Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD

The Effect of Colonization with Potentially Pathogenic Microorganisms on Efferocytosis in Chronic Obstructive Pulmonary Disease

(2016) Sandra Hodge et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Is Alveolar Macrophage Phagocytic Dysfunction in Children With Protracted Bacterial Bronchitis a Forerunner to Bronchiectasis?

(2016) Sandra Hodge et al.   CHEST

A small volume technique to examine and compare alveolar macrophage phagocytosis of apoptotic cells and non typeable Haemophilus influenzae (NTHi)

(2016) Miranda Ween et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720

(2016) Hai B. Tran et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Targeting sphingosine-1-phosphate signaling in lung diseases

(2016) David L. Ebenezer et al.   PHARMACOLOGY & THERAPEUTICS

Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases

(2015) Michael S. Donoviel et al.   FASEB JOURNAL

Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD)

(2015) Jameel Barnawi et al.   PLoS One

Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells

(2014) E. Fuerst et al.   ALLERGY

Critical Role of Spns2, a Sphingosine-1-Phosphate Transporter, in Lung Cancer Cell Survival and Migration

(2014) Eric Bradley et al.   PLoS One

Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells

(2013) Anja Völzke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network

(2012) Masayuki Nagahashi et al.   FASEB JOURNAL

Sphingosine-1-phosphate inhibits interleukin-1β-induced inflammation in human articular chondrocytes

(2012) MYUNG-HEE MOON et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

(2012) Shigetomo Fukuhara et al.   JOURNAL OF CLINICAL INVESTIGATION

Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway

(2011) Yapeng Gu et al.   JOURNAL OF CELL BIOLOGY

Decreased efferocytosis and mannose binding lectin in the airway in bronchiolitis obliterans syndrome

(2011) Sandra Hodge et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Expression profile of the sphingosine kinase signalling system in the lung of patients with chronic obstructive pulmonary disease

(2011) Fabian Cordts et al.   LIFE SCIENCES

Cigarette Smoke-Induced Changes to Alveolar Macrophage Phenotype and Function Are Improved by Treatment with Procysteine

(2010) Sandra Hodge et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Sphingosine 1-Phosphate Transporter, SPNS2, Functions as a Transporter of the Phosphorylated Form of the Immunomodulating Agent FTY720

(2010) Yu Hisano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutral sphingomyelinase 2 is activated by cigarette smoke to augment ceramide-induced apoptosis in lung cell death

(2009) Michal Levy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Therapeutic Role for Mannose-Binding Lectin in Cigarette Smoke–Induced Lung Inflammation?

(2009) Sandra Hodge et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Azithromycin Improves Macrophage Phagocytic Function and Expression of Mannose Receptor in Chronic Obstructive Pulmonary Disease

(2008) Sandra Hodge et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sphingosine-1-Phosphate Induces an Antiinflammatory Phenotype in Macrophages

(2008) Jeniter E. Hughes et al.   CIRCULATION RESEARCH

The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors

(2008) A. Kawahara et al.   SCIENCE