Critical role of SIK3 in mediating high salt and IL-17 synergy leading to breast cancer cell proliferation

EPRS is a critical mTORC1–S6K1 effector that influences adiposity in mice

(2017) Abul Arif et al.   NATURE

Oleanolic Acid Inhibits High Salt-Induced Exaggeration of Warburg-like Metabolism in Breast Cancer Cells

(2016) Suneetha Amara et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Sodium channel γENaC mediates IL-17 synergized high salt induced inflammatory stress in breast cancer cells

(2016) Suneetha Amara et al.   CELLULAR IMMUNOLOGY

Quantitative Sodium MR Imaging at 7 T: Initial Results and Comparison with Diffusion-weighted Imaging in Patients with Breast Tumors

(2016) Olgica Zaric et al.   RADIOLOGY

Pleiotropic Effects of Myocardial MMP-9 Inhibition to Prevent Ventricular Arrhythmia

(2016) Ching-Hui Weng et al.   Scientific Reports

The diverse oncogenic and tumor suppressor roles of salt-inducible kinase (SIK) in cancer

(2015) Wen-Qi Du et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

High salt intake as a multifaceted cardiovascular disease: new support from cellular and molecular evidence

(2015) Marcelo Perim Baldo et al.   HEART FAILURE REVIEWS

Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes

(2015) Yumi Itoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunity, inflammation, and cancer: an eternal fight between good and evil

(2015) Shabnam Shalapour et al.   JOURNAL OF CLINICAL INVESTIGATION

SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype

(2015) Maria Stella Lombardi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: Potential role in liver fibrosis

(2015) Suneetha Amara et al.   MOLECULAR IMMUNOLOGY

Inflammation and cancer: advances and new agents

(2015) Shanthini M. Crusz et al.   Nature Reviews Clinical Oncology

A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation

(2015) Guang Yang et al.   Cell Reports

Violacein inhibits matrix metalloproteinase mediated CXCR4 expression: Potential anti-tumor effect in cancer invasion and metastasis

(2014) Derek Platt et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

mTORC2 dictates Warburg effect and drug resistance

(2014) Kenta Masui et al.   CELL CYCLE

The origin and function of tumor-associated macrophages

(2014) Yang Liu et al.   Cellular & Molecular Immunology

Safety and Preliminary Evidence of Biologic Efficacy of a Mammaglobin-A DNA Vaccine in Patients with Stable Metastatic Breast Cancer

(2014) V. Tiriveedhi et al.   CLINICAL CANCER RESEARCH

Activation of EGFR and ERBB2 by Helicobacter pylori Results in Survival of Gastric Epithelial Cells With DNA Damage

(2014) Rupesh Chaturvedi et al.   GASTROENTEROLOGY

Hepatitis C Virus-Induced Changes in MicroRNA 107 (miRNA-107) and miRNA-449a Modulate CCL2 by Targeting the Interleukin-6 Receptor Complex in Hepatitis

(2014) N. J. Sarma et al.   JOURNAL OF VIROLOGY

Protective role of bortezomib in steatotic liver ischemia/reperfusion injury through abrogation of MMP activation and YKL-40 expression

(2014) Venkataswarup Tiriveedhi et al.   TRANSPLANT IMMUNOLOGY

CXCL12-CXCR4 axis promotes the natural selection of breast cancer cell metastasis

(2014) Yanan Sun et al.   TUMOR BIOLOGY

Salt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death

(2014) H Chen et al.   Cell Death & Disease

Chronic Inflammation and Cytokines in the Tumor Microenvironment

(2014) Glauben Landskron et al.   Journal of Immunology Research

Th17 Cells in Cancer: The Ultimate Identity Crisis

(2014) Stefanie R. Bailey et al.   Frontiers in Immunology

Role of PI3K/Akt and mTOR complexes in Th17 cell differentiation

(2013) Shigenori Nagai et al.   Annals of the New York Academy of Sciences

The Tumor Suppressor Kinase LKB1 Activates the Downstream Kinases SIK2 and SIK3 to Stimulate Nuclear Export of Class IIa Histone Deacetylases

(2013) Donald R. Walkinshaw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-major histocompatibility complex–induced obliterative airway disease: Selective role for CD4 and CD8 T cells in inducing immune responses to self-antigens

(2013) Venkataswarup Tiriveedhi et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Pre-transplant antibodies to Kα1 tubulin and collagen-V in lung transplantation: Clinical correlations

(2013) Venkataswarup Tiriveedhi et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Salt-Inducible Kinases 1 and 3 Negatively Regulate Toll-Like Receptor 4-Mediated Signal

(2013) So Yong Kim et al.   MOLECULAR ENDOCRINOLOGY

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

T Regulatory Cells Play a Significant Role in Modulating MHC Class I Antibody-Induced Obliterative Airway Disease

(2012) V. Tiriveedhi et al.   AMERICAN JOURNAL OF TRANSPLANTATION

cAMP-elevation mediated by β-adrenergic stimulation inhibits salt-inducible kinase (SIK) 3 activity in adipocytes

(2012) Christine Berggreen et al.   CELLULAR SIGNALLING

The mTOR Signalling Pathway in Human Cancer

(2012) Helena Pópulo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

HIF-1α signaling by airway epithelial cell K-α1-tubulin: Role in fibrosis and chronic rejection of human lung allografts

(2011) Venkataswarup Tiriveedhi et al.   CELLULAR IMMUNOLOGY

A shift in the collagen V antigenic epitope leads to T helper phenotype switch and immune response to self-antigen leading to chronic lung allograft rejection

(2011) V. Tiriveedhi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer

(2011) S Charoenfuprasert et al.   ONCOGENE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY