

(2010) Xiaoxuan Qi et al.   NATURE

Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35

(2010) Daisy W Leung et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human Fatal Zaire Ebola Virus Infection Is Associated with an Aberrant Innate Immunity and with Massive Lymphocyte Apoptosis

(2010) Nadia Wauquier et al.   PLoS Neglected Tropical Diseases

Steric Shielding of Surface Epitopes and Impaired Immune Recognition Induced by the Ebola Virus Glycoprotein

(2010) Joseph R. Francica et al.   PLoS Pathogens

Marburg Virus Evades Interferon Responses by a Mechanism Distinct from Ebola Virus

(2010) Charalampos Valmas et al.   PLoS Pathogens

The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide

(2009) H. Jin et al.   JOURNAL OF GENERAL VIROLOGY

Ebola Virus VP35 Antagonizes PKR Activity through Its C-Terminal Interferon Inhibitory Domain

(2009) M. Schumann et al.   JOURNAL OF VIROLOGY

Z Proteins of New World Arenaviruses Bind RIG-I and Interfere with Type I Interferon Induction

(2009) L. Fan et al.   JOURNAL OF VIROLOGY

Ebola Virus Protein VP35 Impairs the Function of Interferon Regulatory Factor-Activating Kinases IKK  and TBK-1

(2009) K. C. Prins et al.   JOURNAL OF VIROLOGY

Interaction between Ebola Virus Glycoprotein and Host Toll-Like Receptor 4 Leads to Induction of Proinflammatory Cytokines and SOCS1

(2009) A. Okumura et al.   JOURNAL OF VIROLOGY

De novo cholangiocarcinoma after liver transplantation in a pediatric patient

(2009) Nandini Channabasappa et al.   PEDIATRIC TRANSPLANTATION

Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein

(2009) Rachel L. Kaletsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification Machinery

(2009) Tsung-Hsien Chang et al.   PLoS Pathogens

Cell Adhesion Promotes Ebola Virus Envelope Glycoprotein-Mediated Binding and Infection

(2008) D. Dube et al.   JOURNAL OF VIROLOGY

Inhibition of IRF-3 Activation by VP35 Is Critical for the High Level of Virulence of Ebola Virus

(2008) A. L. Hartman et al.   JOURNAL OF VIROLOGY

Whole-Genome Expression Profiling Reveals That Inhibition of Host Innate Immune Response Pathways by Ebola Virus Can Be Reversed by a Single Amino Acid Change in the VP35 Protein

(2008) A. L. Hartman et al.   JOURNAL OF VIROLOGY

Treatment of yellow fever

(2007) Thomas P. Monath   ANTIVIRAL RESEARCH