LSL-KrasG12D; LSL-Trp53R172H/+; Ink4flox/+; Ptf1/p48-Cre mice are an applicable model for locally invasive and metastatic pancreatic cancer
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Title
LSL-KrasG12D; LSL-Trp53R172H/+; Ink4flox/+; Ptf1/p48-Cre mice are an applicable model for locally invasive and metastatic pancreatic cancer
Authors
Keywords
Mouse models, Metastatic tumors, Invasive tumors, Cell staining, Mice, Adenocarcinomas, Immunofluorescence staining, Lectins
Journal
PLoS One
Volume 12, Issue 5, Pages e0176844
Publisher
Public Library of Science (PLoS)
Online
2017-05-06
DOI
10.1371/journal.pone.0176844
References
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Note: Only part of the references are listed.- Genetics and biology of pancreatic ductal adenocarcinoma
- (2016) Haoqiang Ying et al. GENES & DEVELOPMENT
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- (2015) Claudia Fiorini et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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- (2015) Chang-Il Hwang et al. JOURNAL OF PATHOLOGY
- Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment
- (2015) E. M. Alexandrova et al. NATURE
- Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
- (2015) Xiaofeng Zheng et al. NATURE
- Whole genomes redefine the mutational landscape of pancreatic cancer
- (2015) Nicola Waddell et al. NATURE
- Primary and Liver Metastasis–Derived Cell Lines From KrasG12D; Trp53R172H; Pdx-1 Cre Animals Undergo Apoptosis in Response to Triptolide
- (2015) Veena Sangwan et al. PANCREAS
- Pancreatic Adenocarcinoma
- (2015) David P. Ryan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genetic Progression of Pancreatic Cancer
- (2014) Robert W. Cowan et al. CANCER JOURNAL
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- Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
- (2013) Cosimo Commisso et al. NATURE
- Novel Pancreatic Cancer Cell Lines Derived from Genetically Engineered Mouse Models of Spontaneous Pancreatic Adenocarcinoma: Applications in Diagnosis and Therapy
- (2013) María P. Torres et al. PLoS One
- Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma
- (2012) Janel L. Kopp et al. CANCER CELL
- Genetically Engineered Mouse Models of Pancreatic Cancer
- (2012) Christoph Benedikt Westphalen et al. CANCER JOURNAL
- The Pancreas Cancer Microenvironment
- (2012) C. Feig et al. CLINICAL CANCER RESEARCH
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- (2012) Michael A Jacobetz et al. GUT
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- Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
- (2009) K. P. Olive et al. SCIENCE
- TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
- (2009) M. Olivier et al. Cold Spring Harbor Perspectives in Biology
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