Nucleolus association of chromosomal domains is largely maintained in cellular senescence despite massive nuclear reorganisation

The 3D Genome as Moderator of Chromosomal Communication

(2016) Job Dekker et al.   CELL

The redundancy of the mammalian heterochromatic compartment

(2016) Joan C Ritland Politz et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Chromatin Domains: The Unit of Chromosome Organization

(2016) Jesse R. Dixon et al.   MOLECULAR CELL

More than 10% of yeast genes are related to genome stability and influence cellular senescence via rDNA maintenance

(2016) Kimiko Saka et al.   NUCLEIC ACIDS RESEARCH

Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells

(2015) Jop Kind et al.   CELL

The Role of Chromosome Domains in Shaping the Functional Genome

(2015) Tom Sexton et al.   CELL

Nucleolar repression facilitates initiation and maintenance of senescence

(2015) Leixiang Yang et al.   CELL CYCLE

Grabbing the genome by the NADs

(2015) Timothy D. Matheson et al.   CHROMOSOMA

Principles of chromatin organization in yeast: relevance of polymer models to describe nuclear organization and dynamics

(2015) Renjie Wang et al.   CURRENT OPINION IN CELL BIOLOGY

The 4D nucleome: Evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments

(2015) Thomas Cremer et al.   FEBS LETTERS

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Three-dimensional genome architecture: players and mechanisms

(2015) Ana Pombo et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epigenetic regulation of ageing: linking environmental inputs to genomic stability

(2015) Bérénice A. Benayoun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

(2015) W. Zhang et al.   SCIENCE

Active human nucleolar organizer regions are interspersed with inactive rDNA repeats in normal and tumor cells

(2015) Karina Zillner et al.   Epigenomics

The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation

(2015) Fan Yang et al.   GENOME BIOLOGY

A genomics approach identifies senescence-specific gene expression regulation

(2014) Daniel H. Lackner et al.   AGING CELL

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

Chromatin maintenance and dynamics in senescence: a spotlight on SAHF formation and the epigenome of senescent cells

(2014) Armelle Corpet et al.   CHROMOSOMA

Nucleolus and nuclear periphery: Velcro for heterochromatin

(2014) Jan Padeken et al.   CURRENT OPINION IN CELL BIOLOGY

Recollections of a scientific journey published in human genetics: from chromosome territories to interphase cytogenetics and comparative genome hybridization

(2014) Thomas Cremer et al.   HUMAN GENETICS

A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli

(2014) Corey L. Smith et al.   MOLECULAR BIOLOGY OF THE CELL

Topologically associating domains are stable units of replication-timing regulation

(2014) Benjamin D. Pope et al.   NATURE

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements

(2013) Marco De Cecco et al.   AGING CELL

The Spatial Organization of the Human Genome

(2013) Wendy A. Bickmore   Annual Review of Genomics and Human Genetics

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Single-Cell Dynamics of Genome-Nuclear Lamina Interactions

(2013) Jop Kind et al.   CELL

Genome Architecture: Domain Organization of Interphase Chromosomes

(2013) Wendy A. Bickmore et al.   CELL

Large-scale chromatin organization: the good, the surprising, and the still perplexing

(2013) Andrew S Belmont   CURRENT OPINION IN CELL BIOLOGY

The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres

(2013) Anna Postepska-Igielska et al.   EMBO REPORTS

Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence

(2013) M. Sadaie et al.   GENES & DEVELOPMENT

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

(2013) P. P. Shah et al.   GENES & DEVELOPMENT

The shared genomic architecture of human nucleolar organizer regions

(2013) I. Floutsakou et al.   GENOME RESEARCH

Higher-order unfolding of satellite heterochromatin is a consistent and early event in cell senescence

(2013) Eric C. Swanson et al.   JOURNAL OF CELL BIOLOGY

Senescent cells harbour features of the cancer epigenome

(2013) Hazel A. Cruickshanks et al.   NATURE CELL BIOLOGY

Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data

(2013) Job Dekker et al.   NATURE REVIEWS GENETICS

Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation

(2012) Tamir Chandra et al.   MOLECULAR CELL

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Nucleolar Association and Transcriptional Inhibition through 5S rDNA in Mammals

(2012) Andrew M. Fedoriw et al.   PLoS Genetics

Lessons from senescence: Chromatin maintenance in non-proliferating cells

(2011) Taranjit Singh Rai et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16ink4a

(2011) Martin Kosar et al.   CELL CYCLE

Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

(2011) Yoko Hayashi-Takanaka et al.   NUCLEIC ACIDS RESEARCH

Genome organization in and around the nucleolus

(2011) Attila Németh et al.   TRENDS IN GENETICS

The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats

(2010) Claudio Guetg et al.   EMBO JOURNAL

Remodeling of nuclear architecture by the thiodioxoxpiperazine metabolite chaetocin

(2010) Doris Illner et al.   EXPERIMENTAL CELL RESEARCH

Chromatin structure as a mediator of aging

(2010) Jason Feser et al.   FEBS LETTERS

High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli

(2010) Silvana van Koningsbruggen et al.   MOLECULAR BIOLOGY OF THE CELL

Genome Organization and Function: A View from Yeast and Arabidopsis

(2010) Julio Sáez-Vásquez et al.   Molecular Plant

Chromosome Territories

(2010) T. Cremer et al.   Cold Spring Harbor Perspectives in Biology

Initial Genomics of the Human Nucleolus

(2010) Attila Németh et al.   PLoS Genetics

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

A new role of the rDNA and nucleolus in the nucleus—rDNA instability maintains genome integrity

(2008) Takehiko Kobayashi   BIOESSAYS

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE