More than 10% of yeast genes are related to genome stability and influence cellular senescence via rDNA maintenance

Ccr4-Not Regulates RNA Polymerase I Transcription and Couples Nutrient Signaling to the Control of Ribosomal RNA Biogenesis

(2015) R. Nicholas Laribee et al.   PLoS Genetics

A lifespan-extending form of autophagy employs the vacuole-vacuole fusion machinery

(2014) Fusheng Tang et al.   Autophagy

Inactivation of Yeast Isw2 Chromatin Remodeling Enzyme Mimics Longevity Effect of Calorie Restriction via Induction of Genotoxic Stress Response

(2014) Weiwei Dang et al.   Cell Metabolism

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

(2014) Johanna Flach et al.   NATURE

Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import

(2014) Chong He et al.   PLoS Genetics

Cellular Senescence in Yeast Is Regulated by rDNA Noncoding Transcription

(2013) Kimiko Saka et al.   CURRENT BIOLOGY

Ribosomal DNA and cellular senescence: new evidence supporting the connection between rDNA and aging

(2013) Austen R. D. Ganley et al.   FEMS YEAST RESEARCH

High-Resolution Mapping of Spontaneous Mitotic Recombination Hotspots on the 1.1 Mb Arm of Yeast Chromosome IV

(2013) Jordan St. Charles et al.   PLoS Genetics

Rtt109 Prevents Hyper-Amplification of Ribosomal RNA Genes through Histone Modification in Budding Yeast

(2013) Satoru Ide et al.   PLoS Genetics

An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast

(2012) Adam L. Hughes et al.   NATURE

Sir2 deletion prevents lifespan extension in 32 long-lived mutants

(2011) Joe R. Delaney et al.   AGING CELL

Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeast

(2011) Takehiko Kobayashi   CELLULAR AND MOLECULAR LIFE SCIENCES

The multifunctional Ccr4–Not complex directly promotes transcription elongation

(2011) Jennifer A. Kruk et al.   GENES & DEVELOPMENT

Repeat expansion in the budding yeast ribosomal DNA can occur independently of the canonical homologous recombination machinery

(2011) Jonathan Houseley et al.   NUCLEIC ACIDS RESEARCH

Spt10 and Spt21 Are Required for Transcriptional Silencing in Saccharomyces cerevisiae

(2010) Jennifer S. Chang et al.   EUKARYOTIC CELL

Chromatin dynamics mediated by histone modifiers and histone chaperones in postreplicative recombination

(2010) Hirohito Endo et al.   GENES TO CELLS

Elevated Histone Expression Promotes Life Span Extension

(2010) Jason Feser et al.   MOLECULAR CELL

The Effect of Replication Initiation on Gene Amplification in the rDNA and Its Relationship to Aging

(2009) Austen R.D. Ganley et al.   MOLECULAR CELL

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

A new role of the rDNA and nucleolus in the nucleus—rDNA instability maintains genome integrity

(2008) Takehiko Kobayashi   BIOESSAYS

Mrc1 and DNA Polymerase ɛ Function Together in Linking DNA Replication and the S Phase Checkpoint

(2008) Huiqiang Lou et al.   MOLECULAR CELL

Shortest-Path Network Analysis Is a Useful Approach toward Identifying Genetic Determinants of Longevity

(2008) J. R. Managbanag et al.   PLoS One