Topology: a unique dimension in protein engineering

Lasso Peptide Benenodin-1 Is a Thermally Actuated [1]Rotaxane Switch

(2017) Chuhan Zong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A new genome-mining tool redefines the lasso peptide biosynthetic landscape

(2017) Jonathan I Tietz et al.   Nature Chemical Biology

Knotting and unknotting proteins in the chaperonin cage: Effects of the excluded volume

(2017) Szymon Niewieczerzal et al.   PLoS One

Braiding a molecular knot with eight crossings

(2017) Jonathan J. Danon et al.   SCIENCE

Giant molecules: where chemistry, physics, and bio-science meet

(2017) Guang-Zhong Yin et al.   Science China-Chemistry

Synthesis and stabilities of peptide-based [1]rotaxanes: molecular grafting onto lasso peptide scaffolds

(2017) Fumito Saito et al.   Chemical Science

Tuning SpyTag–SpyCatcher mutant pairs toward orthogonal reactivity encryption

(2017) Yajie Liu et al.   Chemical Science

From protein domains to molecular nanoparticles: what can giant molecules learn from proteins?

(2017) Wen-Bin Zhang et al.   Materials Horizons

Topology Engineering of Proteins in Vivo Using Genetically Encoded, Mechanically Interlocking SpyX Modules for Enhanced Stability

(2017) Dong Liu et al.   ACS Central Science

Probing the potential of CnaB-type domains for the design of tag/catcher systems

(2017) Marlene Pröschel et al.   PLoS One

Thermal Unthreading of the Lasso Peptides Astexin-2 and Astexin-3

(2016) Caitlin D. Allen et al.   ACS Chemical Biology

Cellular Synthesis of Protein Catenanes

(2016) Xiao-Wei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PROLink—Single Step Circularization and Purification Procedure for the Generation of an Improved Variant of Human Growth Hormone

(2016) Nicolas Rasche et al.   BIOCONJUGATE CHEMISTRY

Enhanced thermal stability of lichenase from Bacillus subtilis 168 by SpyTag/SpyCatcher-mediated spontaneous cyclization

(2016) Jindan Wang et al.   Biotechnology for Biofuels

Knot theory in modern chemistry

(2016) Kate E. Horner et al.   CHEMICAL SOCIETY REVIEWS

Natural supramolecular protein assemblies

(2016) Bas J. G. E. Pieters et al.   CHEMICAL SOCIETY REVIEWS

Recent Advances in the Synthesis and Functions of Reconfigurable Interlocked DNA Nanostructures

(2016) Chun-Hua Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembly of Catenanes from Lasso Peptides

(2016) Caitlin D. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Butelase-mediated cyclization and ligation of peptides and proteins

(2016) Giang K T Nguyen et al.   Nature Protocols

Mixed [2 : 6] hetero-arm star polymers based on Janus POSS with precisely defined arm distribution

(2016) Yu Shao et al.   Polymer Chemistry

Programmable polyproteams built using twin peptide superglues

(2016) Gianluca Veggiani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein self-assembly: technology and strategy

(2016) Linlu Zhao et al.   Science China-Chemistry

Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers

(2016) Shu J. Lam et al.   Nature Microbiology

SpyTag/SpyCatcher Cyclization Enhances the Thermostability of Firefly Luciferase

(2016) Meng Si et al.   PLoS One

Kinetic Controlled Tag-Catcher Interactions for Directed Covalent Protein Assembly

(2016) Lee Ling Tan et al.   PLoS One

In Search of Functional Advantages of Knots in Proteins

(2016) Pawel Dabrowski-Tumanski et al.   PLoS One

SpyRing interrogation: analyzing how enzyme resilience can be achieved with phytase and distinct cyclization chemistries

(2016) Christopher Schoene et al.   Scientific Reports

Complex lasso: new entangled motifs in proteins

(2016) Wanda Niemyska et al.   Scientific Reports

Lasso Peptides: An Intriguing Class of Bacterial Natural Products

(2015) Julian D. Hegemann et al.   ACCOUNTS OF CHEMICAL RESEARCH

Construction of Lasso Peptide Fusion Proteins

(2015) Chuhan Zong et al.   ACS Chemical Biology

Catenanes: Fifty Years of Molecular Links

(2015) Guzmán Gil-Ramírez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Artificial Molecular Machines

(2015) Sundus Erbas-Cakmak et al.   CHEMICAL REVIEWS

Secrets of a covalent interaction for biomaterials and biotechnology: SpyTag and SpyCatcher

(2015) Samuel C Reddington et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Prediction of the optimal set of contacts to fold the smallest knotted protein

(2015) P Dabrowski-Tumanski et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Molecular knots in biology and chemistry

(2015) Nicole C H Lim et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Butelase 1: A Versatile Ligase for Peptide and Protein Macrocyclization

(2015) Giang K. T. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Backbone circularization of Bacillus subtilis family 11 xylanase increases its thermostability and its resistance against aggregation

(2015) Max C. Waldhauer et al.   Molecular BioSystems

Methods for the directed evolution of proteins

(2015) Michael S. Packer et al.   NATURE REVIEWS GENETICS

Star polymers: Advances in biomedical applications

(2015) Wei Wu et al.   PROGRESS IN POLYMER SCIENCE

Switchable Reconfiguration of an Interlocked DNA Olympiadane Nanostructure

(2014) Chun-Hua Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

SpyTag/SpyCatcher Cyclization Confers Resilience to Boiling on a Mesophilic Enzyme

(2014) Christopher Schoene et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Peptide Macrocyclization Catalyzed by a Prolyl Oligopeptidase Involved in α-Amanitin Biosynthesis

(2014) Hong Luo et al.   CHEMISTRY & BIOLOGY

Mechanically Tightening a Protein Slipknot into a Trefoil Knot

(2014) Chengzhi He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis

(2014) Giang K T Nguyen et al.   Nature Chemical Biology

A Star of David catenane

(2014) David A. Leigh et al.   Nature Chemistry

KnotProt: a database of proteins with knots and slipknots

(2014) Michal Jamroz et al.   NUCLEIC ACIDS RESEARCH

SpyLigase peptide–peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture

(2014) Jacob O. Fierer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence that the catenane form of CS2 hydrolase is not an artefact

(2013) Mark B. van Eldijk et al.   CHEMICAL COMMUNICATIONS

What molecular assembly can learn from catalytic chemistry

(2013) Yu Wang et al.   CHEMICAL SOCIETY REVIEWS

The Two-step Biosynthesis of Cyclic Peptides from Linear Precursors in a Member of the Plant Family Caryophyllaceae Involves Cyclization by a Serine Protease-like Enzyme

(2013) Carla J. S. Barber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Analysis and Optimization of the Covalent Association between SpyCatcher and a Peptide Tag

(2013) Long Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Controlling Macromolecular Topology with Genetically Encoded SpyTag–SpyCatcher Chemistry

(2013) Wen-Bin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A pH-Sensitive Peptide-Containing Lasso Molecular Switch

(2013) Caroline Clavel et al.   MOLECULES

Lasso peptides: structure, function, biosynthesis, and engineering

(2012) Mikhail O. Maksimov et al.   NATURAL PRODUCT REPORTS

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

(2012) B. Zakeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conservation of complex knotting and slipknotting patterns in proteins

(2012) J. I. Sulkowska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tangled Up in Knots: Structures of Inactivated Forms of E. coli Class Ia Ribonucleotide Reductase

(2012) Christina M. Zimanyi et al.   STRUCTURE

Introducing Lasso Peptides as Molecular Scaffolds for Drug Design: Engineering of an Integrin Antagonist

(2011) Thomas A. Knappe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

AS-48 bacteriocin: close to perfection

(2011) Marina Sánchez-Hidalgo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Bioactive cystine knot proteins

(2011) Norelle L Daly et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Split-protein systems: beyond binary protein–protein interactions

(2011) Sujan S Shekhawat et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Sequence Diversity in the Lasso Peptide Framework: Discovery of Functional Microcin J25 Variants with Multiple Amino Acid Substitutions

(2011) Si Jia Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Knot formation in newly translated proteins is spontaneous and accelerated by chaperonins

(2011) Anna L Mallam et al.   Nature Chemical Biology

Sortase-catalyzed transformations that improve the properties of cytokines

(2011) M. W. Popp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circular proteins and mechanisms of cyclization

(2010) Brendon F. Conlan et al.   BIOPOLYMERS

Spontaneous Intermolecular Amide Bond Formation between Side Chains for Irreversible Peptide Targeting

(2010) Bijan Zakeri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Naturally occurring circular proteins: distribution, biosynthesis and evolution

(2010) Laura Cascales et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Miktoarm star polymers: advances in synthesis, self-assembly, and applications

(2010) Kunal Khanna et al.   Polymer Chemistry

Structure and folding of a designed knotted protein

(2010) N. P. King et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circular permutation: a different way to engineer enzyme structure and function

(2010) Ying Yu et al.   TRENDS IN BIOTECHNOLOGY

A Straight Path to Circular Proteins

(2009) John M. Antos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Using Marine Natural Products to Discover a Protease that Catalyzes Peptide Macrocyclization of Diverse Substrates

(2009) Jaeheon Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stretching topology

(2009) Michelle Francl   Nature Chemistry

Exploring protein fitness landscapes by directed evolution

(2009) Philip A. Romero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dodging the crisis of folding proteins with knots

(2009) J. I. Sulkowska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation and Structural Characterization of Capistruin, a Lasso Peptide Predicted from the Genome Sequence of Burkholderia thailandensis E264

(2008) Thomas A. Knappe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Research in Macromolecular Science: Challenges and Opportunities for the Next Decade

(2008) C. K. Ober et al.   MACROMOLECULES

Stabilizing effect of knots on proteins

(2008) J. I. Sulkowska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA