Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration
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Title
Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration
Authors
Keywords
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Journal
Science Translational Medicine
Volume 9, Issue 395, Pages eaaf1443
Publisher
American Association for the Advancement of Science (AAAS)
Online
2017-08-18
DOI
10.1126/scitranslmed.aaf1443
References
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Related references
Note: Only part of the references are listed.- Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels
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- Clinical and Genetic Factors Associated with Progression of Geographic Atrophy Lesions in Age-Related Macular Degeneration
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- (2013) Johanna M Seddon et al. NATURE GENETICS
- A functional variant in the CFI gene confers a high risk of age-related macular degeneration
- (2013) Johannes P H van de Ven et al. NATURE GENETICS
- Seven new loci associated with age-related macular degeneration
- (2013) Lars G Fritsche et al. NATURE GENETICS
- A PHASE IA DOSE-ESCALATION STUDY OF THE ANTI-FACTOR D MONOCLONAL ANTIBODY FRAGMENT FCFD4514S IN PATIENTS WITH GEOGRAPHIC ATROPHY
- (2013) Diana V. Do et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Square Root Transformation of Geographic Atrophy Area Measurements to Eliminate Dependence of Growth Rates on Baseline Lesion Measurements: A Reanalysis of Age-Related Eye Disease Study Report No. 26
- (2013) William J. Feuer et al. JAMA Ophthalmology
- Inhibiting Alternative Pathway Complement Activation by Targeting the Factor D Exosite
- (2012) Kenneth J. Katschke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Age-related macular degeneration
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- Genetic insights into age-related macular degeneration: Controversies addressing risk, causality, and therapeutics
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- (2010) T. D. Wu et al. BIOINFORMATICS
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- BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources
- (2009) Chunlei Wu et al. GENOME BIOLOGY
- Systemic Complement Activation in Age-Related Macular Degeneration
- (2008) Hendrik P. N. Scholl et al. PLoS One
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