Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35

Expression, purification, crystallization and preliminary X-ray studies of the Ebola VP35 interferon inhibitory domain

(2009) Daisy W. Leung et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5

(2009) Xiaojun Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

Solution Structures of Cytosolic RNA Sensor MDA5 and LGP2 C-terminal Domains

(2009) Kiyohiro Takahasi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNA

(2009) Xiaojun Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evasion of Interferon Responses by Ebola and Marburg Viruses

(2009) Christopher F. Basler et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Ebola Virus VP35 Antagonizes PKR Activity through Its C-Terminal Interferon Inhibitory Domain

(2009) M. Schumann et al.   JOURNAL OF VIROLOGY

Ebola Virus Protein VP35 Impairs the Function of Interferon Regulatory Factor-Activating Kinases IKK  and TBK-1

(2009) K. C. Prins et al.   JOURNAL OF VIROLOGY

The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA

(2009) Diana A. Pippig et al.   NUCLEIC ACIDS RESEARCH

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

(2009) A. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Ebola VP35 interferon inhibitory domain

(2009) D. W. Leung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIG-I activation inhibits ebolavirus replication

(2009) Christina F. Spiropoulou et al.   VIROLOGY

Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification Machinery

(2009) Tsung-Hsien Chang et al.   PLoS Pathogens

Approaching the RNA ligand for RIG-I?

(2008) Martin Schlee et al.   IMMUNOLOGICAL REVIEWS

Structure and Function of LGP2, a DEX(D/H) Helicase That Regulates the Innate Immunity Response

(2008) Ayaluru Murali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential recognition of double-stranded RNA by RIG-I–like receptors in antiviral immunity: Figure 1.

(2008) Takeshi Saito et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Filovirus-Unique Region of Ebola Virus Nucleoprotein Confers Aberrant Migration and Mediates Its Incorporation into Virions

(2008) W. Shi et al.   JOURNAL OF VIROLOGY

Inhibition of IRF-3 Activation by VP35 Is Critical for the High Level of Virulence of Ebola Virus

(2008) A. L. Hartman et al.   JOURNAL OF VIROLOGY

Whole-Genome Expression Profiling Reveals That Inhibition of Host Innate Immune Response Pathways by Ebola Virus Can Be Reversed by a Single Amino Acid Change in the VP35 Protein

(2008) A. L. Hartman et al.   JOURNAL OF VIROLOGY

Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

(2008) Matthias Habjan et al.   PLoS One

RIG-I and dsRNA-Induced IFNβ Activation

(2008) Stéphane Hausmann et al.   PLoS One