Structure of the Ebola virus envelope protein MPER/TM domain and its interaction with the fusion loop explains their fusion activity

The role of cholesterol in membrane fusion

(2016) Sung-Tae Yang et al.   CHEMISTRY AND PHYSICS OF LIPIDS

The Roles of Histidines and Charged Residues as Potential Triggers of a Conformational Change in the Fusion Loop of Ebola Virus Glycoprotein

(2016) Jinwoo Lee et al.   PLoS One

Structural basis for membrane anchoring of HIV-1 envelope spike

(2016) J. Dev et al.   SCIENCE

Fusion of Enveloped Viruses in Endosomes

(2016) Judith M. White et al.   TRAFFIC

Insights into the Conformation of the Membrane Proximal Regions Critical to the Trimerization of the HIV-1 gp41 Ectodomain Bound to Dodecyl Phosphocholine Micelles

(2016) John M. Louis et al.   PLoS One

Tryptophan-Dependent Membrane Interaction and Heteromerization with the Internal Fusion Peptide by the Membrane Proximal External Region of SARS-CoV Spike Protein

(2015) Ying Liao et al.   BIOCHEMISTRY

A Practical Implicit Membrane Potential for NMR Structure Calculations of Membrane Proteins

(2015) Ye Tian et al.   BIOPHYSICAL JOURNAL

The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region

(2015) Beatriz Apellániz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Backbone structure of Yersinia pestis Ail determined in micelles by NMR-restrained simulated annealing with implicit membrane solvation

(2015) Francesca M. Marassi et al.   JOURNAL OF BIOMOLECULAR NMR

Viral membrane fusion

(2015) Stephen C. Harrison   VIROLOGY

Ebolavirus Evolution: Past and Present

(2015) Marc-Antoine de La Vega et al.   PLoS Pathogens

Ebola Virus and Severe Acute Respiratory Syndrome Coronavirus Display Late Cell Entry Kinetics: Evidence that Transport to NPC1+Endolysosomes Is a Rate-Defining Step

(2015) Rebecca M. Mingo et al.   JOURNAL OF VIROLOGY

Ebolavirus Entry Requires a Compact Hydrophobic Fist at the Tip of the Fusion Loop

(2014) S. M. Gregory et al.   JOURNAL OF VIROLOGY

Dissociation of the trimeric gp41 ectodomain at the lipid–water interface suggests an active role in HIV-1 Env-mediated membrane fusion

(2014) Julien Roche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Capturing Glimpses of an Elusive HIV Gp41 Prehairpin Fusion Intermediate

(2014) Lukas K. Tamm et al.   STRUCTURE

Conformational Properties of Peptides Corresponding to the Ebolavirus GP2 Membrane-Proximal External Region in the Presence of Micelle-Forming Surfactants and Lipids

(2013) Lauren K. Regula et al.   BIOCHEMISTRY

Multiple Cationic Amphiphiles Induce a Niemann-Pick C Phenotype and Inhibit Ebola Virus Entry and Infection

(2013) Charles J. Shoemaker et al.   PLoS One

Prefusion structure of syntaxin-1A suggests pathway for folding into neuronal trans-SNARE complex fusion intermediate

(2013) B. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural investigation of influenza virus hemagglutinin membrane-anchoring peptide

(2013) K. S. Mineev et al.   PROTEIN ENGINEERING DESIGN & SELECTION

HIV: Cell Binding and Entry

(2013) C. B. Wilen et al.   Cold Spring Harbor Perspectives in Medicine

HIV-1 gp41 Transmembrane Domain Interacts with the Fusion Peptide: Implication in Lipid Mixing and Inhibition of Virus–Cell Fusion

(2012) Eliran Moshe Reuven et al.   BIOCHEMISTRY

Marburg Virus Glycoprotein GP2: pH-Dependent Stability of the Ectodomain α-Helical Bundle

(2012) Joseph S. Harrison et al.   BIOCHEMISTRY

The transmembrane domain of caveolin-1 exhibits a helix–break–helix structure

(2012) Jinwoo Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Fusion Activity of HIV gp41 Fusion Domain Is Related to Its Secondary Structure and Depth of Membrane Insertion in a Cholesterol-Dependent Fashion

(2012) Alex L. Lai et al.   JOURNAL OF MOLECULAR BIOLOGY

A new player in the puzzle of filovirus entry

(2012) Judith M. White et al.   NATURE REVIEWS MICROBIOLOGY

The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol

(2012) P. J. Barrett et al.   SCIENCE

Filovirus Entry: A Novelty in the Viral Fusion World

(2012) Catherine L. Hunt et al.   Viruses-Basel

Filovirus entry into cells – new insights

(2012) Emily Happy Miller et al.   Current Opinion in Virology

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

(2011) Marceline Côté et al.   NATURE

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Structure and function of the complete internal fusion loop from Ebolavirus glycoprotein 2

(2011) S. M. Gregory et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transmembrane orientation and possible role of the fusogenic peptide from parainfluenza virus 5 (PIV5) in promoting fusion

(2011) J. E. Donald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Designed protein mimics of the Ebola virus glycoprotein GP2 α-helical bundle: Stability and pH effects

(2011) Joseph S. Harrison et al.   PROTEIN SCIENCE

Shallow Boomerang-shaped Influenza Hemagglutinin G13A Mutant Structure Promotes Leaky Membrane Fusion

(2010) Alex L. Lai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Analysis of a Nitroxide Side Chain in an α-Helix with Density Functional Theory

(2010) Dora Toledo Warshaviak et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Ebola haemorrhagic fever

(2010) Heinz Feldmann et al.   LANCET

Rotamer libraries of spin labelled cysteines for protein studies

(2010) Yevhen Polyhach et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Cellular Entry of Ebola Virus Involves Uptake by a Macropinocytosis-Like Mechanism and Subsequent Trafficking through Early and Late Endosomes

(2010) Mohammad F. Saeed et al.   PLoS Pathogens

Ebolavirus Is Internalized into Host Cells via Macropinocytosis in a Viral Glycoprotein-Dependent Manner

(2010) Asuka Nanbo et al.   PLoS Pathogens

Membrane interaction and structure of the transmembrane domain of influenza hemagglutinin and its fusion peptide complex

(2008) Ding-Kwo Chang et al.   BMC BIOLOGY

Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme

(2008) Judith M. White et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cell Adhesion Promotes Ebola Virus Envelope Glycoprotein-Mediated Binding and Infection

(2008) D. Dube et al.   JOURNAL OF VIROLOGY

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY