A dose-dependent plasma signature of the safety and immunogenicity of the rVSV-Ebola vaccine in Europe and Africa

Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

(2017) Ana Maria Henao-Restrepo et al.   LANCET

Chimpanzee Adenovirus Vector Ebola Vaccine

(2017) Julie E. Ledgerwood et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Recombinant Vesicular Stomatitis Virus Ebola Vaccine

(2017) Jason A. Regules et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute Changes in Striatal Microstructure Predict the Development of Interferon-Alpha Induced Fatigue

(2016) Nicholas G. Dowell et al.   BIOLOGICAL PSYCHIATRY

Safety and Immunogenicity of Novel Adenovirus Type 26– and Modified Vaccinia Ankara–Vectored Ebola Vaccines

(2016) Iain D. Milligan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Use of ChAd3-EBO-Z Ebola virus vaccine in Malian and US adults, and boosting of Malian adults with MVA-BN-Filo: a phase 1, single-blind, randomised trial, a phase 1b, open-label and double-blind, dose-escalation trial, and a nested, randomised, double-blind, placebo-controlled trial

(2016) Milagritos D Tapia et al.   LANCET INFECTIOUS DISEASES

Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a study

(2016) Olga De Santis et al.   LANCET INFECTIOUS DISEASES

Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events

(2016) Olga Sobolev et al.   NATURE IMMUNOLOGY

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe

(2016) Selidji T. Agnandji et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

(2016) Katie Ewer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood

(2016) Helder I. Nakaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Live virus vaccines based on a vesicular stomatitis virus (VSV) backbone: Standardized template with key considerations for a risk/benefit assessment

(2016) David K. Clarke et al.   VACCINE

Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures

(2015) Helder I. Nakaya et al.   IMMUNITY

Emergency Postexposure Vaccination With Vesicular Stomatitis Virus–Vectored Ebola Vaccine After Needlestick

(2015) Lilin Lai et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Loss of Interleukin 1 Receptor Antagonist Enhances Susceptibility to Ebola Virus Infection

(2015) Lindsay Hill-Batorski et al.   JOURNAL OF INFECTIOUS DISEASES

Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial

(2015) Hannah Kibuuka et al.   LANCET

Safety and immunogenicity of a novel recombinant adenovirus type-5 vector-based Ebola vaccine in healthy adults in China: preliminary report of a randomised, double-blind, placebo-controlled, phase 1 trial

(2015) Feng-Cai Zhu et al.   LANCET

Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

(2015) Ana Maria Henao-Restrepo et al.   LANCET

The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial

(2015) Angela Huttner et al.   LANCET INFECTIOUS DISEASES

VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain

(2015) A. Marzi et al.   SCIENCE

Ebola vaccine R&D: Filling the knowledge gaps

(2015) Donata Medaglini et al.   Science Translational Medicine

Focused human gene expression profiling using dual-color reverse transcriptase multiplex ligation-dependent probe amplification

(2015) Mariëlle C. Haks et al.   VACCINE

The Role of Cytokines and Chemokines in Filovirus Infection

(2015) Sandra Bixler et al.   Viruses-Basel

Oncolytic viruses: From bench to bedside with a focus on safety

(2015) Pascal RA Buijs et al.   Human Vaccines & Immunotherapeutics

Immune activation alters cellular and humoral responses to yellow fever 17D vaccine

(2014) Enoch Muyanja et al.   JOURNAL OF CLINICAL INVESTIGATION

Ebola Hemorrhagic Fever: Novel Biomarker Correlates of Clinical Outcome

(2014) A. K. McElroy et al.   JOURNAL OF INFECTIOUS DISEASES

Ebola Vaccine — An Urgent International Priority

(2014) Rupa Kanapathipillai et al.   NEW ENGLAND JOURNAL OF MEDICINE

Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability

(2014) Beatriz Escudero-Pérez et al.   PLoS Pathogens

Ebola Virus Exploits a Monocyte Differentiation Program To Promote Its Entry

(2013) O. Martinez et al.   JOURNAL OF VIROLOGY

Molecular signatures of antibody responses derived from a systems biology study of five human vaccines

(2013) Shuzhao Li et al.   NATURE IMMUNOLOGY

Learning from the Messengers: Innate Sensing of Viruses and Cytokine Regulation of Immunity — Clues for Treatments and Vaccines

(2013) Jesper Melchjorsen   Viruses-Basel

Cytokine and chemokine responses to Japanese encephalitis live attenuated vaccine in a human population

(2012) Jiu-Song Zhang et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Vesicular stomatitis virus as a flexible platform for oncolytic virotherapy against cancer

(2012) E. Hastie et al.   JOURNAL OF GENERAL VIROLOGY

Acute Reactogenicity after Intramuscular Immunization with Recombinant Vesicular Stomatitis Virus Is Linked to Production of IL-1β

(2012) Kathleen Athearn et al.   PLoS One

Identification of biomarkers for tuberculosis disease using a novel dual-color RT–MLPA assay

(2011) S A Joosten et al.   GENES AND IMMUNITY

Cytokine Signatures of Innate and Adaptive Immunity in 17DD Yellow Fever Vaccinated Children and Its Association With the Level of Neutralizing Antibody

(2011) M. Luiza-Silva et al.   JOURNAL OF INFECTIOUS DISEASES

Vesicular Stomatitis Virus–Based Ebola Vaccines With Improved Cross-Protective Efficacy

(2011) Andrea Marzi et al.   JOURNAL OF INFECTIOUS DISEASES

Pathways for Cytokine Secretion

(2010) Amanda C. Stanley et al.   PHYSIOLOGY

High Prevalence of Both Humoral and Cellular Immunity to Zaire ebolavirus among Rural Populations in Gabon

(2010) Pierre Becquart et al.   PLoS One

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Interaction between Ebola Virus Glycoprotein and Host Toll-Like Receptor 4 Leads to Induction of Proinflammatory Cytokines and SOCS1

(2009) A. Okumura et al.   JOURNAL OF VIROLOGY

Interleukin-6 acts in the fashion of a classical chemokine on monocytic cells by inducing integrin activation, cell adhesion, actin polymerization, chemotaxis, and transmigration

(2008) Thomas Clahsen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY