Lasso peptides: structure, function, biosynthesis, and engineering

Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171

(2012) Junji Inokoshi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Synthetic peptides derived from the sequence of a lasso peptide microcin J25 show antibacterial activity

(2012) Rania Soudy et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Sequence Determinants Governing the Topology and Biological Activity of a Lasso Peptide, Microcin J25

(2012) Rémi Ducasse et al.   CHEMBIOCHEM

Dissecting the Maturation Steps of the Lasso Peptide Microcin J25 in vitro

(2012) Kok-Phen Yan et al.   CHEMBIOCHEM

NMR as an Effective Tool for the Structure Determination of Lasso Peptides

(2012) Xiulan Xie et al.   CHEMBIOCHEM

Introducing Lasso Peptides as Molecular Scaffolds for Drug Design: Engineering of an Integrin Antagonist

(2011) Thomas A. Knappe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of a Single Polypeptide that Matures and Exports the Lasso Peptide Microcin J25

(2011) Si Jia Pan et al.   CHEMBIOCHEM

The role of a conserved threonine residue in the leader peptide of lasso peptide precursors

(2011) Si Jia Pan et al.   CHEMICAL COMMUNICATIONS

The Antibacterial Threaded-lasso Peptide Capistruin Inhibits Bacterial RNA Polymerase

(2011) Konstantin Kuznedelov et al.   JOURNAL OF MOLECULAR BIOLOGY

Sequence Diversity in the Lasso Peptide Framework: Discovery of Functional Microcin J25 Variants with Multiple Amino Acid Substitutions

(2011) Si Jia Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Topoisomer Differentiation of Molecular Knots by FTICR MS: Lessons from Class II Lasso Peptides

(2011) Séverine Zirah et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

A mass spectrometry–guided genome mining approach for natural product peptidogenomics

(2011) Roland D Kersten et al.   Nature Chemical Biology

An Experimental and Computational Investigation of Spontaneous Lasso Formation in Microcin J25

(2010) Andrew L. Ferguson et al.   BIOPHYSICAL JOURNAL

High-Resolution Crystal Structure of a Lasso Peptide

(2010) Herbert Nar et al.   ChemMedChem

Genome mining for ribosomally synthesized natural products

(2010) Juan E Velásquez et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Much of the Microcin J25 Leader Peptide is Dispensable

(2010) Wai Ling Cheung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computational design of the lasso peptide antibiotic microcin J25

(2010) S. J. Pan et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Lys17 in the ‘lasso’ peptide lariatin A is responsible for anti-mycobacterial activity

(2009) Masato Iwatsuki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Insights into the Biosynthesis and Stability of the Lasso Peptide Capistruin

(2009) Thomas A. Knappe et al.   CHEMISTRY & BIOLOGY

The glucagon receptor antagonist BI-32169 constitutes a new class of lasso peptides

(2009) Thomas A. Knappe et al.   FEBS LETTERS

The Ile13residue of microcin J25 is essential for recognition by the receptor FhuA, but not by the inner membrane transporter SbmA

(2009) Sergio B. Socias et al.   FEMS MICROBIOLOGY LETTERS

Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds

(2009) John A. McIntosh et al.   NATURAL PRODUCT REPORTS

Engineered gene clusters for the production of the antimicrobial peptide microcin J25

(2009) Si Jia Pan et al.   PROTEIN EXPRESSION AND PURIFICATION

Ribosomal Synthesis of Tricyclic Depsipeptides in Bloom-Forming Cyanobacteria

(2008) Nadine Ziemert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovering and improving novel peptide therapeutics

(2008) D MCGREGOR   CURRENT OPINION IN PHARMACOLOGY

Systematic Structure-Activity Analysis of Microcin J25

(2008) Olga Pavlova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation and Structural Characterization of Capistruin, a Lasso Peptide Predicted from the Genome Sequence of Burkholderia thailandensis E264

(2008) Thomas A. Knappe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A global assembly line for cyanobactins

(2008) Mohamed S Donia et al.   Nature Chemical Biology