Active human nucleolar organizer regions are interspersed with inactive rDNA repeats in normal and tumor cells

A Targeting Modality for Destruction of RNA Polymerase I that Possesses Anticancer Activity

(2014) Karita Peltonen et al.   CANCER CELL

Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division

(2014) A. Grob et al.   GENES & DEVELOPMENT

Conditional Inactivation of Upstream Binding Factor Reveals Its Epigenetic Functions and the Existence of a Somatic Nucleolar Precursor Body

(2014) Nourdine Hamdane et al.   PLoS Genetics

Beyond sequencing: optical mapping of DNA in the age of nanotechnology and nanoscopy

(2013) Michal Levy-Sakin et al.   CURRENT OPINION IN BIOTECHNOLOGY

Subnuclear partitioning of rRNA genes between the nucleolus and nucleoplasm reflects alternative epiallelic states

(2013) F. Pontvianne et al.   GENES & DEVELOPMENT

The shared genomic architecture of human nucleolar organizer regions

(2013) I. Floutsakou et al.   GENOME RESEARCH

Micro- and nanoscale devices for the investigation of epigenetics and chromatin dynamics

(2013) Carlos A. Aguilar et al.   Nature Nanotechnology

Single-molecule analysis of combinatorial epigenomic states in normal and tumor cells

(2013) P. J. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nucleolus: an emerging target for cancer therapy

(2013) Nadine Hein et al.   TRENDS IN MOLECULAR MEDICINE

Epigenetic control of RNA polymerase I transcription in mammalian cells

(2012) Ingrid Grummt et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53

(2012) Megan J. Bywater et al.   CANCER CELL

Real-time analysis and selection of methylated DNA by fluorescence-activated single molecule sorting in a nanofluidic channel

(2012) B. R. Cipriany et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-molecule, genome-scale analyses of DNA modifications: exposing the epigenome with next-generation technologies

(2012) Karina Zillner et al.   Epigenomics

Single DNA Molecule Patterning for High-Throughput Epigenetic Mapping

(2011) Aline Cerf et al.   ANALYTICAL CHEMISTRY

Genome organization in and around the nucleolus

(2011) Attila Németh et al.   TRENDS IN GENETICS

Repetitive Elements May Comprise Over Two-Thirds of the Human Genome

(2011) A. P. Jason de Koning et al.   PLoS Genetics

Single Molecule Epigenetic Analysis in a Nanofluidic Channel

(2010) Benjamin R. Cipriany et al.   ANALYTICAL CHEMISTRY

The RNA Polymerase I Transcription Machinery: An Emerging Target for the Treatment of Cancer

(2010) Denis Drygin et al.   Annual Review of Pharmacology and Toxicology

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

(2010) Denis Drygin et al.   CANCER RESEARCH

Identification of epigenetic DNA modifications with a protein nanopore

(2010) Emma V. B. Wallace et al.   CHEMICAL COMMUNICATIONS

Nucleolar dominance and ribosomal RNA gene silencing

(2010) Sarah Tucker et al.   CURRENT OPINION IN CELL BIOLOGY

Global analysis of DNA methylation and transcription of human repetitive sequences.

(2010) Béatrice Horard et al.   Epigenetics

Direct detection of DNA methylation during single-molecule, real-time sequencing

(2010) Benjamin A Flusberg et al.   NATURE METHODS

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

(2010) Julie A. Law et al.   NATURE REVIEWS GENETICS

Hypomethylation of repeated DNA sequences in cancer

(2010) Jason P Ross et al.   Epigenomics

Human rRNA Gene Clusters Are Recombinational Hotspots in Cancer

(2009) D. M. Stults et al.   CANCER RESEARCH

Growth control and ribosome biogenesis

(2009) Harri Lempiäinen et al.   CURRENT OPINION IN CELL BIOLOGY

Loss of Bloom syndrome protein destabilizes human gene cluster architecture

(2009) Michael W. Killen et al.   HUMAN MOLECULAR GENETICS

Loss of Human Ribosomal Gene CpG Methylation Enhances Cryptic RNA Polymerase II Transcription and Disrupts Ribosomal RNA Processing

(2009) Thérèse Gagnon-Kugler et al.   MOLECULAR CELL

The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology

(2008) Brian McStay et al.   Annual Review of Cell and Developmental Biology

Optical mapping discerns genome wide DNA methylation profiles

(2008) Gene E Ananiev et al.   BMC MOLECULAR BIOLOGY

Epigenetic regulation of TTF-I-mediated promoter–terminator interactions of rRNA genes

(2008) Attila Németh et al.   EMBO JOURNAL

UBF levels determine the number of active ribosomal RNA genes in mammals

(2008) Elaine Sanij et al.   JOURNAL OF CELL BIOLOGY