The Ec-NhaA antiporter switches from antagonistic to synergistic antiport upon a single point mutation

Simulating the function of sodium/proton antiporters

(2015) Raphael Alhadeff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the sodium–proton antiporter NhaA dimer and new mechanistic insights

(2014) Chiara Lee et al.   JOURNAL OF GENERAL PHYSIOLOGY

NhaA Na+/H+ Antiporter Mutants That Hardly React to the Membrane Potential

(2014) Dudu Alkoby et al.   PLoS One

The Conserved nhaAR Operon Is Drastically Divergent between B2 and Non-B2 Escherichia coli and Is Involved in Extra-Intestinal Virulence

(2014) Mathilde Lescat et al.   PLoS One

Structure and substrate ion binding in the sodium/proton antiporter PaNhaP

(2014) David Wöhlert et al.   eLife

Common Folds and Transport Mechanisms of Secondary Active Transporters

(2013) Yigong Shi   Annual Review of Biophysics

Functional and structural dynamics of NhaA, a prototype for Na+ and H+ antiporters, which are responsible for Na+ and H+ homeostasis in cells

(2013) Etana Padan   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Na+/H+Antiport Is Essential for Yersinia pestis Virulence

(2013) Yusuke Minato et al.   INFECTION AND IMMUNITY

A two-domain elevator mechanism for sodium/proton antiport

(2013) Chiara Lee et al.   NATURE

Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in  -cells

(2013) C. Deisl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unconventional Chemiosmotic Coupling of NHA2, a Mammalian Na+/H+Antiporter, to a Plasma Membrane H+Gradient

(2012) Kalyan C. Kondapalli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Revealing the Ligand Binding Site of NhaA Na+/H+Antiporter and Its pH Dependence

(2012) Michal Maes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H+/Cl− exchanger

(2012) Alessandra Picollo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Site-Directed Alkylation Studies with LacY Provide Evidence for the Alternating Access Model of Transport

(2011) Xiaoxu Jiang et al.   BIOCHEMISTRY

Transport Mechanism and pH Regulation of the Na+/H+Antiporter NhaA fromEscherichia coli

(2011) Thomas Mager et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT

(2011) Nien-Jen Hu et al.   NATURE

Molecular aspects of bacterial pH sensing and homeostasis

(2011) Terry A. Krulwich et al.   NATURE REVIEWS MICROBIOLOGY

CLC channels and transporters: Proteins with borderline personalities

(2010) Alessio Accardi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Contribution of proton linkage to the thermodynamic stability of the major cold-shock protein of Escherichia coli CspA

(2010) Susan A. Petrosian et al.   PROTEIN SCIENCE

β-Sheet-dependent Dimerization Is Essential for the Stability of NhaA Na+/H+Antiporter

(2009) Katia Herz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NhaA crystal structure: functional-structural insights

(2009) E. Padan et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters

(2009) Alessandra Picollo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Combined computational and biochemical study reveals the importance of electrostatic interactions between the “pH sensor” and the cation binding site of the sodium/proton antiporter NhaA ofEscherichia coli

(2009) Elena Olkhova et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Molecular biology of the myocardial Na+/H+ exchanger

(2008) Larry Fliegel   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The enlightening encounter between structure and function in the NhaA Na+–H+ antiporter

(2008) Etana Padan   TRENDS IN BIOCHEMICAL SCIENCES