Molecular mechanisms involved in podocyte EMT and concomitant diabetic kidney diseases: an update

Glycogen synthase kinase-3β is required for epithelial-mesenchymal transition and barrier dysfunction in mouse podocytes under high glucose conditions

(2016) Jia Guo et al.   Molecular Medicine Reports

FK506 reduces albuminuria through improving podocyte nephrin and podocin expression in diabetic rats

(2015) X.-M. Qi et al.   INFLAMMATION RESEARCH

Blocking Ligand Occupancy of the αVβ3 Integrin Inhibits the Development of Nephropathy in Diabetic Pigs

(2014) Laura A. Maile et al.   ENDOCRINOLOGY

High Glucose Induces Podocyte Injury via Enhanced (Pro)renin Receptor-Wnt-β-Catenin-Snail Signaling Pathway

(2014) Caixia Li et al.   PLoS One

Alcohol-induced severe acute pancreatitis followed by hemolytic uremic syndrome managed with continuous renal replacement therapy

(2014) Peng Fu et al.   BMC Nephrology

Podocyte Dedifferentiation: A Specialized Process for a Specialized Cell

(2014) Carl James May et al.   Frontiers in Endocrinology

Inhibition of Src Kinase Blocks High Glucose-Induced EGFR Transactivation and Collagen Synthesis in Mesangial Cells and Prevents Diabetic Nephropathy in Mice

(2013) K. Taniguchi et al.   DIABETES

c-Abl mediates angiotensin II-induced apoptosis in podocytes

(2013) Xinghua Chen et al.   JOURNAL OF MOLECULAR HISTOLOGY

Epithelial-mesenchymal transition - activating transcription factors - multifunctional regulators in cancer

(2013) Minal Garg   World Journal of Stem Cells

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Rac1/PAK1 signaling promotes epithelial-mesenchymal transition of podocytes in vitro via triggering β-catenin transcriptional activity under high glucose conditions

(2012) Zhimei Lv et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Podocyte Wnt/ß-catenin pathway is activated by integrin-linked kinase in clinical and experimental focal segmental glomerulosclerosis

(2012) Marcelo A. Naves et al.   JOURNAL OF NEPHROLOGY

Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF- B acetylation and transcription

(2012) D. F. Allison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of the Wnt signaling pathway in incretin hormone production and function

(2012) Yu-ting A. Chiang et al.   Frontiers in Physiology

Wnt/β-Catenin Pathway in Podocytes Integrates Cell Adhesion, Differentiation, and Survival

(2011) Hideki Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Canonical Wnt/β-catenin signaling mediates transforming growth factor-β1-driven podocyte injury and proteinuria

(2011) Dan Wang et al.   KIDNEY INTERNATIONAL

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The podocyte cytoskeleton—key to a functioning glomerulus in health and disease

(2011) Gavin I. Welsh et al.   Nature Reviews Nephrology

Epithelial-mesenchymal transition in breast cancer progression and metastasis

(2011) Yifan Wang et al.   Chinese Journal of Cancer

Activation of Notch signaling pathway in HIV-associated nephropathy

(2010) Madhulika Sharma et al.   AIDS

Wnt/β-catenin signaling: A novel target for therapeutic intervention of fibrotic kidney disease

(2010) Inah Hwang et al.   ARCHIVES OF PHARMACAL RESEARCH

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis

(2010) Sonali Sonnylal et al.   ARTHRITIS AND RHEUMATISM

Molecular make-up of the glomerular filtration barrier

(2010) Jaakko Patrakka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Emergence of the Phosphoinositide 3-Kinase-Akt- Mammalian Target of Rapamycin Axis in Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition

(2010) Samy Lamouille et al.   CELLS TISSUES ORGANS

The Role of Notch Signaling Pathway in Epithelial-Mesenchymal Transition (EMT) During Development and Tumor Aggressiveness

(2010) Zhiwei Wang et al.   CURRENT DRUG TARGETS

Modulation of Notch-1 Signaling Alleviates Vascular Endothelial Growth Factor–Mediated Diabetic Nephropathy

(2010) Chun-Liang Lin et al.   DIABETES

Getting a Notch Closer to Understanding Diabetic Kidney Disease: FIG. 1.

(2010) Seon-Ho Ahn et al.   DIABETES

Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function

(2010) Mariana Murea et al.   KIDNEY INTERNATIONAL

 -Catenin mediates adriamycin-induced albuminuria and podocyte injury in adult mouse kidneys

(2010) E. Heikkila et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Notch Activation Differentially Regulates Renal Progenitors Proliferation and Differentiation Toward the Podocyte Lineage in Glomerular Disorders

(2010) Laura Lasagni et al.   STEM CELLS

Epithelial-Mesenchymal Transition as a Potential Explanation for Podocyte Depletion in Diabetic Nephropathy

(2009) Yukinari Yamaguchi et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

c-Jun N-terminal kinase (JNK) signaling: Recent advances and challenges

(2009) Marie A. Bogoyevitch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

(2009) Yadi Wu et al.   CANCER CELL

Nuclear Factor- B-Mediated Transforming Growth Factor- -Induced Expression of Vimentin Is an Independent Predictor of Biochemical Recurrence after Radical Prostatectomy

(2009) Q. Zhang et al.   CLINICAL CANCER RESEARCH

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Pathophysiological aspects of Wnt-signaling in endocrine disease

(2009) Sven Schinner et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Wnt/ -Catenin Signaling Promotes Podocyte Dysfunction and Albuminuria

(2009) C. Dai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

JNK1/2 siRNA inhibits transforming-growth factor-β1-induced connective tissue growth factor expression and fibrotic function in THSFs

(2009) Yuan Chang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Epithelial-to-Mesenchymal Transition Is a Potential Pathway Leading to Podocyte Dysfunction and Proteinuria

(2008) Yingjian Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Wnt/β-catenin signaling: new (and old) players and new insights

(2008) He Huang et al.   CURRENT OPINION IN CELL BIOLOGY

Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF- 1

(2008) J. F. Alcorn et al.   JOURNAL OF CELL SCIENCE

Ectopic Notch Activation in Developing Podocytes Causes Glomerulosclerosis

(2008) A. M. Waters et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Notch pathway in podocytes plays a role in the development of glomerular disease

(2008) Thiruvur Niranjan et al.   NATURE MEDICINE

Alternative Wnt Signaling Is Initiated by Distinct Receptors

(2008) R. van Amerongen et al.   Science Signaling