ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis

 Np63  Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGF -Induced Metastasis

(2016) L. Rodriguez Calleja et al.   CANCER RESEARCH

Repression of p63 and induction of EMT by mutant Ras in mammary epithelial cells

(2016) Kathryn E. Yoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes

(2016) Bernard Pereira et al.   Nature Communications

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2

(2015) Hyun-Jung Choi et al.   Nature Communications

HER2/neuin Endometrial Cancer: A Promising Therapeutic Target With Diagnostic Challenges

(2014) Natalia Buza et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex

(2014) Wenjing Zhang et al.   CELL RESEARCH

Comprehensive molecular characterization of gastric adenocarcinoma

(2014) Adam J. Bass et al.   NATURE

ΔNp63α activates CD82 metastasis suppressor to inhibit cancer cell invasion

(2014) J Wu et al.   Cell Death & Disease

FOXO3 Promotes Quiescence in Adult Muscle Stem Cells during the Process of Self-Renewal

(2014) Suchitra D. Gopinath et al.   Stem Cell Reports

Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation

(2013) Guangwu Guo et al.   NATURE GENETICS

P63 regulates tubular formation via epithelial-to-mesenchymal transition

(2013) Y Zhang et al.   ONCOGENE

Rapamycin Inhibits IGF-1-Mediated Up-Regulation of MDM2 and Sensitizes Cancer Cells to Chemotherapy

(2013) Wei Du et al.   PLoS One

Integrative Genomic Characterization of Oral Squamous Cell Carcinoma Identifies Frequent Somatic Drivers

(2013) C. R. Pickering et al.   Cancer Discovery

p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome

(2012) Giustina Ferone et al.   HUMAN MOLECULAR GENETICS

The p63 Protein Isoform ΔNp63α Inhibits Epithelial-Mesenchymal Transition in Human Bladder Cancer Cells

(2012) Mai N. Tran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recurrent R-spondin fusions in colon cancer

(2012) Somasekar Seshagiri et al.   NATURE

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

(2012) J Bergholz et al.   ONCOGENE

Conditional activation of Pik3ca H1047R in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations

(2012) W Yuan et al.   ONCOGENE

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

(2012) P. Tucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors

(2012) Dalia Ercan et al.   Cancer Discovery

FOXO1 Inhibits Runx2 Transcriptional Activity and Prostate Cancer Cell Migration and Invasion

(2011) H. Zhang et al.   CANCER RESEARCH

Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway–dependent and PI3K pathway–independent mechanisms

(2011) Pixu Liu et al.   NATURE MEDICINE

Activation of ERBB2 Signaling Causes Resistance to the EGFR-Directed Therapeutic Antibody Cetuximab

(2011) K. Yonesaka et al.   Science Translational Medicine

Foxo3a Suppression of Urothelial Cancer Invasiveness through Twist1, Y-Box-Binding Protein 1, and E-Cadherin Regulation

(2010) M. Shiota et al.   CLINICAL CANCER RESEARCH

The role of HER2 in cancer therapy and targeted drug delivery

(2010) Wanyi Tai et al.   JOURNAL OF CONTROLLED RELEASE

Inactivation of Foxo3a and Subsequent Downregulation of PGC-1  Mediate Nitric Oxide-Induced Endothelial Cell Migration

(2010) S. Borniquel et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss of  Np63  Promotes Invasion of Urothelial Carcinomas via N-Cadherin/Src Homology and Collagen/Extracellular Signal-Regulated Kinase Pathway

(2009) H. Fukushima et al.   CANCER RESEARCH

ΔNp63α-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma

(2009) Koichiro Higashikawa et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Beyond Trastuzumab: Small Molecule Tyrosine Kinase Inhibitors in HER-2-Positive Breast Cancer

(2009) V. Roy et al.   ONCOLOGIST

FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

(2009) Y. Mei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

(2008) H. Yamamoto et al.   CANCER RESEARCH

p63 in epithelial development

(2008) E. Candi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders

(2008) Yoko Aoki et al.   HUMAN MUTATION

Trastuzumab treatment in patients with advanced or recurrent endometrial carcinoma overexpressing HER2/neu

(2008) Alessandro D. Santin et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

The FoxO code

(2008) D R Calnan et al.   ONCOGENE

FOXO3A genotype is strongly associated with human longevity

(2008) B. J. Willcox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA